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Novel Monoclonal Antibody Protects Infants Against RSV

Source link : https://www.newshealth.biz/health-news/novel-monoclonal-antibody-protects-infants-against-rsv/ The investigational monoclonal antibody clesrovimab protected against respiratory syncytial virus (RSV) disease and prevented RSV hospitalizations among healthy preterm- and term infants, according to results of a phase IIb/III study. A single dose of clesrovimab reduced the incidence of RSV-associated medically attended lower respiratory infections (MALRI) that had at least one […]

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Rainfall and Mortality; Identifying Risk for Preeclampsia

Source link : https://www.newshealth.biz/health-news/rainfall-and-mortality-identifying-risk-for-preeclampsia/ TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center in El Paso, look at the top medical stories of the week. This week’s topics include […]

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Informed Consent, Inclusion Prioritized in Revised Ethics for Human Trials

Source link : https://www.newshealth.biz/health-news/informed-consent-inclusion-prioritized-in-revised-ethics-for-human-trials/ The World Medical Association (WMA) voted unanimously today to approve revised ethical principles for human participants in medical research. Updates to the WMA “Declaration of Helsinki” (DoH) include: Respecting “individual autonomy” through “[f]ree and informed consent” that is given voluntarily by the person who will participate in the research Replacing the […]

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Women and Children First — Or Not

Source link : https://www.newshealth.biz/health-news/women-and-children-first-or-not/ Rosenbaum is a pediatrician, and a professor emeritus and special lecturer in pediatrics and medicine. Meyer is a professor of pediatrics and medical director for the community and population health division of a large hospital system. We are both pediatricians and parents. We have patients and children of our own, and […]

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Whooping Cough in the U.S. Is at a Decade-High Level

Source link : https://www.newshealth.biz/health-news/whooping-cough-in-the-u-s-is-at-a-decade-high-level/ Whooping cough is at its highest level in a decade for this time of year, U.S. health officials reported Thursday. There have been 18,506 cases of whooping cough reported so far, the CDC said. That’s the most at this point in the year since 2014, when cases topped 21,800. The increase […]

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How will weight-loss drugs change our relationship with food?

Source link : https://www.newshealth.biz/health-news/how-will-weight-loss-drugs-change-our-relationship-with-food/ BBC We are now in the era of weight-loss drugs. Decisions on how these drugs will be used look likely to shape our future health and even what our society might look like. And, as researchers are finding, they are already toppling the belief that obesity is simply a moral failing […]

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Drugmaker Pulls Trodelvy’s Bladder Cancer Approval

Source link : https://www.newshealth.biz/health-news/drugmaker-pulls-trodelvys-bladder-cancer-approval/ Sacituzumab govitecan’s (Trodelvy) accelerated approval in urothelial cancer will be voluntarily withdrawn, Gilead Sciences announced on Friday. The decision was made in consultation with the FDA and does not affect the antibody-drug conjugate’s other indications, the company said. A Trop-2-directed antibody, sacituzumab govitecan was granted accelerated approval for urothelial cancer in […]

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Immunotherapy and Immune-Related Adverse Events

Source link : https://www.newshealth.biz/health-news/immunotherapy-and-immune-related-adverse-events/ While immunotherapy has revolutionized the way in which oncologists treat cancer, its use comes with a variety of side effects that are very different from those seen with other systemic therapies. These treatments are “revving up the immune system,” said Bryan J. Schneider, MD, of the University of Michigan in Ann […]

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Study: OUD Patients More Likely to Stay on Methadone Than Buprenorphine/Naloxone

Source link : https://www.newshealth.biz/health-news/study-oud-patients-more-likely-to-stay-on-methadone-than-buprenorphine-naloxone/ Patients with opioid use disorder (OUD) had a lower risk of discontinuing methadone compared with buprenorphine/naloxone, and with a similar mortality risk, according to a population-based cohort study published in JAMA. In this video interview, researcher Bohdan Nosyk, PhD, of Simon Fraser University in Burnaby, British Columbia, discusses the findings and […]

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Teen Smoking, Other Tobacco Use Dropped to Lowest Level in 25 Years, CDC Reports

Source link : https://www.newshealth.biz/health-news/teen-smoking-other-tobacco-use-dropped-to-lowest-level-in-25-years-cdc-reports/ Teen smoking hit an all-time low in the U.S. this year, part of a big drop in the use of tobacco among youths overall, the CDC reported Thursday. There was a 20% drop in the estimated number of middle and high school students who recently used at least one tobacco product, […]

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‘Virtual ED’ Helps One Health System Avoid Unnecessary Emergency Department Visits

Source link : https://www.newshealth.biz/health-news/virtual-ed-helps-one-health-system-avoid-unnecessary-emergency-department-visits/ WASHINGTON — Use of a “virtual” emergency department (ED) has saved several patients from unnecessary ED trips in its first few weeks of operation, Sidney “Beau” Raymond, MD, said here Thursday at the fall conference of the National Association of ACOs (NAACOS). “When you talk about impact on people who are […]

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Diet and Prostate Cancer; TTFields OK’d for NSCLC; Cancer Studies Retracted

Source link : https://www.newshealth.biz/health-news/diet-and-prostate-cancer-ttfields-okd-for-nsclc-cancer-studies-retracted/ A healthy diet in prostate cancer patients on active surveillance was associated with a reduced risk of progressing to a more advanced disease state. (JAMA Oncology) Some doctors see a potential downside to FDA’s new requirement to notify women about breast density. (NBC News) Jazz Pharmaceuticals announced that adding lurbinectedin (Zepzelca) […]

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Novel Targeted Drug Approved for Stomach Cancers

Source link : https://www.newshealth.biz/health-news/novel-targeted-drug-approved-for-stomach-cancers/ The FDA approved zolbetuximab (Vyloy), a claudin 18.2 (CLDN18.2)-directed cytolytic antibody, in combination with chemotherapy for the first-line treatment of adults with advanced HER2-negative gastric or gastroesophageal junction (GEJ) adenocarcinoma, the agency announced Friday. “While there have been advances in the first-line treatment of locally advanced unresectable and metastatic gastric and […]

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FDA OKs Zolbetuximab for Gastric, Gastroesophageal Cancer

