Source link : https://www.newshealth.biz/health-news/one-dose-of-mva-bn-moderately-effective-against-mpox/ A single dose of modified vaccinia Ankara–Bavarian Nordic (MVA-BN) vaccine is moderately effective in preventing mpox infection, according to findings from an emulated target trial. Analyzing information from several databases that included some 9800 adult men in Ontario, Canada, researchers found that one dose of MVA-BN was almost 60% effective in […]
Category:Health
Source link : https://www.newshealth.biz/health-news/fda-faces-blowback-over-regulating-lab-developed-tests/ The US Food and Drug Administration (FDA) plans to scrutinize the safety and efficacy of lab-developed tests — those designed, manufactured, and used in a single laboratory — far more thoroughly in the future. Under a rule finalized in April, the FDA will treat facilities that develop and use lab tests […]
Source link : https://www.newshealth.biz/health-news/biomarkers-in-cord-blood-may-predict-ad-in-newborns/ TOPLINE: Newborns who go on to develop atopic dermatitis (AD) show higher transepidermal water loss (TEWL) and cord blood serum levels of CCL17/thymus- and activation-regulated chemokine (TARC) and interleukin (IL) 31. METHODOLOGY: Researchers conducted a prospective study to evaluate the predictive role of serologic biomarkers and cutaneous markers and the development […]
Source link : https://www.newshealth.biz/health-news/junior-doctors-given-job-title-change-bma-requested/ Dr Lily Huang Dr Lily Huang, who works in London, supports the name change Junior doctors working across the NHS will now be called resident doctors instead – in a change intended to better reflect their expertise. The doctors union, the British Medical Association (BMA), which called for the change, called […]
Source link : https://www.newshealth.biz/health-news/4-key-factors-affect-how-much-weight-you-lose-on-glp-1-drugs/ Share on PinterestFour key factors can greatly impact how much weight people lose while taking GLP-1 drugs like Ozempic, Wegovy, Victoza, and Saxenda. Daniel Llao Calvet/Getty Images Researchers have used real-world data to identify key factors for long-term weight loss for patients taking GLP-1 drugs like Ozempic and Wegovy. The study […]
Source link : https://www.newshealth.biz/health-news/lymphedema-risk-no-higher-with-3-week-rt-regimen-in-early-breast-cancer/ A shorter radiotherapy (RT) course proved its mettle in early-stage breast cancer in terms of lymphedema risk, without negatively impacting survival outcomes, according to a phase III trial from France. In the HypoG-01 study, a 3-week course of moderately hypofractionated locoregional RT was noninferior to 5 weeks of normofractionated RT for […]
Source link : https://www.newshealth.biz/health-news/cbt-improved-sex-life-for-peri-and-post-menopausal-women/ CHICAGO — Peri- and post-menopausal women who had cognitive behavioral therapy (CBT) for sexual concerns reported improvements in a range of symptoms after four sessions, according to a small trial. Results included a significant change in overall score on the Female Sexual Function Index (FSFI; Cohen’s d 0.87, P Author : […]
Source link : https://www.newshealth.biz/health-news/eye-drop-company-in-fdas-sights-once-again/ The FDA has sent another letter — this time a warning letter — to a company that it previously flagged for marketing amniotic fluid eye drops. In a letter to Carl Harrell, MD, CEO of Regenerative Processing Plant in Palm Harbor, Florida, the agency said the company’s Regener-Eyes Pro and Regener-Eyes […]
Source link : https://www.newshealth.biz/health-news/fda-expands-approval-of-ribociclib-to-early-breast-cancer/ The FDA on Tuesday approved ribociclib (Kisqali) in combination with endocrine therapy as adjuvant treatment for early high-risk breast cancer. Already approved in the metastatic setting, the CDK4/6 inhibitor is now also indicated for patients with stages II-III disease who have hormone receptor (HR)-positive/HER2-negative tumors and a high risk for recurrence […]
Source link : https://www.newshealth.biz/health-news/failing-wisely-can-promote-a-safer-healthcare-system/ Fleisher is a professor emeritus of Anesthesiology and Critical Care. Edmondson is a professor of Leadership and Management. The Institute of Medicine (IOM) published To Err is Human 24 years ago with a call for the healthcare community to focus on patient safety. Despite widespread attention to the report, improvements in […]
Source link : https://www.newshealth.biz/health-news/survival-win-for-pembrolizumab-in-early-triple-negative-breast-cancer/ PD-1 inhibition before and after surgery for high-risk early triple-negative breast cancer (TNBC) led to significant improvement in overall survival (OS), according to updated results from a large randomized trial. After a median follow-up of 75 months, the 5-year OS was 86.6% in patients who received pembrolizumab (Keytruda) before and after […]
Source link : https://www.newshealth.biz/health-news/cabozantinib-improves-pfs-for-advanced-neuroendocrine-tumors/ Cabozantinib (Cabometyx) significantly improved progression-free survival (PFS) in patients with previously treated, progressive advanced extrapancreatic or pancreatic neuroendocrine tumors (NETs), according to final results from the phase III CABINET trial. In the group of 203 patients with extrapancreatic NETs, the median PFS was 8.4 months with cabozantinib compared with 3.9 months […]
Source link : https://www.newshealth.biz/health-news/brain-training-and-memory-decline-alzheimers-pioneer-dies-notorious-apoe4/ In a 5-year follow-up study, cognitive training reduced memory decline in people with mild cognitive impairment. (Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring) Subcutaneous ocrelizumab and hyaluronidase (Ocrevus Zunovo) was approved for relapsing and progressive multiple sclerosis, Genentech said. The OCARINA II study supported the FDA’s decision. Erenumab (Aimovig) induced […]
