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FDA Approves Benralizumab for EGPA Vasculitis Indication

Source link : https://www.newshealth.biz/health-news/fda-approves-benralizumab-for-egpa-vasculitis-indication/ The US Food and Drug Administration (FDA) has approved benralizumab (Fasenra) for the treatment of adult patients with eosinophilic granulomatosis with polyangiitis (EGPA), formerly known as Churg-Strauss Syndrome. The drug is the second approved biologic for the treatment of EGPA. The first, mepolizumab (Nucala), was approved in 2017. “This disease has […]

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FDA OKs New Option for Rare Immune-Mediated Vasculitis

Source link : https://www.newshealth.biz/health-news/fda-oks-new-option-for-rare-immune-mediated-vasculitis/ The FDA approved the asthma drug benralizumab (Fasenra) as a new therapy for adults with eosinophilic granulomatosis with polyangiitis (EGPA), drugmaker AstraZeneca announced on Wednesday. EGPA, previously known as Churg-Strauss syndrome, is a rare inflammatory disorder characterized by asthma, necrotizing vasculitis, extravascular granulomas, and blood and tissue eosinophilia. The rare immune-mediated […]

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Abortion Ban Deaths; Trans Paper Retraction Fallout; The Payout That Drained Steward

Source link : https://www.newshealth.biz/health-news/abortion-ban-deaths-trans-paper-retraction-fallout-the-payout-that-drained-steward/ Welcome to the latest edition of Investigative Roundup, highlighting some of the best investigative reporting on healthcare each week. Georgia Abortion Ban Linked to Two Deaths Georgia’s maternal mortality committee concluded that the deaths of two women who didn’t receive adequate care for complications of medication abortion were preventable, according to […]

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Man Who Sold Fentanyl-Laced Pill Liable for $5.8 Million in Death of Young Woman

Source link : https://www.newshealth.biz/health-news/man-who-sold-fentanyl-laced-pill-liable-for-5-8-million-in-death-of-young-woman/ In 2019, Brandon McDowell was contacted by a sophomore in college who asked to buy oxycodone-acetaminophen (Percocet), a prescription painkiller. What the 20-year-old sold her instead were counterfeit pills laced with fentanyl, a deadly synthetic opioid that can be lethal in a dose as small as 2 mg. Hours later, Alexandra […]

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Long Before I Was a Doctor, I was Just a Teen Whose Cousin Was Shot Dead

Source link : https://www.newshealth.biz/health-news/long-before-i-was-a-doctor-i-was-just-a-teen-whose-cousin-was-shot-dead/ Dark is an emergency medicine physician and professor. Long before I was an emergency physician and a medical educator with an alphabet soup of letters after my name, I was a nerdy, four-eyed teenager whose cousin was shot dead. I didn’t know much about trauma then. I knew about SATs and […]

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The Importance of Putting Penicillin Allergy Labels to the Test

Source link : https://www.newshealth.biz/health-news/the-importance-of-putting-penicillin-allergy-labels-to-the-test/ Rates of patient reactions to direct penicillin challenges are infrequent and comparable to indirect challenges after allergy testing, according to a meta-analysis in JAMA Internal Medicine. In this exclusive video interview, study author Kimberly Blumenthal, MD, MSC, of Harvard Medical School and Massachusetts General Hospital in Boston, discusses the research and […]

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Senate Republicans Again Block Legislation to Guarantee Women’s Rights to IVF

Source link : https://www.newshealth.biz/health-news/senate-republicans-again-block-legislation-to-guarantee-womens-rights-to-ivf/ Republicans have blocked for a second time this year legislation to establish a nationwide right to in vitro fertilization (IVF), arguing that the vote is an election-year stunt after Democrats forced a vote on the issue. The Senate vote was Democrats’ latest attempt to force Republicans into a defensive stance on […]

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Families waited eight years for full report on Letby unit

Source link : https://www.newshealth.biz/health-news/families-waited-eight-years-for-full-report-on-letby-unit/ A report about the neonatal unit where Lucy Letby worked was only shown to parents in full eight years after it was written, a public inquiry has heard. An external review was commissioned in September 2016 after consultants at the Countess of Chester Hospital voiced their concerns about the serial killer. […]

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Study calls on government to shrink pints