Source link : https://www.newshealth.biz/health-news/fda-oks-zolbetuximab-for-gastric-gastroesophageal-cancer/ The US Food and Drug Administration (FDA) has approved zolbetuximab (Vyloy, Astellas Pharma) in combination with fluoropyrimidine and platinum-containing chemotherapy for the first-line treatment of locally advanced unresectable or metastatic HER2-negative gastric or gastroesophageal junction adenocarcinoma that is claudin 18.2 positive.  FDA also approved the Ventana CLDN18 (43-14A) RxDx Assay, from […]

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Tpoxx No Better Than Placebo for Clade I Mpox

Source link : https://www.newshealth.biz/health-news/tpoxx-no-better-than-placebo-for-clade-i-mpox/ The antiviral drug tecovirimat (Tpoxx) failed to shorten the duration of mpox lesions or lower mortality among children and adults with clade I mpox in the Democratic Republic of the Congo (DRC), according to results from the randomized, placebo-controlled PALM007 trial. Among hospitalized patients with mpox, lesion resolution took a median […]

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FDA OKs Novel Levodopa-Based Regimen for Parkinson’s

Source link : https://www.newshealth.biz/health-news/fda-oks-novel-levodopa-based-regimen-for-parkinsons/ The US Food and Drug Administration (FDA) has approved foscarbidopa and foslevodopa (Vyalev, AbbVie), a solution of carbidopa and levodopa prodrugs for 24-hour continuous subcutaneous infusion, for the treatment of motor fluctuations in adults with advanced Parkinson’s disease (PD).  Due to the progressive nature of PD, “oral medications are eventually no […]

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How Does This Year’s Flu Shot Stack Up?

Source link : https://www.newshealth.biz/health-news/how-does-this-years-flu-shot-stack-up/ Data from the southern hemisphere show that this year’s flu shot was 34.5% effective against hospitalization in high-risk groups during that half of the globe’s winter respiratory season. It’s not possible to say exactly how that will translate to the northern hemisphere’s upcoming flu season, but the figure is in the […]

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Doctors, Not AI, Should Authorize Treatments

Source link : https://www.newshealth.biz/health-news/doctors-not-ai-should-authorize-treatments/ Kanaparthy is a practicing internal medicine physician specializing in clinical informatics. Last month, California passed a bill ensuring that doctors, not artificial intelligence (AI), have the final say on patients’ treatments and services. The bill, SB1120, allows insurance companies to use AI to review doctors’ recommendations for medical procedures only if […]

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New Flu and Updated COVID Vaccines Greenlighted by Europe

Source link : https://www.newshealth.biz/health-news/new-flu-and-updated-covid-vaccines-greenlighted-by-europe/ Europe’s Committee for Medicinal Products for Human Use (CHMP) recommended granting marketing authorization for two vaccines: Fluad (surface antigen, inactivated, adjuvanted) and Flucelvax (surface antigen, inactivated, prepared in cell cultures) for active immunization against influenza. Together, the vaccines can immunize children from 2 years and older, adults, and those with comorbidities […]

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Generic Medicine OKd by Europe for Thrombocytopenia With HCV

Source link : https://www.newshealth.biz/health-news/generic-medicine-okd-by-europe-for-thrombocytopenia-with-hcv/ Europe’s Committee for Medicinal Products for Human Use (CHMP) has recommended granting a marketing authorization for Eltrombopag Viatris (eltrombopag), a generic medicine for the treatment of children and adults with primary immune thrombocytopenia (ITP), thrombocytopenia associated with chronic hepatitis C virus (HCV) infection, and acquired severe aplastic anemia. The application by […]

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EMA Confirms Rejection of Neurodegenerative Disease Drugs

Source link : https://www.newshealth.biz/health-news/ema-confirms-rejection-of-neurodegenerative-disease-drugs/ The European Medicines Agency (EMA) has upheld an earlier recommendation to deny marketing authorization for Masitinib AB Science (masitinib), an oral treatment for amyotrophic lateral sclerosis (ALS).  In a meeting on October 17, the EMA’s Committee for Medicinal Products for Human Use (CHMP) reaffirmed its concerns about the reliability of the […]

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Gene Therapy Details Revealed in Duchenne Trial

Source link : https://www.newshealth.biz/health-news/gene-therapy-details-revealed-in-duchenne-trial/ SAVANNAH, Ga. — Delandistrogene moxeparvovec (Elevidys), a gene therapy approved to treat Duchenne muscular dystrophy, missed its primary endpoint but differences emerged in other functional outcomes, the phase III EMBARK trial showed. The primary outcome was the change from baseline in North Star Ambulatory Assessment (NSAA) scores at 1 year. The […]

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EMA OKs Sublingual Formulation for Opioid Dependence

Source link : https://www.newshealth.biz/health-news/ema-oks-sublingual-formulation-for-opioid-dependence/ The European Medicines Agency has recommended granting marketing authorization for a new hybrid formulation of buprenorphine as a substitution treatment of opioid drug dependence. Buprenorphine Neuraxpharm is available as multiple-strength sublingual films. The Committee for Medicinal Products for Human Use (CHMP) said its recommendation was intended to cover use in adults […]

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EMA Recommends New Diagnostic Tool for TB

Source link : https://www.newshealth.biz/health-news/ema-recommends-new-diagnostic-tool-for-tb/ A new diagnostic tool for detecting Mycobacterium tuberculosis infection should be granted a marketing authorization, the European Medicines Agency (EMA) has said. On October 17, the EMA’s Committee for Medicinal Products for Human Use concluded that the Siiltibcy skin test showed favorable results compared with two other diagnostic products. Manufactured by the […]

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EMA Authorizes Korjuny for Malignant Ascites

Source link : https://www.newshealth.biz/health-news/ema-authorizes-korjuny-for-malignant-ascites/ In its October 2024 meeting, the European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP) gave the green light for Korjuny (catumaxomab, Lindis Biotech GmbH) to be used for the intraperitoneal treatment of malignant ascites in patients not eligible for further systemic anticancer therapy. The active substance of […]

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Ruxolitinib Cream Shows Promise in Treating Lichen Planus

Source link : https://www.newshealth.biz/health-news/ruxolitinib-cream-shows-promise-in-treating-lichen-planus/ AMSTERDAM — Treatment with ruxolitinib cream, 1.5%, achieved rapid and marked reductions in the clinical signs and symptoms of cutaneous lichen planus, including itch and skin pain, both when given twice daily and as needed, according to data from a phase 2 trial. The research, presented at the European Academy of […]