Source link : https://www.newshealth.biz/health-news/here-are-the-best-private-healthcare-companies-to-work-for/ U.S. News & World Report has released its list of the best private companies to work for, including in healthcare. While the field of healthcare recently has been plagued by worker burnout and poor mental health, 23 healthcare entities made the list, ranging from those providing health insurance, to medical care […]
Source link : https://www.newshealth.biz/health-news/first-drug-okd-for-chronic-rhinosinusitis-with-nasal-polyps-in-adolescents/ The FDA broadened dupilumab’s (Dupixent) approval as an add-on maintenance treatment for chronic rhinosinusitis with nasal polyps to include adolescents as well, Regeneron Pharmaceuticals announced. With the expended indication, the interleukin (IL-4) receptor alpha antagonist is approved for use in children ages 12 to 17 years with inadequately controlled disease, making […]
Source link : https://www.newshealth.biz/health-news/coffee-caffeine-may-protect-cardiometabolic-health/ Share on PinterestModerate caffeine consumption may protect heart health and lower your risk of metabolic diseases. FG Trade/Getty Images New research suggests consuming three cups of coffee or 200–300 mg of caffeine daily may reduce the risk of developing cardiometabolic diseases compared to consuming little to none. Caffeine may improve cardiometabolic […]
Source link : https://www.newshealth.biz/health-news/fda-clears-first-1-year-continuous-glucose-sensor/ The US Food and Drug Administration (FDA) has cleared the Eversense 365 (Senseonics), an implanted continuous glucose monitoring (CGM) system that lasts a year. The Eversense is inserted subcutaneously into the upper arm by a certified healthcare professional during a brief office procedure. The transmitter is placed on the skin on […]
Source link : https://www.newshealth.biz/health-news/controversial-hungarian-gets-eu-health-portfolio-nomination/ European Commission (EC) President Ursula von der Leyen has appointed Olivér Várhelyi as commissioner for health and animal welfare for the next 5 years. Whether he takes the portfolio depends on the European Parliament. There, committees are due to hold extensive hearings before a parliamentary vote on the entire commission. Várhelyi […]
Source link : https://www.newshealth.biz/health-news/lpa-cutoffs-by-sex-lbba-pacing-approvals-loneliness-not-to-blame-for-cvd/ Study suggests men and women need distinct lipoprotein(a), or Lp(a), cutoffs to characterize their risk of heart disease. (Clinical Cardiology) Moderate coffee drinkers were at a relatively lower risk of developing co-existing cardiometabolic diseases. (Journal of Clinical Endocrinology & Metabolism) A group lifestyle intervention tailored for U.S. South Asian communities had […]
Source link : https://www.newshealth.biz/health-news/adjuvant-atezolizumab-plus-bevacizumab-strike-out-in-hcc/ The initial results of the IMbrave050 trial raised hopes that an effective adjuvant regimen for hepatocellular carcinoma (HCC) might finally have arrived. Patients with HCC treated with a combination of the immune checkpoint inhibitor atezolizumab and angiogenesis inhibitor bevacizumab after resection or ablation showed a 28% improvement in recurrence-free survival at […]
Source link : https://www.newshealth.biz/health-news/nurses-bore-the-brunt-of-covid-former-chief-nurse-says/ BBC Dame Ruth May was England’s chief nurse from 2019 until she retired in July 2024 Nurses bore the brunt of the pandemic, with low staffing levels and difficulties accessing protective equipment, according to England’s former chief nurse. Dame Ruth May told the Covid inquiry the NHS had been understaffed in […]
Source link : https://www.newshealth.biz/health-news/over-half-of-adults-with-uncontrolled-hypertension-unaware-of-their-condition/ More than half of U.S. adults with uncontrolled hypertension are unaware they have hypertension in the first place, according to a recent study in JAMA Network Open. Furthermore, more than two-thirds of those on treatment had hypertension that remained uncontrolled. In this video interview, study author Adam Vaughan, PhD, MPH, of […]
Source link : https://www.newshealth.biz/health-news/snoring-isnt-just-a-nuisance-its-dangerous-why-cant-we-treat-it/ Martin Parr/Magnum Photos It has ruined many a night’s sleep, and no doubt a lot of relationships too. Trying to sleep next to a snoring partner is exactly that: trying. Once the engines fire up, there are few countermeasures besides a shove, earplugs and the patience of a saint. That’s the […]
Source link : https://www.newshealth.biz/health-news/digital-breast-tomosynthesis-may-reduce-development-of-advanced-cancers/ Digital breast tomosynthesis (DBT) increased breast cancer detection rates and showed invasive cancers with a lower rate of advanced cancers compared with digital mammography, according to results from a retrospective study. In the review of 272,938 screenings for breast cancer, DBT had a higher cancer detection rate than digital mammography (5.3 […]
Source link : https://www.newshealth.biz/health-news/novel-plant-based-estrogen-cuts-menopause-symptoms/ CHICAGO — Daily treatment with a plant-based form of estrogen significantly eased vasomotor symptoms (VMS) in postmenopausal women, the primary efficacy analysis of a phase III trial showed. In the so-called E4Comfort II study, two different doses of oral estetrol (E4) reduced the frequency of moderate to severe VMS versus placebo […]