Source link : https://www.newshealth.biz/health-news/study-calls-on-government-to-shrink-pints/ A sobering discovery has led to Cambridge University academics calling on the government to stop serving beer in pints to reduce Britain’s alcohol intake. A study found that beer consumption dropped by 10% when pubs shelved pint glasses and served customers with glasses two thirds the size instead. That could be […]

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Concussion concerns raised by doctors

Source link : https://www.newshealth.biz/health-news/concussion-concerns-raised-by-doctors/ Icon Sportswire / Contributor Ron “Wolverine” Bata slapped Damien “The Bell” Dibbell in a five-round bout in Las Vegas in 2023 Doctors are worried a combat sport called slap fighting, watched by millions online and gaining in popularity, is causing serious brain damage. Competitors face off and take turns to deliver […]

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Study finds early puberty linked to higher risk for HS

Source link : https://www.newshealth.biz/health-news/study-finds-early-puberty-linked-to-higher-risk-for-hs/ TOPLINE: The prevalence of early onset of puberty was higher in children with hidradenitis suppurativa (HS) than those without HS, in a study that found precocious puberty increased the odds of developing HS by more than twofold. METHODOLOGY: In this case-control study, the researchers used data from the Explorys database, which […]

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Coffee and Heart, Metabolic Risks; What Drives Doctors Away; Ozempic for $100?

Source link : https://www.newshealth.biz/health-news/coffee-and-heart-metabolic-risks-what-drives-doctors-away-ozempic-for-100/ Note that some links may require registration or subscription. Habitual moderate coffee consumption — 200-300 mg of caffeine/day — was tied to a lower risk of cardiometabolic multimorbidity, a U.K. Biobank analysis found. (Journal of Clinical Endocrinology & Metabolism) The U.S. has seen a sudden drop in overdose deaths after decades […]

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CGM Cuts Hospitalization in T2D, Even in Non-Insulin Treated

Source link : https://www.newshealth.biz/health-news/cgm-cuts-hospitalization-in-t2d-even-in-non-insulin-treated/ MADRID — The use of continuous glucose monitoring (CGM) reduced the risk for hospitalization and improved glucose control in people with type 2 diabetes, regardless of insulin use, a new analysis of real-world data found. The data were presented at the European Association for the Study of Diabetes (EASD) 2024 Annual […]

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No Cancer Drug Delivery to Patients’ Homes

Source link : https://www.newshealth.biz/health-news/no-cancer-drug-delivery-to-patients-homes/ In late August, a federal judge ruled that a Medicare policy, which essentially prohibits oncology practices from delivering medications to patients at home, can stand. Some experts are concerned that leaving this Medicare policy in place will threaten access to cancer drugs for many patients, especially older individuals. The US District Court […]

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Overall Survival Data Confirm Benefit of Pembro in TNBC

Source link : https://www.newshealth.biz/health-news/overall-survival-data-confirm-benefit-of-pembro-in-tnbc/ BARCELONA, Spain — Long-awaited overall survival data from the KEYNOTE-522 trial has lifted spirits in the triple-negative breast cancer (TNBC) community.  The trial confirmed the survival benefit of adding perioperative pembrolizumab to standard chemotherapy in stage II or III disease. “We reduced the risk of death by 34%, which is the […]

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No QoL Downside With Adding Nivo to Chemo in Urothelial Cancer

Source link : https://www.newshealth.biz/health-news/no-qol-downside-with-adding-nivo-to-chemo-in-urothelial-cancer/ BARCELONA, Spain — Health-related quality of life (HRQoL) is not further compromised by the addition of nivolumab (Opdivo) immunotherapy to first-line cisplatin-based chemotherapy in patients with unresectable or metastatic urothelial carcinoma, according to an analysis of a phase 3 randomized trial. Jens Bedke, MD, presented this and other findings of the […]

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E-cigarette Use May Alter Healthy Nasal Mucosa

Source link : https://www.newshealth.biz/health-news/e-cigarette-use-may-alter-healthy-nasal-mucosa/ E-cigarette users and smokers had significantly higher amounts of Staphylococcus aureus in their respiratory microbiome than nonsmokers, and microbial diversity differed by sex, according to a new analysis. Researchers in a new study also found that Lactobacillus iners, usually seen as a protective species, was more prevalent in smokers than in nonsmokers, […]

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Are Women Underrepresented as Authors in Rheumatology RCTs?