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EHR Prompt Cut Acute Otitis Media Antibiotic Use by Half

Source link : https://www.newshealth.biz/health-news/ehr-prompt-cut-acute-otitis-media-antibiotic-use-by-half/ LOS ANGELES — Embedding a new discharge order set into electronic health records (EHRs) with a preselected 5-day antibiotic course for children aged 2 years or older diagnosed with acute otitis media (AOM) cut antibiotic duration sharply, according to new data presented at the Infectious Disease Week (IDWeek) 2024 Annual Meeting. […]

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Vestibular Migraine: Less Dizziness With Galcanezumab

Source link : https://www.newshealth.biz/health-news/vestibular-migraine-less-dizziness-with-galcanezumab/ TOPLINE: Galcanezumab was associated with significantly less dizziness in patients with vestibular migraine (VM) compared with placebo, suggests new results from the first randomized clinical trial in VM. METHODOLOGY: The INVESTMENT study was a single-site, double-blind, placebo-controlled randomized clinical trial with 40 participants (mean age, 51 years; 75% women) with a […]

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ACOG Updates Breast Cancer Screening Guidelines

Source link : https://www.newshealth.biz/health-news/acog-updates-breast-cancer-screening-guidelines/ The American College of Obstetricians and Gynecologists (ACOG) has updated its breast cancer screening guidelines, recommending that individuals at an average risk for breast cancer initiate mammography screening at age 40. This change reflects evolving evidence that starting earlier screening yields greater net benefits in reducing breast cancer mortality, particularly for […]

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Can Weight Loss Drugs Also Treat Addiction?

Source link : https://www.newshealth.biz/health-news/can-weight-loss-drugs-also-treat-addiction/ A new study provides more evidence that glucagon-like peptide 1 receptor agonists (GLP-1 RAs) used to treat diabetes and obesity could be repurposed for opioid use disorder (OUD) and alcohol use disorder (AUD). Researchers found that patients with OUD or AUD who were taking semaglutide (Ozempic, Novo Nordisk) or similar medications […]

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No Excess MACE Risk for JAKis in Atopic Dermatitis Analysis

Source link : https://www.newshealth.biz/health-news/no-excess-mace-risk-for-jakis-in-atopic-dermatitis-analysis/ AMSTERDAM — Janus kinase inhibitors (JAKis) do not appear to increase the risk for major adverse cardiovascular events (MACE) among people with atopic dermatitis (AD) treated in a real-world setting, suggested the results of a large, US-based, retrospective cohort study. This holds true even in individuals aged 50 years or older, […]

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Clinicians Face Confusion on Lipid Screenings for Children

Source link : https://www.newshealth.biz/health-news/clinicians-face-confusion-on-lipid-screenings-for-children/ Clinicians receive conflicting advice on whether to order blood tests to screen for lipids in children. A new study could add to the confusion. Researchers found that a combination of physical proxy measures such as hypertension and body mass index (BMI) predicted the risk for future cardiovascular events as well as […]

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Numerous Industrial Products Are Found in the Human Body

Source link : https://www.newshealth.biz/health-news/numerous-industrial-products-are-found-in-the-human-body/ Materials that are in contact with food contain chemical substances that can migrate into food products and subsequently into the human body. Several of these substances have been studied, and the health risks that some of them pose have been well documented. One example is the well-known bisphenol A, which the […]

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Cendakimab Shows Promise in Eosinophilic Esophagitis

Source link : https://www.newshealth.biz/health-news/cendakimab-shows-promise-in-eosinophilic-esophagitis/ VIENNA — Cendakimab, a monoclonal antibody targeting interleukin (IL) 13, improved symptoms and reduced esophageal eosinophil counts in adult and adolescent patients with eosinophilic esophagitis (EoE), according to interim results of a pivotal phase 3 trial. Treatment with cendakimab also improved key endoscopic and histologic features, even in patients who had […]

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Maternal HS Tied to Adverse Outcomes in Children and Mothers

Source link : https://www.newshealth.biz/health-news/maternal-hs-tied-to-adverse-outcomes-in-children-and-mothers/ TOPLINE: Hidradenitis suppurativa (HS) in pregnant women is associated with increased risks for adverse pregnancy outcomes, including hypertensive disorders, gestational diabetes, and severe maternal morbidity, as well as higher neonatal risks such as preterm birth and birth defects. METHODOLOGY: Researchers conducted a population-based longitudinal cohort study in Quebec, Canada, from 2006 […]

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The Hidden Cost of Cancer Treatment: Time Toxicity

Source link : https://www.newshealth.biz/health-news/the-hidden-cost-of-cancer-treatment-time-toxicity/ TOPLINE: Older adults with metastatic cancer living in Mexico spend about 1 in 5 days during the initial months of treatment in contact with a healthcare provider, with a higher time burden for those receiving radiotherapy or cytotoxic chemotherapy and for frail individuals. METHODOLOGY: Time toxicity — days spent with healthcare […]

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7 Study Apps Help Med Students Prep for Exams

Source link : https://www.newshealth.biz/health-news/7-study-apps-help-med-students-prep-for-exams/ Struggling to stay on top of endless medical school information? There’s an app for that. With more medical students reinforcing their classroom lectures with virtual learning, students increasingly depend on digital study apps to help them absorb and retain vast amounts of complex medical information needed to pass licensing exams. Medscape […]

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How do drugs like Wegovy and Mounjaro work?