Source link : https://www.newshealth.biz/health-news/aad-reading-room-guidance-for-safe-use-of-deet-in-children/ A review in Pediatric Dermatology provides an overview of current evidence on the safe use of the popular insect repellent N, N-diethyl-3 meta-toluamide (DEET) in children. It outlines pediatric recommendations relating to DEET and federally approved and naturally-derived DEET alternatives that provide similar protection at a lower toxicity. First author, Helana […]
Source link : https://www.newshealth.biz/health-news/taking-on-inequities-in-pediatric-respiratory-care/ VIENNA — Health disparities have lasting effects on children’s respiratory health, but action at the community level can make a difference, according to experts in a session on diversity, equity, and inclusion in the pediatric asthma field at the European Respiratory Society (ERS) 2024 International Congress. Community-Level Challenges Health disparity is […]
Source link : https://www.newshealth.biz/health-news/untreated-brain-aneurysms-raise-mental-illness-risk/ Untreated unruptured intracranial aneurysms were linked to a 10% higher risk for mental illness, especially among younger people and those requiring psychotherapy. Medscape Medical News Source link : https://www.medscape.com/viewarticle/untreated-brain-aneurysms-raise-mental-illness-risk-2024a1000gva?src=rss Author : Publish date : 2024-09-17 14:40:36 Copyright for syndicated content belongs to the linked Source. Author : News Health Publish date […]
Source link : https://www.newshealth.biz/health-news/locally-acquired-dengue-case-confirmed-in-california/ A case of locally acquired dengue fever has been confirmed in a resident of Baldwin Park, California, according to a press release from the Los Angeles County Department of Public Health. This locally acquired case of dengue is the third to be reported in California and the first to be reported […]
Source link : https://www.newshealth.biz/health-news/why-many-women-opt-for-a-double-mastectomy/ Susan Derwin saw a call coming in. She had turned 60 that day, but this would not be a celebratory message. It was her doctor’s office calling, with results from her routine screening mammogram. Derwin was told the scan had picked up something in her left breast, and she would need […]
Source link : https://www.newshealth.biz/health-news/antipsychotics-tied-to-severe-respiratory-infection-risk/ TOPLINE: Antipsychotic use for schizophrenia or other psychotic disorders is associated with increased risk for severe COVID-19 or other respiratory infection and related hospitalization, a new retrospective study suggests. However, there was no link between antipsychotic use and mild infection outcomes. METHODOLOGY: Researchers analyzed data from several Danish registries on 85,083 […]
Source link : https://www.newshealth.biz/health-news/durvalumab-boosts-survival-in-muscle-invasive-bladder-cancer/ BARCELONA — Adding the immune checkpoint inhibitor durvalumab to standard treatment for muscle-invasive bladder cancer (MIBC) significantly improved survival, reducing the risk for death by 25%, according to a preplanned interim analysis of the phase 3 NIAGARA trial. These results offer practice-changing evidence in an area of unmet need, said lead […]
Source link : https://www.newshealth.biz/health-news/breastfeeding-safely-is-possible-following-breast-cancer/ BARCELONA, Spain — Breastfeeding is possible even after breast cancer, according to findings from two international studies led by Italian researchers, presented at the European Society for Medical Oncology (ESMO) Annual Meeting 2024. “Before this data, doctors tended to be cautious, if not outright defensive, about the possibility and safety of […]
Source link : https://www.newshealth.biz/health-news/daiichi-sankyo-mercks-cancer-drug-meets-main-goal-in-late-stage-trial/ (Reuters) -Daiichi Sankyo and Merck said on Tuesday that their drug, patritumab deruxtecan, met the main goal in a late-stage study in some patients with a type of lung cancer. The drug helped patients live significantly longer without their cancer progressing, compared with patients who were treated with chemotherapy, the companies […]
Source link : https://www.newshealth.biz/health-news/valley-fever-risk-uptick-with-drought-conditions/ The western United States is experiencing an uptick in Valley fever, an often asymptomatic disease, that may increase in response to climate change-related drought, according to some experts. As dry conditions continue, California residents and travelers to California’s Central Valley or Central Coast regions may need to remain vigilant for an […]
Source link : https://www.newshealth.biz/health-news/short-steroid-treatment-may-raise-diabetes-risk-study/ People who received systemic glucocorticoids during short hospital stays were more than twice as likely to develop new onset diabetes than those who didn’t, reported the authors of a large study that analyzed more than a decade’s worth of patient records. Rajna Golubic, MD, PhD, of the diabetes trials unit at […]
Source link : https://www.newshealth.biz/health-news/when-you-and-your-malpractice-insurer-disagree-on-your-case/ You’ve been sued for medical malpractice. If you are a physician in the United States, that is not an unlikely scenario. An analysis by the American Medical Association shows that almost half of all physicians are sued by the time they reach 54. In some specialties, such as OB/GYN, one is […]
Source link : https://www.newshealth.biz/health-news/pembrolizumab-plus-ccrt-improves-overall-survival/ BARCELONA, Spain — Adding pembrolizumab to standard concurrent chemoradiotherapy (CCRT) significantly improves overall survival in patients with high-risk, locally advanced cervical cancer, according to results of a phase 3, randomized, double-blind trial. Domenica Lorusso, MD, PhD, director of Gynecological Oncology at Humanitas San Pio X and professor at Humanitas University, Milan, […]