Source link : https://www.newshealth.biz/health-news/how-do-drugs-like-wegovy-and-mounjaro-work/ Getty The government has suggested weight-loss drugs could boost the economy by helping obese people in England get back to work. But NHS experts have warned treatment services are already overstretched trying to deal with unprecedented demand from patients wanting these drugs. How do Wegovy and Mounjaro work and how successful […]

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Breast cancer patients denied life-extending drug in NHS row

Source link : https://www.newshealth.biz/health-news/breast-cancer-patients-denied-life-extending-drug-in-nhs-row/ Jeannie Ambrose Jeannie Ambrose, one of about 1,000 affected patients, says Enhertu should be made available on the NHS More than a thousand patients with advanced breast cancer are being denied a drug that can keep them alive for longer. It is already available in 19 countries in Europe – including […]

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Continuous Parkinson’s Disease Therapy Wins FDA Nod

Source link : https://www.newshealth.biz/health-news/continuous-parkinsons-disease-therapy-wins-fda-nod/ The FDA approved a subcutaneous 24-hour continuous infusion of foscarbidopa and foslevodopa (Vyalev) for advanced Parkinson’s disease, AbbVie announced Thursday. Foscarbidopa and foslevodopa are pro-drugs for carbidopa and levodopa, which are standard-of-care Parkinson’s treatments. The new treatment, formerly know as ABBV-951, is the first subcutaneous 24-hour-a-day infusion of a levodopa-based therapy […]

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Study Offers Clues for Avoiding RMD Flares After COVID Vaccination

Source link : https://www.newshealth.biz/health-news/study-offers-clues-for-avoiding-rmd-flares-after-covid-vaccination/ Predicting which people with inflammatory rheumatic musculoskeletal diseases (I-RMDs) may experience flares after COVID-19 vaccination just got a bit easier, thanks to a new analysis of more than 7,000 European RMD patients. Factors associated with increased flare rates post-vaccination included active disease at the time, female sex, and — most strongly […]

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Air Pollution Risky After Lung Transplant

Source link : https://www.newshealth.biz/health-news/air-pollution-risky-after-lung-transplant/ For lung transplant recipients, exposure to higher air pollution levels was linked to an increased risk of death or graft failure, a retrospective cohort study found. Living in a zip code exposed to elevated ambient fine particulate matter levels was associated with an increased hazard of death or graft failure, with […]

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Hormonal IUDs Linked to Increased Breast Cancer Risk

Source link : https://www.newshealth.biz/health-news/hormonal-iuds-linked-to-increased-breast-cancer-risk/ Women younger than 50 who used a levonorgestrel-releasing intrauterine device (IUD) had a significantly higher risk of breast cancer as compared with women who did not use hormonal contraceptives, a Danish registry study showed. During follow-up of almost 7 years, hormone-releasing IUD use conferred a 40% higher risk of breast cancer. […]

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Pumpkin Safety Tips; Sleep MD Snoozing Tricks; What It’s Like to Date a Resident

Source link : https://www.newshealth.biz/health-news/pumpkin-safety-tips-sleep-md-snoozing-tricks-what-its-like-to-date-a-resident/ The following contains links to social media websites including X, TikTok, Instagram, Facebook, and LinkedIn. It’s pumpkin patch season, which means … potential back injuries? @ladyspinedoc showed her audience how to lift a pumpkin safely during fall festivities. “Parents, please do not be afraid of shopping carts.” In response to a […]

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New Estimates Show Over 4 Million People in the U.S. Have Glaucoma

Source link : https://www.newshealth.biz/health-news/new-estimates-show-over-4-million-people-in-the-u-s-have-glaucoma/ An estimated 4.22 million people in the U.S. had glaucoma and 1.49 million people had vision-affecting glaucoma in 2022, with Black adults approximately twice as likely as white adults to be affected, according to a meta-analysis. The prevalence of glaucoma was 1.62% among people ages 18 and older and 2.56% among […]

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Stroke Survivors Still Prescribed a ‘Concerning’ Amount of Benzos

Source link : https://www.newshealth.biz/health-news/stroke-survivors-still-prescribed-a-concerning-amount-of-benzos/ More vigilance may be needed regarding the amount of benzodiazepines being dispensed to older stroke survivors, though prescription patterns at the national level have improved in recent years. Medicare records showed that within 90 days of discharge following an acute ischemic stroke, 4.9% of patients 65 years or older initiated a […]

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How Unconventional Thinkers Unlock Medical Innovation

Source link : https://www.newshealth.biz/health-news/how-unconventional-thinkers-unlock-medical-innovation/ Murphy is a clinician, researcher, teacher, and inventor. Despite the uphill battle that most inventors must undertake to bring their innovations to market, the global market for medical device technologies was valued at $550 billion in 2021. By 2030, it is projected to reach $850 billion, reflecting a compound annual growth […]

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Medtronic Warns of Battery Problem With Insulin Pumps

Source link : https://www.newshealth.biz/health-news/medtronic-warns-of-battery-problem-with-insulin-pumps/ Medtronic has issued a second alert letter to patients regarding shortened battery life of the MiniMed 600 and 700 series insulin pumps.  The affected products include the MiniMed 630G, 670G, 770G, and 780G, all lots and serial numbers. The problem can arise when a pump is dropped, bumped, or otherwise physically […]

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As Election Nears, Trump Is Still Not Sharing Any Health Details

Source link : https://www.newshealth.biz/health-news/as-election-nears-trump-is-still-not-sharing-any-health-details/ If he wins next month’s election, Donald Trump would be the oldest person in U.S. history to be elected president. Yet the 78-year-old Republican nominee refuses to disclose new details about his physical or mental well-being, breaking decades of precedent. There have been limited snapshots of Trump’s health over the last […]

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FDA OKs Once-Nightly Lumryz for Children With Narcolepsy

Source link : https://www.newshealth.biz/health-news/fda-oks-once-nightly-lumryz-for-children-with-narcolepsy/ The US Food and Drug Administration (FDA) has approved Avadel Pharmaceuticals’ supplemental new drug application for extended-release sodium oxybate (Lumryz) for treatment of cataplexy or excessive daytime sleepiness in children 7 years of age and older with narcolepsy. The FDA first approved the once-nightly formulation of sodium oxybate for treatment of […]

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HIV-Positive Donors Safe for Kidney Transplants

Source link : https://www.newshealth.biz/health-news/hiv-positive-donors-safe-for-kidney-transplants/ Kidney transplant recipients with HIV who receive organs from HIV-positive donors show no worse safety outcomes compared with those receiving organs from donors without HIV, supporting a proposed change to allow such transplants beyond the current restrictions of research-only settings. “These results will have far-reaching effects in many countries that do […]

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Doc Sues Over Spicy Dish; Disciplined for Doctor’s Note; Ob/Gyn Attacked Near Office