Source link : https://www.newshealth.biz/health-news/adenosine-safe-for-pediatric-tachyarrhythmia/ TOPLINE: Adenosine is safe for treating supraventricular tachycardia (SVT) in children in emergency settings, and patients have not experienced sustained ventricular tachycardia or prolonged cardiac pauses requiring intervention. METHODOLOGY: Researchers conducted a retrospective, cross-sectional, multi-hospital study involving 77 patients younger than 18 years (34 girls; median age, 9 years) treated with […]
Source link : https://www.newshealth.biz/health-news/hormone-therapy-for-menopause-remains-at-historic-lows/ CHICAGO — Less than 4% of American women aged 50-59 years use hormone therapy (HT) to treat menopausal symptoms today, approximately 10 times lower than the peak use of HT before the publication of the 2002 Women’s Health Initiative (WHI) study that misguidedly cast doubt on the safety of HT. Though […]
Categories
EHR Nudges and Primary Care Outcomes
Source link : https://www.newshealth.biz/health-news/ehr-nudges-and-primary-care-outcomes/ TOPLINE: Electronic health record (EHR) nudges were linked to improved documentation and patient-centeredness in primary care. However, their impact on other healthcare quality measures and patient outcomes was less consistent. METHODOLOGY: Researchers performed an electronic search on June 9, 2023, in PubMed, Embase, PsycINFO, CINAHL, and Web of Science for articles […]
Source link : https://www.newshealth.biz/health-news/clinicians-criticize-albertas-proposed-sex-ed-policy-change/ For decades, Canadian public health officials, researchers, and clinicians have worked hand in hand with government officials to stem the rise of preventable and treatable sexually transmitted infections (STIs) such as syphilis, gonorrhea, and chlamydia. But Alberta legislators are working to change the rules governing sexual health education even as the […]
Source link : https://www.newshealth.biz/health-news/most-women-with-gsm-lacked-adequate-treatment/ CHICAGO — The vast majority of women experiencing genitourinary syndrome of menopause (GSM) symptoms did not receive a prescription for hormonal vaginal therapies prior to seeking care at a specialized menopause clinic, according to research presented at the North American Menopause Society (NAMS) 2024 Annual Meeting in Chicago on September 12. […]
Source link : https://www.newshealth.biz/health-news/is-obesity-linked-to-pediatric-hidradenitis-suppurativa/ TOPLINE: Children with hidradenitis suppurativa (HS) are more likely to have obesity than those without the condition, a review suggests. METHODOLOGY: To evaluate the relationship between HS and obesity in children, an association that has been established in adults, researchers conducted a scoping review of 12 studies, which included one case […]
Source link : https://www.newshealth.biz/health-news/hypofractionated-rt-noninferior-for-locoregional-bc/ BARCELONA, Spain — Hypofractionated radiotherapy is noninferior to conventional fractionation for the locoregional treatment of early breast cancer, suggested new results of a phase 3 trial. Sofia Rivera, MD, PhD, presented these 5-year results of HypoG-01 at the European Society for Medical Oncology (ESMO) Annual Meeting 2024. Rivera, who is an […]
Source link : https://www.newshealth.biz/health-news/2024-pay-raise-not-enough-many-residents-feel-underpaid/ Medical resident salaries and stipends increased for 2024, but the majority of those surveyed say they still feel underpaid, according to Medscape Resident Salary & Debt Report 2024. Over the last 9 years, resident earnings have increased by just a combined 27%, considered slow growth given the rising cost of living. […]
Source link : https://www.newshealth.biz/health-news/radium-223-plus-enzalutamide-ups-survival-in-prostate-cancer/ BARCELONA, Spain — Adding bone-targeting radium-223 (Ra223) to the androgen receptor pathway inhibitor enzalutamide (Xtandi) in patients with metastatic castration-resistant prostate cancer and bone metastases significantly improves survival outcomes, according to the first results from the PEACE III trial. The research, presented at the European Society for Medical Oncology (ESMO) Annual […]
Source link : https://www.newshealth.biz/health-news/flavored-vape-use-cut-cigarette-smoking-in-high-risk-adults/ TOPLINE: E-cigarettes in preferred flavors (especially fruity and sweet) combined with very low nicotine content (VLNC) cigarettes reduce smoking behaviors in adults with psychiatric conditions or lower education levels, who are at the greatest risk for smoking-related harm. METHODOLOGY: Researchers hypothesized that cigarettes with VLNC used in combination with vapes that […]
Source link : https://www.newshealth.biz/health-news/antibiotic-resistance-forecast-to-kill-39-million-people-by-2050/ Some microbes have a growing resistance to our antibiotics iStockphoto The number of global deaths directly attributable to antibiotic-resistant bacterial infections is forecast to rise from a record 1.27 million a year in 2019 to 1.91 million a year by 2050. In total, antibiotic resistance is expected to kill 39 million […]
Source link : https://www.newshealth.biz/health-news/brain-changes-during-pregnancy-revealed-in-detailed-map/ Daniela Cossio Pregnancy brain really does exist, according to one of the first detailed maps of human-brain changes before, during and after those crucial nine months. Based on 26 scans of one healthy 38-year-old woman’s brain, scientists found “remarkable things” including changes to regions linked to socialising and emotional processing – […]
Source link : https://www.newshealth.biz/health-news/why-this-liquid-gold-supplement-from-cows-is-trending/ Share on PinterestBovine colostrum supplements, which are made from the first milk cows produce after giving birth, are skyrocketing in popularity thanks to claims they provide numerous health benefits. Lakeview Images/Getty Images Bovine colostrum supplements, also known as “liquid gold,” are growing in popularity, in part due to promotion from wellness […]
Source link : https://www.newshealth.biz/health-news/drug-resistant-bacteria-deaths-projected-to-rise-70-by-2050/ Antimicrobial-resistant bacterial infections directly caused more than 1 million deaths worldwide annually from 1990 to 2021, and that number is projected to increase by almost 70% over the next 25 years, according to a systematic analysis. In 2021, 1.14 million deaths that were attributable to bacterial antimicrobial resistance (AMR) occurred across […]
Source link : https://www.newshealth.biz/health-news/severe-sleep-issues-may-tell-of-later-suicidal-behavior-in-preteens/ Sleep disturbance may portend suicidal behavior among preteens, according to a longitudinal cohort study. A study of more than 8,000 kids found that those who reported severe sleep disturbances at age 10 had a higher odds of reporting suicidal ideation or attempt (OR 2.68, 95% CI 1.44-4.98, P=0.002) at age 12, […]
Source link : https://www.newshealth.biz/health-news/microplastics-found-in-human-olfactory-bulbs/ Microplastics were found in the olfactory bulbs of eight of 15 human brains at autopsy. A total of 16 different synthetic polymer particles and fibers were identified in olfactory bulbs. The olfactory pathway may be a potential entry route for microplastics into the brain. Microplastics were found in the olfactory bulbs […]
Source link : https://www.newshealth.biz/health-news/are-regulators-the-root-of-the-problem-of-serious-device-recalls/ Among cardiovascular devices that were deemed unsafe enough to warrant urgent regulatory action, many had been allowed to skip rigorous premarket clinical testing in the first place, a report showed. Researchers identified 137 Class I recalls affecting 157 unique cardiovascular devices logged by the FDA from 2013 to 2022. Of these […]
Source link : https://www.newshealth.biz/health-news/intimate-partner-violence-tied-to-working-memory-decline-into-menopause/ CHICAGO — Women who had experienced physical intimate partner violence experienced a decline in working memory as they transitioned into menopause, a subgroup analysis of the longitudinal Study of Women’s Health Across the Nation (SWAN) found. Reports of physical intimate partner violence in the year before SWAN baseline — when participants […]
Source link : https://www.newshealth.biz/health-news/type-2-diabetes-drug-metformin-may-also-help-people-with-hiv/ Share on PinterestMetformin, a common medication used to treat type 2 diabetes, may also help reduce the viral reservoir in people living with HIV who are undergoing antiretroviral therapy. Francis Dean/Corbis via Getty Images Research indicates that metformin could help reduce the viral reservoir in HIV patients. Metformin is currently used […]
Source link : https://www.newshealth.biz/health-news/medical-cannabinoids-in-kids-linked-to-these-adverse-events/ Cannabinoids used for medical purposes in children and adolescents come with a risk of adverse events, a systematic review and meta-analysis of 23 randomized clinical trials showed. The risk ratio (RR) of developing adverse events was higher in the cannabinoid group than in the control group (1.09, 95% CI 1.02-1.16), Lauren […]
Source link : https://www.newshealth.biz/health-news/win-for-perioperative-durvalumab-in-muscle-invasive-bladder-cancer/ Adding perioperative durvalumab (Imfinzi) to neoadjuvant chemotherapy significantly improved survival outcomes in cisplatin-eligible patients with muscle-invasive bladder cancer (MIBC), a phase III trial showed. Estimated 24-month event-free survival (EFS) rates reached 67.8% in the durvalumab group and 59.8% in the neoadjuvant chemotherapy-alone group (HR 0.68, 95% CI 0.56-0.82, P Author : […]
Source link : https://www.newshealth.biz/health-news/immediate-test-result-access-the-good-the-bad-and-the-complicated/ Fred Pelzman is an associate professor of medicine at Weill Cornell, and has been a practicing internist for nearly 30 years. He is medical director of Weill Cornell Internal Medicine Associates. “Dr. Pelzman, can you explain what all those scary little red arrows pointing up mean?” It feels like nearly every […]
Source link : https://www.newshealth.biz/health-news/another-possible-treatment-option-for-intermediate-stage-liver-cancer/ Progression-free survival (PFS) in intermediate-stage hepatocellular carcinoma (HCC) improved by almost 5 months when a targeted agent and immunotherapy were added to transarterial chemoembolization (TACE), initial results from a randomized trial showed. Median PFS increased from 10 months with TACE to 14.6 months with the addition of lenvatinib (Lenvima) and pembrolizumab […]
Source link : https://www.newshealth.biz/health-news/glp-1-drugs-in-masld-tied-to-lower-risk-of-cirrhosis-death/ GLP-1 receptor agonist use was associated with a reduced risk of progressing to cirrhosis and related complications in patients with diabetes and metabolic dysfunction-associated steatotic liver disease (MASLD), according to an analysis of Veterans Affairs data. In a matched cohort study of more than 30,000 patients, use of a GLP-1 agonist […]