Source link : https://www.newshealth.biz/health-news/doc-sues-over-spicy-dish-disciplined-for-doctors-note-ob-gyn-attacked-near-office/ California doctor Harjasleen Walia, MD, sued a Thai restaurant alleging that its “Dragon Balls” appetizer was so spicy it burned her vocal cords, esophagus, and the inside of her right nostril. The case is set to go to jury trial next year. (SiliconValley.com) Connecticut’s medical board has put a resident physician […]

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Europe’s Deep Dive Into Equitable Cancer Care

Source link : https://www.newshealth.biz/health-news/europes-deep-dive-into-equitable-cancer-care/ Romania faces significant challenges in cancer care, with high cancer mortality rates and limited access to comprehensive screening and treatment programs. “We desperately need to improve,” said Delia Nicoară, a public health specialist at The Oncology Institute “Prof. Dr Ion Chiricuta” in Cluj-Napoca, Romania, speaking to Medscape Medical News. Delia Nicoară […]

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Three States Renew Effort to Reduce Access to Abortion Pill Mifepristone

Source link : https://www.newshealth.biz/health-news/three-states-renew-effort-to-reduce-access-to-abortion-pill-mifepristone/ Three states are renewing a legal push to restrict access to the abortion medication mifepristone (Mifeprex), including reinstating requirements it be dispensed in person instead of by mail. The request from Kansas, Idaho, and Missouri filed Friday would bar the drug’s use after 7 weeks of pregnancy instead of 10 and […]

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SBRT or Surgery in Localized Prostate Cancer: Is One Better?

Source link : https://www.newshealth.biz/health-news/sbrt-or-surgery-in-localized-prostate-cancer-is-one-better/ TOPLINE: In patients with localized prostate cancer, stereotactic body radiotherapy (SBRT) was associated with better urinary continence and sexual function, but slightly worse bowel function, compared with radical prostatectomy, according to a phase 3 open-label, randomized trial evaluating quality-of-life outcomes. METHODOLOGY: Compared with prostatectomy, radiotherapy may offer better urinary and sexual […]

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Kids’ Neurodevelopment Appears Unharmed by Maternal COVID Infection

Source link : https://www.newshealth.biz/health-news/kids-neurodevelopment-appears-unharmed-by-maternal-covid-infection/ Exposure to maternal COVID-19 was not associated with abnormal neurodevelopmental screening results through 24 months’ postpartum, according to a cohort study in JAMA Network Open. In this video interview, researcher Eleni Greenwood Jaswa, MD, MSc, of the University of California San Francisco, discusses the study’s findings and implications. The following is […]

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Conversion Practices Tied to Worse Mental Health Outcomes

Source link : https://www.newshealth.biz/health-news/conversion-practices-tied-to-worse-mental-health-outcomes/ TOPLINE:  Conversion practices targeting gender identity or sexual orientation is associated with increased depression, posttraumatic stress disorder (PTSD), and suicidality in LGBTQ+ adults, a new study shows.  METHODOLOGY: Researchers analyzed data from the PRIDE study, a US-based, online, prospective cohort study of 4426 adults (57% cisgender, 43% transgender/gender diverse) who completed […]

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MDMA Is Off the Table, So What’s Next for PTSD?

Source link : https://www.newshealth.biz/health-news/mdma-is-off-the-table-so-whats-next-for-ptsd/ It has been 24 years since a pharmaceutical was last approved for posttraumatic stress disorder (PTSD). The condition is notoriously difficult to treat, with up to 40% patients finding no relief from symptoms through psychotherapy or current medications. Many clinicians, advocates, and patients had pinned their hopes on the psychedelic drug […]

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COVID Greatly Increases Diabetes Risk in Kids and Teens

Source link : https://www.newshealth.biz/health-news/covid-greatly-increases-diabetes-risk-in-kids-and-teens/ As the nation searches for ways to reduce the number of young people diagnosed with type 2 diabetes, a new prevention pathway is emerging: avoiding COVID-19. Teens and adolescents were much more likely to be newly diagnosed with type 2 diabetes within 6 months of having COVID-19, compared to kids of […]

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Mobile Clinics Provide Birth Control in Rural Areas

Source link : https://www.newshealth.biz/health-news/mobile-clinics-provide-birth-control-in-rural-areas/ Twice a month, a 40-foot-long truck transformed into a mobile clinic travels the Rio Grande Valley to provide rural Texans with women’s healthcare, including birth control. The clinic, called the UniMóvil, is part of the Healthy Mujeres program at the University of Texas Rio Grande Valley School of Medicine. The US […]

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Maternal COVID-19 May Not Harm Baby’s Neural Development

Source link : https://www.newshealth.biz/health-news/maternal-covid-19-may-not-harm-babys-neural-development/ TOPLINE: Fetuses exposed in utero to SARS-CoV-2 are not at an increased risk for neurodevelopmental problems in early childhood. METHODOLOGY: This prospective study aimed to assess whether in utero exposure to SARS-CoV-2, which causes COVID-19, is associated with abnormal neurodevelopment among children at ages 12, 18, and 24 months. It included […]

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Genetic Marker Tied to Severe Ulcerative Colitis Identified

Source link : https://www.newshealth.biz/health-news/genetic-marker-tied-to-severe-ulcerative-colitis-identified/ TOPLINE: VIENNA — Individuals with ulcerative colitis (UC) who carry the HLA-DRB1*01:03 allele are at increased risk of having a more severe disease course requiring major surgery, hospitalization, and high-dose systemic corticosteroids within 3 years of diagnosis, according to a Danish study. METHODOLOGY: Reliable biomarkers are lacking to identify patients with […]

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Pediatric Obesity and MASLD: A Risky Combination for T2D

Source link : https://www.newshealth.biz/health-news/pediatric-obesity-and-masld-a-risky-combination-for-t2d/ MASLD in pediatric obesity was linked to an increased risk for youth-onset type 2 diabetes, especially in the presence of intermediate hyperglycemia. Medscape Medical News Source link : https://www.medscape.com/viewarticle/pediatric-obesity-and-masld-risky-combination-t2d-2024a1000izi?src=rss Author : Publish date : 2024-10-17 11:58:57 Copyright for syndicated content belongs to the linked Source. Author : News Health Publish date […]

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The Heavy Physical and Psychological Burden of PMDD