Source link : https://www.newshealth.biz/health-news/high-intensity-noninvasive-ventilation-may-reduce-intubation-for-copd-exacerbation/ High-intensity noninvasive positive pressure ventilation (NPPV) might have reduced need for endotracheal intubation for persistent hypercapnia during acute exacerbation of chronic obstructive pulmonary disease (COPD), the randomized HAPPEN trial from China showed. NPPV adjusted to a tidal volume of 10-15 mL/kg of predicted body weight led to 4.8% of patients meeting […]
Source link : https://www.newshealth.biz/health-news/junior-doctors-accept-22-pay-rise-to-end-strikes/ Junior doctors in England have voted to accept the government’s offer of a 22% pay rise over two years, ending their long-running dispute. Members of the British Medical Association backed the deal with 66% voting in favour. It brings to an end the 18-month dispute, which saw junior doctors take part […]
Source link : https://www.newshealth.biz/health-news/brain-health-risks-digital-quality-measures-and-the-future-of-neurological-care/ Moura is a clinical neurologist and a health informatics expert. Ndemo is a clinical informatics manager. Weathers is a neurohospitalist and an associate chief medical information officer. As the American Academy of Neurology’s (AAN) Brain Health Summit convenes in September, it’s an opportune moment to explore the future of neurology and […]
Source link : https://www.newshealth.biz/health-news/scientists-show-how-pregnancy-changes-the-brain-in-innumerable-ways/ Neuroscientist Liz Chrastil, PhD, got the unique chance to see how her brain changed while she was pregnant and share what she learned in a new study that offers the first detailed map of a woman’s brain throughout gestation. The transition to motherhood, researchers discovered, affects nearly every part of the […]
Source link : https://www.newshealth.biz/health-news/the-complicated-role-loneliness-plays-in-26-common-health-conditions/ Loneliness is associated with multiple health conditions Marc Bruxelle RF / Alamy The idea that loneliness leads to certain health conditions is now being called into question. Although loneliness is associated with a range of negative physical health outcomes, including an increased risk of premature death, it might just be correlated […]
Source link : https://www.newshealth.biz/health-news/evidence-grows-for-dramatic-brain-remodelling-during-pregnancy/ Pregnancy may permanently change parts of the brain bernardbodo/iStockphoto/Getty Images The human brain goes through significant changes during pregnancy with few regions untouched, according to the first ever map of this over the course of gestation and beyond. Some regions of the brain shrink during this time, while others grow and […]
Source link : https://www.newshealth.biz/health-news/reproductive-rights-central-to-wisconsin-ob-gyns-run-for-congress/ As part of MedPage Today‘s occasional series on healthcare clinicians running for office, Washington Editor Joyce Frieden spoke with ob/gyn Kristin Lyerly, MD, a Democrat who is running for a U.S. House seat in Wisconsin. The winner of the election will fill both the unexpired term of Rep. Mike Gallagher (R), […]
Source link : https://www.newshealth.biz/health-news/what-factors-predict-clinically-meaningful-weight-loss-with-glp-1-agonists/ In this video interview, Hamlet Gasoyan, PhD, staff investigator at the Cleveland Clinic’s Center for Value-Based Care Research, discusses his recent study in JAMA Network Open that looked at the weight outcomes and factors associated with clinically meaningful weight loss at 1 year among patients with obesity receiving the GLP-1 agonists […]
Source link : https://www.newshealth.biz/health-news/chemo-free-triplet-yields-68-response-rate-in-richter-transformation/ A three-drug regimen involving a PD-L1 inhibitor and two targeted agents was active and safe for treating the diffuse large B-cell lymphoma (DLBCL) variant of Richter transformation, the phase II MOLTO study found. Among 28 previously untreated patients, the overall response rate reached 67.9% (95% CI 47.6-84.1) following six cycles of […]
Source link : https://www.newshealth.biz/health-news/uk-to-offer-vaccines-to-boost-mpox-protection/ Getty Images An mpox vaccine will be offered to thousands of men who have sex with men and some healthcare workers in the UK to boost protection against a form of the virus at the centre of an outbreak in parts of Africa, the government has said. It has bought more […]
Source link : https://www.newshealth.biz/health-news/conviction-for-fatal-covid-spread-who-is-alleged-trump-shooter-bmi-schizophrenia/ Note that some links may require registration or subscription. A woman in Austria was found guilty of grossly negligent homicide after fatally infecting her neighbor with COVID. (AP) COVID levels in the U.S. remain elevated, though some markers have declined, according to the CDC’s weekly update. Meanwhile, Florida is discouraging the […]
Source link : https://www.newshealth.biz/health-news/ai-tool-reduces-ehr-time-for-clinicians/ TOPLINE: An artificial intelligence (AI)-powered clinical documentation tool helped reduce time spent on electronic health records (EHR) at home for almost 48% physicians, and nearly 45% reported less weekly time spent on EHR tasks outside of normal work hours. METHODOLOGY: Researchers recruited 112 clinicians from family medicine, internal medicine, and general […]
Source link : https://www.newshealth.biz/health-news/new-xec-covid-variant-starting-to-spread/ Getty People have started catching a new Covid variant that could soon take off and become the dominant type, according to scientists. Identified in Germany, in June, cases of the XEC variant have since emerged in the UK, US, Denmark and several other countries, posters on X, formerly known as Twitter, […]