Source link : https://www.newshealth.biz/health-news/the-heavy-physical-and-psychological-burden-of-pmdd/ Premenstrual disorders (PMDs), including premenstrual dysphoric disorder (PMDD), adversely affect the lives of millions of women worldwide. Most girls and women — as many as 80%-90%— will experience some premenstrual discomfort such as irritability, depressed mood, food or alcohol cravings, bloating, body aches, breast pain, constipation, or fatigue. Diagnosable menstrual disorders […]

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Novel Nerve Block Yields Benefits in Bariatric Surgery

Source link : https://www.newshealth.biz/health-news/novel-nerve-block-yields-benefits-in-bariatric-surgery/ Autonomic neural blockade may represent a unique way to manage postoperative visceral pain and associated symptoms following minimally invasive weight loss surgery, according to a new report in JAMA Surgery. The novel technique targets blockade of sympathetic and parasympathetic pathways by injecting local anesthetic into the areolar tissue surrounding selected autonomic […]

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Induction Chemotherapy Boosts Survival in Cervical Cancer

Source link : https://www.newshealth.biz/health-news/induction-chemotherapy-boosts-survival-in-cervical-cancer/ TOPLINE: Induction chemotherapy followed by chemoradiotherapy improves 5-year overall survival rates in advanced cervical cancer from 72% to 80%. The treatment also enhances 5-year progression-free survival rates from 64% to 72%. METHODOLOGY: Researchers conducted a multicenter, randomized phase 3 INTERLACE trial to evaluate whether short-course induction chemotherapy before chemoradiotherapy is more […]

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Treatment Is in Sight for Charcot-Marie-Tooth Disease

Source link : https://www.newshealth.biz/health-news/treatment-is-in-sight-for-charcot-marie-tooth-disease/ SAVANNAH, Georgia — There’s no medical treatment for Charcot-Marie-Tooth (CMT) disease, a debilitating neurologic disorder that’s both progressive and incurable. But now, nerve specialists learned, new potential treatments are moving closer to clinical trials. Genetic-based therapies are currently in preclinical research phases, and an experimental small-molecule drug has reached phase 3 […]

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First-in-Class B-Cell Depleting Agent Promising for MG

Source link : https://www.newshealth.biz/health-news/first-in-class-b-cell-depleting-agent-promising-for-mg/ SAVANNAH, Georgia — Inebilizumab, a first-in-class anti-CD19 B-cell depleting agent, demonstrated both safety and superior efficacy compared with placebo in patients with seropositive generalized myasthenia gravis (gMG), new phase 3 data showed. “Based on these results, we have demonstrated that targeting B cells, including the antibody-secreting cells, is beneficial, and there […]

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UPFs Associated With Relapse Risk in Crohn’s Disease

Source link : https://www.newshealth.biz/health-news/upfs-associated-with-relapse-risk-in-crohns-disease/ VIENNA — A diet high in ultraprocessed foods (UPFs) increases the risk for clinical relapse in patients with Crohn’s disease (CD) who are in remission, results of a new study suggested. Certain subgroups of UPFs, specifically bread, pastries, and starch as well as oil and spreads, exhibited the strongest association with […]

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T2D More Prevalent Than T1D Among Adolescents in Some Areas

Source link : https://www.newshealth.biz/health-news/t2d-more-prevalent-than-t1d-among-adolescents-in-some-areas/ In several countries, including China, Mexico, and the United States, the incidence of type 2 diabetes now exceeds that of type 1 diabetes among patients younger than 20 years. “This is an emerging epidemic,” said Orit Pinhas-Hamiel, MD, director of the Pediatric Endocrinology and Diabetes Unit at Sheba Medical Center in […]

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Women Less Likely to Receive, Take GDMT After Stroke

Source link : https://www.newshealth.biz/health-news/women-less-likely-to-receive-take-gdmt-after-stroke/ TOPLINE: Women with ischemic stroke are less likely than men with the condition to be prescribed guideline-directed medical therapies (GDMTs) within 30 days post-discharge. Women are also less likely than men to adhere to statins and antihypertensives at 1 year. METHODOLOGY: Researchers conducted a retrospective cohort analysis using the Truven Health […]

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Cambridge students undergo heart tests after hiker’s death

Source link : https://www.newshealth.biz/health-news/cambridge-students-undergo-heart-tests-after-hikers-death/ Hilary Nicholls Clarissa Nicholls collapsed and died while hiking in France Students at the University of Cambridge have been offered heart screenings after a 20-year-old undergraduate suffered a sudden cardiac arrest. Clarissa Nicholls collapsed and died from an undiagnosed arrhythmogenic cardiomyopathy (ACM) while hiking in France in May 2023. Miss Nicholls’ […]

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Chronic Skin Condition Tied to Host of Health Risks for Mother and Child

Source link : https://www.newshealth.biz/health-news/chronic-skin-condition-tied-to-host-of-health-risks-for-mother-and-child/ Maternal hidradenitis suppurativa (HS) was associated with complications during pregnancy as well as long-term maternal and child morbidity, a longitudinal cohort study from Canada showed. In the peripartum period, women with HS had a higher adjusted risk of hypertensive disorders of pregnancy (risk ratio [RR] 1.55, 95% CI 1.29-1.87), gestational diabetes […]

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Are Surgical Outcomes Better With MDs or DOs?

Source link : https://www.newshealth.biz/health-news/are-surgical-outcomes-better-with-mds-or-dos/ For Medicare patients, surgical outcomes were similar whether they had an MD or a DO surgeon, a claims analysis suggested. After adjusting for patient factors and practice settings, there was no difference in the primary outcome of 30-day mortality between MDs and DOs, with adjusted mortality rates of 1.58% and 1.61%, […]

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Lawmakers Pan DEA’s Leaked Plans for Telehealth

Source link : https://www.newshealth.biz/health-news/lawmakers-pan-deas-leaked-plans-for-telehealth/ Legislators who want to see an extension of COVID-era telemedicine flexibilities slammed a draft proposed rule from the Drug Enforcement Administration (DEA) that would curb telemedicine prescribing of controlled substances. Eleven senators, led by Sens. Sheldon Whitehouse (D-R.I.), Lisa Murkowski (R-Alaska), Mark Warner (D-Va.), and Marsha Blackburn (R-Tenn.), criticized the new […]

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Radioligand Shows Promise in Metastatic Hormone-Sensitive Prostate Cancer