Source link : https://www.newshealth.biz/health-news/new-trials-in-breast-cancer-could-your-patient-benefit/ Several new clinical trials in breast cancer have opened in recent months. Perhaps one of your patients could benefit from taking part? Human epidermal growth factor receptor 2–positive (HER2+) or HER2-low unresectable or metastatic breast cancer. Adults with this type of breast cancer who have received one to three chemotherapies may […]
Source link : https://www.newshealth.biz/health-news/lpa1-receptor-affects-biomarkers-in-pulmonary-fibrosis/ VIENNA — Treatment with a novel lysophosphatidic acid receptor 1 (LPA1) antagonist was associated with significant changes in baseline biomarkers of disease in adults with pulmonary fibrosis, based on data from more than 300 individuals. “Lysophosphatidic acid receptor signaling is central to the pathogenesis of fibrotic lung diseases,” said Toby M. […]
Source link : https://www.newshealth.biz/health-news/perioperative-regional-anesthesia-less-pain-fewer-pills/ TOPLINE: The use of regional anesthesia reduces acute postoperative pain associated with noncardiac surgery. It also decreases the incidence of prolonged opioid use and chronic postoperative pain at 3 and 6 months after surgery. METHODOLOGY: Researchers conducted a systematic review and meta-analysis of 37 randomized controlled trials involving 4948 adults (age, […]
Source link : https://www.newshealth.biz/health-news/als-blood-test-promises-accurate-earlier-diagnosis/ Researchers have developed a blood test for amyotrophic lateral sclerosis (ALS) that could lead to more rapid and accurate diagnosis when used alongside standard clinical evaluations. Investigators said the test can distinguish ALS from other neurologic conditions with similar symptoms and has an overall accuracy of nearly 100%. “We have developed […]
Source link : https://www.newshealth.biz/health-news/no-matched-sibling-donor-experts-debate-next-best-option/ At a conference on hematologic oncology, two sickle cell experts faced off in a debate about whether gene therapy or alternative stem-cell transplant is the best option for patients who don’t have an available matched sibling donor. “If there is an indication for intervention, for a curative therapy, in the absence […]
Source link : https://www.newshealth.biz/health-news/socioeconomic-and-molecular-factors-in-crc-survival/ TOPLINE: Socioeconomic status contributes to 29% of racial disparities in colorectal cancer survival, with molecular factors accounting for 10%. Black patients have worse overall survival than White patients, whereas Asian and Hispanic patients have better outcomes. METHODOLOGY: Researchers conducted a single-center cohort study at a tertiary-level cancer center, including 47,178 patients […]
Source link : https://www.newshealth.biz/health-news/expert-highlights-two-novel-drugs-for-eczema/ HUNTINGTON BEACH, California — If the number of recent drug approvals for atopic dermatitis (AD) is overwhelming, the future is unlikely to be any less challenging: According to the National Eczema Association, the current pipeline for AD includes 39 injectable medications, 21 oral agents, and 49 topicals, some with novel targets, […]
Categories
Laser Therapies Don’t Benefit GSM
Source link : https://www.newshealth.biz/health-news/laser-therapies-dont-benefit-gsm/ CHICAGO — Use of CO2 lasers and similar “energy-based” treatments result in little to no benefit for genitourinary syndrome of menopause (GSM) symptoms, according to research presented at the North American Menopause Society (NAMS) 2024 Annual Meeting in Chicago on September 12. “There was a concern that menopausal women are being […]
Source link : https://www.newshealth.biz/health-news/renewed-hope-in-advanced-anal-cancer-with-ici-chemo-combo/ BARCELONA, Spain — Adding retifanlimab, an anti–programmed cell death 1 (PD-1) monoclonal antibody, to carboplatin plus paclitaxel in inoperable locally recurrent or metastatic squamous cell carcinoma (SCC) of the anal canal markedly improves survival outcomes, findings from the POD1UM-303 trial showed. The research, presented at the European Society for Medical Oncology […]
Source link : https://www.newshealth.biz/health-news/five-unique-clusters-identified-in-anca-vasculitis/ TOPLINE: A data-driven subclassification of antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis has identified five distinct clusters with varying degrees of kidney involvement and systemic inflammation, offering insights into improved patient stratification and treatment approaches. METHODOLOGY: ANCA-associated vasculitis is a rare and complex autoimmune disease that is traditionally classified into granulomatosis with polyangiitis […]
Source link : https://www.newshealth.biz/health-news/will-new-obesity-drugs-make-bariatric-surgery-obsolete/ MADRID — In spirited presentations at the European Association for the Study of Diabetes (EASD) 2024 Annual Meeting, Louis J. Aronne, MD, of Weill Cornell Medicine in New York City, made a compelling case that the next generation of obesity medications will make bariatric surgery obsolete, and Francesco Rubino, MD, of […]
Source link : https://www.newshealth.biz/health-news/fda-oks-subcutaneous-atezolizumab-for-multiple-cancers/ The US Food and Drug Administration (FDA) has approved atezolizumab and hyaluronidase-tqjs (Tecentriq Hybreza, Genentech, Inc.) as a subcutaneous injection in adults, covering all approved indications of the intravenous (IV) formulation. Approved indications include non–small-cell lung cancer (NSCLC), small-cell lung cancer, hepatocellular carcinoma, melanoma, and alveolar soft part sarcoma. Specific indications […]