Source link : https://www.newshealth.biz/health-news/radioligand-shows-promise-in-metastatic-hormone-sensitive-prostate-cancer/ In metastatic hormone-sensitive prostate cancer (mHSPC), adding the radioligand 177Lu-PSMA-617 (Pluvicto) to androgen deprivation therapy (ADT) and chemotherapy more than doubled biochemical recurrence-free survival (BRFS), the randomized UpFrontPSMA trial showed. BRFS at 48 weeks, defined as a prostate-specific antigen (PSA) value ≤0.2 ng/mL, increased from 16% with ADT and docetaxel to […]

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Nipocalimab Shows Sustained Efficacy in Myasthenia Gravis

Source link : https://www.newshealth.biz/health-news/nipocalimab-shows-sustained-efficacy-in-myasthenia-gravis/ SAVANNAH, Ga. — Investigational nipocalimab lessened disease severity in generalized myasthenia gravis (gMG), the phase III Vivacity-MG3 trial showed. The primary endpoint was the change in Myasthenia Gravis Activities of Daily Living (MG-ADL) scores from baseline to the average over weeks 22, 23, and 24 in seropositive patients with gMG. The […]

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People With HIV Can Safely Receive Kidneys From Donors With HIV

Source link : https://www.newshealth.biz/health-news/people-with-hiv-can-safely-receive-kidneys-from-donors-with-hiv/ Kidney transplantation from donors with HIV appeared to be noninferior to donors without HIV in terms of safety for recipients with HIV, an observational study indicated. Among 198 patients with HIV who received a kidney from a deceased donor, risk of a safety event within a median of 2.2 years was […]

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Nivolumab Regimen Achieves Durable PFS in Advanced Hodgkin’s Lymphoma

Source link : https://www.newshealth.biz/health-news/nivolumab-regimen-achieves-durable-pfs-in-advanced-hodgkins-lymphoma/ Adding nivolumab (Opdivo) instead of brentuximab vedotin (Adcetris) to the standard chemotherapy backbone of doxorubicin (Adriamycin), vinblastine, and dacarbazine (AVD) resulted in longer progression-free survival (PFS) in adolescents and adults with advanced-stage classic Hodgkin’s lymphoma, longer follow-up of the SWOG S1826 trial showed. Among 970 patients in the intention-to-treat population, the […]

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Novel Drug Maintained Clinical Improvements in IBD

Source link : https://www.newshealth.biz/health-news/novel-drug-maintained-clinical-improvements-in-ibd/ Patients with inflammatory bowel disease (IBD) who initially responded to the investigational monoclonal antibody tulisokibart continued to maintain clinical and endoscopic improvements through week 50, according to data from open-label extensions of a pair of phase II trials. In patients with ulcerative colitis, 48% of those receiving 250 mg of intravenous […]

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Want Electronic Reimbursement? That Will Cost You a 5% Fee.

Source link : https://www.newshealth.biz/health-news/want-electronic-reimbursement-that-will-cost-you-a-5-fee/ Soloman is a rheumatologist. If you’re like most Americans, you prefer to be paid electronically instead of with old-fashioned paper checks. But imagine if your employer forced you to pay a 2% to 5% processing fee out of each paycheck just for the convenience of directly receiving the money you’ve earned. […]

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No Single Antipsychotic Offers Cognitive Benefit in Schizophrenia Disorders

Source link : https://www.newshealth.biz/health-news/no-single-antipsychotic-offers-cognitive-benefit-in-schizophrenia-disorders/ No individual antipsychotic was associated with better cognitive outcomes than placebo in patients with schizophrenia spectrum disorders (SSD), according to a systematic review and network meta-analysis. However, the study revealed that two first-generation dopamine antagonists — haloperidol (standardized mean difference [SMD] 0.04, 95% CI −0.25 to 0.33) and fluphenazine (SMD 0.15, […]

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Sustained Control with New mAb for Myasthenia Gravis

Source link : https://www.newshealth.biz/health-news/sustained-control-with-new-mab-for-myasthenia-gravis/ SAVANNAH, GEORGIA – The investigational monoclonal antibody nipocalimab (Johnson & Johnson) is associated with significant improvement in patients with generalized myasthenia gravis (gMG) over a 24-week period, according to topline results from the phase 3 VIVACITY-MG3 study. The VIVACITY-MG3 trial is the first registrational study of a neonatal fragment crystallizable receptor […]

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15.5M Adults Have ADHD; Pediatric Social Media Harms; Loneliness Affects 1 in 5

Source link : https://www.newshealth.biz/health-news/15-5m-adults-have-adhd-pediatric-social-media-harms-loneliness-affects-1-in-5/ In 2023, an estimated 15.5 million U.S. adults had an attention deficit-hyperactivity disorder (ADHD) diagnosis; half were diagnosed in adulthood. (Morbidity and Mortality Weekly Report) And 25% of adults suspect they may have undiagnosed ADHD, according to a national survey of 1,000 Americans commissioned by the Ohio State University Wexner Medical […]

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Can Aerosolized Nut Particles on a Plane Really Cause an Allergic Reaction?

Source link : https://www.newshealth.biz/health-news/can-aerosolized-nut-particles-on-a-plane-really-cause-an-allergic-reaction/ One of the misconceptions about food allergies during air travel is that aerosolized nut particles circulate in the aircraft ventilation system and pose a significant risk, which could be mitigated by “nut bans,” according to an evidence review. Contrary to this common belief, allergic reactions during commercial air travel are actually […]

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California Health Workers Get a Pay Bump Under New Minimum Wage Law

Source link : https://www.newshealth.biz/health-news/california-health-workers-get-a-pay-bump-under-new-minimum-wage-law/ Some of the lowest-paid healthcare workers in California will get a pay bump Wednesday under a state law gradually increasing their wages to at least $25 an hour. Workers at rural, independent healthcare facilities will start making a minimum of $18 an hour, while others at hospitals with at least 10,000 […]

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Doc Befriends Captive Saudi Princess; Psych Hospital Violence; Black Market Ozempic

Source link : https://www.newshealth.biz/health-news/doc-befriends-captive-saudi-princess-psych-hospital-violence-black-market-ozempic/ Welcome to the latest edition of Investigative Roundup, highlighting some of the best investigative reporting on healthcare each week. Physician Befriended Captive Saudi Princess After years of working for the Saudi royal family, a physician from Texas realized his employers were keeping their daughters hostage — and that he was complicit, […]

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Private Forums Show Canadian Doctors Struggle With Euthanizing Vulnerable Patients

Source link : https://www.newshealth.biz/health-news/private-forums-show-canadian-doctors-struggle-with-euthanizing-vulnerable-patients/ TORONTO — A homeless man refusing long-term care, a woman with severe obesity, an injured worker given meager government assistance, and grieving new widows. All of them requested to be killed under Canada’s euthanasia system, and each sparked private debate among doctors and nurses struggling with the ethics of one of […]

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The Power of ‘And’ | MedPage Today

Source link : https://www.newshealth.biz/health-news/the-power-of-and-medpage-today/ David Nash is the Founding Dean Emeritus and Dr. Raymond C. and Doris N. Grandon Professor of Health Policy at the Jefferson College of Population Health. He is a board-certified internist. Follow I was very touched when my rabbi asked me to give a 10-minute presentation on the night before Yom […]

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GLP-1 RAs Reduce Suicidal Behavior in Adolescents

Source link : https://www.newshealth.biz/health-news/glp-1-ras-reduce-suicidal-behavior-in-adolescents/ Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) given to adolescents with obesity was associated with a one-third decreased risk for suicidal ideation and suicide attempts compared with lifestyle intervention alone, a large international retrospective study found. A study published on October 14, 2024, in JAMA Pediatrics suggested that GLP-1 RAs such […]

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The Supreme Court’s Open Season on Public Health Agencies

Source link : https://www.newshealth.biz/health-news/the-supreme-courts-open-season-on-public-health-agencies/ Jeremy Faust is editor-in-chief of MedPage Today, an emergency medicine physician at Brigham and Women’s Hospital in Boston, and a public health researcher. He is author of the Substack column Inside Medicine. Follow Emily Hutto is an Associate Video Producer & Editor for MedPage Today. She is based in Manhattan. In […]

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When Patients Defy All Odds

Source link : https://www.newshealth.biz/health-news/when-patients-defy-all-odds/ It was Christmas time when Heloisa Soares, MD, shuffled through a family crowding her 68-year-old patient’s hospital bed.  The prognosis wasn’t good.  Soares, a GI cancer specialist at Huntsman Cancer Institute in Salt Lake City, delivered the bad news: The patient had small-cell carcinoma of unknown origin, possibly the gynecology track. […]

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A Call to End Daylight Saving Time?

Source link : https://www.newshealth.biz/health-news/a-call-to-end-daylight-saving-time/ Katie Sullivan, DNP, FNP-C, is publicizing her own challenge with updating an insulin pump as part of an effort to bring an end to the biannual seasonal clock changes in the United States. On March 10, 2024, Sullivan, who works in the Endocrinology Clinic, Michigan State University, East Lansing, Michigan, mistakenly […]

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Automated Insulin Delivery Systems Reduce Burden in Diabetes

Source link : https://www.newshealth.biz/health-news/automated-insulin-delivery-systems-reduce-burden-in-diabetes/ TOPLINE:  Automated insulin delivery (AID) systems reduce diabetes distress and fear of hypoglycemia, improve quality of life, and increase awareness about hypoglycemia in adults, children, and adolescents with diabetes. METHODOLOGY:   Despite the known benefits of AID systems for glycemic control, conclusive evidence on the impact of these devices on person-reported […]

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Big AI Investment Means to Support Canada’s HCPs, Patients

Source link : https://www.newshealth.biz/health-news/big-ai-investment-means-to-support-canadas-hcps-patients/ In July, DIGITAL, Canada’s Global Innovation cluster for digital technologies, announced its largest-ever commitment to advancing artificial intelligence (AI) technologies for healthcare by funding more than one third of all costs for Health Compass II, a 4-year initiative to provide healthcare innovation and interoperability throughout the country. Health Compass II is a […]

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Hospitals Struggle With IV Fluid Shortages Post-Hurricane Helene

Source link : https://www.newshealth.biz/health-news/hospitals-struggle-with-iv-fluid-shortages-post-hurricane-helene/ When Hurricane Helene roared through North Carolina in September, the damage it caused went well beyond local homes and businesses. The North Cove-based manufacturing plant of Baxter International — the largest supplier of intravenous (IV) and peritoneal dialysis solutions in the United States — was “significantly impacted” in an unprecedented way […]

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Indigenous Patients Want Action After CMA’s Apology

Source link : https://www.newshealth.biz/health-news/indigenous-patients-want-action-after-cmas-apology/ Victor Summers died in May 2023. A member of Canada’s First Nations’ Oneida Tribe, Summers had been sober for 30 years, according to relatives such as his cousin Joel Abram, grand chief of the Association of Iroquois and Allied Indians and regional chief of the Oneida Nation of the Thames in […]

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I must keep working despite terminal diagnosis

Source link : https://www.newshealth.biz/health-news/i-must-keep-working-despite-terminal-diagnosis/ My Name’5 Doddie Foundation Scott Stewart keeps working in order to help support his daughter, Rae, with his wife, Robyn When Scott Stewart was diagnosed with motor neurone disease (MND), he knew he wanted to keep working to support his family. His reduced mobility meant he had to give up his […]

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Children With Severe AD Catch Up on Growth With Dupilumab

Source link : https://www.newshealth.biz/health-news/children-with-severe-ad-catch-up-on-growth-with-dupilumab/ AMSTERDAM — Children with short stature related to severe atopic dermatitis (AD) not only can have their condition effectively treated with 16 weeks of dupilumab but also may experience improved growth, bringing them back toward standard height curves, revealed a post hoc trial analysis. The research was presented at the European […]

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When It Comes to Polyp Diagnosis With CADx, Location Matters

Source link : https://www.newshealth.biz/health-news/when-it-comes-to-polyp-diagnosis-with-cadx-location-matters/ VIENNA — The effectiveness of computer-aided diagnosis (CADx) in differentiating neoplastic from non-neoplastic polyps depends on the region of the colon examined, according to a systematic review and meta-analysis. In particular, the diagnostic performance of CADx for polyps showed significantly lower specificity in the proximal colon than in the distal colon. […]

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