Source link : https://www.newshealth.biz/health-news/missed-opportunities-for-early-lung-cancer-detection/ SAN DIEGO — New research highlights a mismatch between lung cancer screening eligibility criteria and actual lung cancer risk, which means many patients who develop lung cancer are not captured by the current criteria and don’t receive early screening. The analysis revealed that only 6% patients with lung cancer were screened […]
Source link : https://www.newshealth.biz/health-news/fewer-adolescents-are-using-condoms-says-who-report/ The use of condoms among sexually active adolescents in European countries has significantly decreased since 2014. A recent World Health Organization (WHO) report showed that the percentage of adolescents who used a condom during their last sexual intercourse decreased from 70% to 61% for boys and from 63% to 57% for […]
Source link : https://www.newshealth.biz/health-news/burnout-is-a-significant-problem-among-european-oncologists/ Burnout, a syndrome caused by work overload, is one of the main challenges in the medical profession. Although it is a general problem, certain professionals, such as oncologists, are more affected by this issue. Oncologists face two burdens: The high patient load in a context of healthcare cuts and the emotional […]
Source link : https://www.newshealth.biz/health-news/does-tailored-acupuncture-relieve-chronic-neck-pain/ TOPLINE: Patients with chronic neck pain who received acupuncture experienced an alleviation of their symptoms, but not at clinically meaningful levels, compared with those who received sham treatment. METHODOLOGY: A 24-week randomized trial was conducted at four clinical centers in China over a 2-year period starting in 2018. A total of […]
Source link : https://www.newshealth.biz/health-news/long-term-data-support-non-hormonal-drug-for-hot-flash-management/ CHICAGO — The non-hormonal drug elinzanetant reduced the frequency of moderate-to-severe hot flashes in postmenopausal women, and seemed to have a favorable safety profile, according to long-term OASIS 3 trial data. Women with moderate-to-severe vasomotor symptoms (VMS) treated with elinzanetant for 12 weeks had an average of 1.6 hot flashes per […]
Source link : https://www.newshealth.biz/health-news/radionuclide-containing-combo-slows-metastatic-prostate-cancer-improves-survival/ Men with castration-resistant prostate cancer (CRPC) and asymptomatic or mildly symptomatic bone metastases lived significantly longer when they received enzalutamide (Xtandi) plus radium-223 (Ra-223, Xofigo), a large randomized trial showed. Median radiographic progression-free survival (rPFS), the primary endpoint, improved from 16.4 months with enzalutamide along with 19.4 months with the addition […]
Source link : https://www.newshealth.biz/health-news/worse-pfs-seen-with-nivolumab-rucaparib-in-ovarian-cancer/ The addition of nivolumab to rucaparib did not lead to better progression-free survival than rucaparib monotherapy in patients with newly diagnosed, advanced, high-grade ovarian cancer (AHGOC), a new study has found. Bradley J. Monk, MD, presented this finding and other results of the ATHENA-COMBO study, at the European Society for Medical […]
Source link : https://www.newshealth.biz/health-news/is-it-safe-to-hit-a-kid-in-the-head-200-times-what-we-heard-this-week/ “Is it safe to hit a kid in the head 200 times?” — Chris Nowinski, PhD, of the Concussion Legacy Foundation in Boston, on head trauma in youth football. “These laws are just incompatible with evidence-based medical care, and the bans need to be repealed.” — Daniel Grossman, MD, of Advancing […]
Source link : https://www.newshealth.biz/health-news/t-dxd-effective-in-some-with-her2-breast-cancer/ A study demonstrated the efficacy of trastuzumab deruxtecan (Enhertu) in patients with HER2-positive advanced or metastatic breast cancer, including those with brain metastases. Senior author Nancy Lin, MD, presented these primary results of the DESTINY-Breast12 trial at the European Society for Medical Oncology Congress 2024. These findings were published simultaneously in […]
Source link : https://www.newshealth.biz/health-news/haunting-questions-about-a-lethal-american-virus/ Claire Panosian Dunavan is a professor of medicine and infectious diseases at the David Geffen School of Medicine at UCLA and a past-president of the American Society of Tropical Medicine and Hygiene. Glowing embers cascading from Glacier Point. The ancient granite of Tuolumne Meadows. The Mist Trail leading to Vernal Falls. […]
Source link : https://www.newshealth.biz/health-news/retifanlimab-chemo-combo-boosts-pfs-in-advanced-squamous-cell-anal-cancer/ Combining retifanlimab (Zynyz) with standard-of-care chemotherapy significantly improved progression-free survival (PFS) in treatment-naïve patients with locally advanced or metastatic squamous cell carcinoma of the anal canal (SCAC), according to phase III trial results. PFS was 9.3 months for patients treated with the anti-PD-1 monoclonal antibody versus 7.4 months for those treated […]
Source link : https://www.newshealth.biz/health-news/a-new-option-to-treat-intermediate-hepatocellular-carcinoma/ BARCELONA — Adding lenvatinib and pembrolizumab to transarterial chemoembolization (TACE) led to a significant improvement in progression-free survival in patients with intermediate-stage hepatocellular carcinoma compared with TACE plus placebo, according to findings from the first interim analysis of the phase 3 LEAP-012 study. The results, presented here at the European Society […]
Source link : https://www.newshealth.biz/health-news/how-many-of-us-will-end-up-being-diagnosed/ BBC The number of people taking ADHD medication is at a record high – and the NHS is feeling the strain as it tries to diagnose and treat the condition. Since 2015, the number of patients in England prescribed drugs to treat ADHD has nearly trebled, and BBC research suggests that […]