Source link : https://www.newshealth.biz/health-news/are-women-underrepresented-as-authors-in-rheumatology-rcts/ TOPLINE:  Women are underrepresented as authors in randomized controlled trials (RCTs) published in rheumatology from 2009 to 2023. RCTs from Africa had higher women representation as authors, while RCTs from Asia and Europe and industry-funded RCTs had lower representation of women. METHODOLOGY: Researchers analyzed 1092 RCTs published in rheumatology from 2009 […]

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Your Cancer Patient’s Sexual Well-Being Really Matters

Source link : https://www.newshealth.biz/health-news/your-cancer-patients-sexual-well-being-really-matters/ BARCELONA — Oncologists struggle to discuss fertility and sexual health with patients, and the tools available to qualitatively and quantitatively assess these aspects are limited. This was highlighted during a session titled, “Oncofertility: What Every Health Professional Involved in Cancer Care Should Know,” held here at the 2024 annual meeting of […]

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Over One Third Develop EPI After Acute Pancreatitis

Source link : https://www.newshealth.biz/health-news/over-one-third-develop-epi-after-acute-pancreatitis/ TOPLINE: Over one third of patients with acute pancreatitis develop exocrine pancreatic insufficiency (EPI) at 12 months, with the key predictors being idiopathic etiology, moderately severe or severe disease, and preexisting diabetes. METHODOLOGY: EPI has traditionally been associated with chronic pancreatitis, but its prevalence and natural history following acute pancreatitis are […]

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Guidance Will Aid Pediatric to Adult Diabetes Care Transfer

Source link : https://www.newshealth.biz/health-news/guidance-will-aid-pediatric-to-adult-diabetes-care-transfer/ MADRID — A new consensus statement in development will aim to advise on best practices for navigating the transition of youth with diabetes from pediatric to adult diabetes care, despite limited data. Expected to be released in early 2025, the statement will be a joint effort of the International Society for […]

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Organ Preservation Strategy Shows Promise in Rectal Cancer

Source link : https://www.newshealth.biz/health-news/organ-preservation-strategy-shows-promise-in-rectal-cancer/ Organ preservation may be a viable option for select patients with locally advanced rectal cancer, according to the first results of the NO-CUT trial. The study investigated the efficacy of total neoadjuvant treatment followed by nonoperative management in patients with proficient mismatch repair (pMMR) locally advanced rectal cancer. Alessio Amatu, MD, […]

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Adjuvant Aspirin Trial in CRC Inconclusive

Source link : https://www.newshealth.biz/health-news/adjuvant-aspirin-trial-in-crc-inconclusive/ BARCELONA, Spain — A higher disease-free survival (DFS) rate was seen for patients with stage II/III colon cancer given adjuvant aspirin than for those given placebo in a randomized, double-blinded study. Ulrich Güller, MD, Kantonsspital St.Gallen, St.Gallen, Switzerland, presented the results of the phase 3, Swiss SAKK 41/13 trial, involving patients […]

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Abortion safe zones coming into force on 31 October, says Home Office

Source link : https://www.newshealth.biz/health-news/abortion-safe-zones-coming-into-force-on-31-october-says-home-office/ Buffer zones will come into force around abortion clinics in England and Wales from 31 October. It will make it illegal to hand out anti-abortion leaflets within the buffer zone or obstruct anyone using or working at an abortion clinic. The protection zones, which will prohibit protest, will extend to a […]

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Controlling Six Risk Factors Can Combat CKD in Obesity

Source link : https://www.newshealth.biz/health-news/controlling-six-risk-factors-can-combat-ckd-in-obesity/ TOPLINE: Optimal management of blood pressure, A1c levels, low-density lipoprotein cholesterol (LDL-C), albuminuria, smoking, and physical activity may reduce the excess risk for chronic kidney disease (CKD) typically linked to obesity. The protective effect is more pronounced in men, in those with lower healthy food scores, and in users of diabetes […]

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Pivotal Trials Will Address Diversity With New FDA Initiative

Source link : https://www.newshealth.biz/health-news/pivotal-trials-will-address-diversity-with-new-fda-initiative/ NEW YORK — Underrepresentation by gender and race in major clinical trials has been a cause for complaint for decades, but the US Food and Drug Administration (FDA) has drafted a regulatory solution to this issue expected to be implemented sometime in 2025. This initiative, known as the FDA’s Diversity Action […]

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Seborrheic Dermatitis Progress Meaningful for Skin of Color

Source link : https://www.newshealth.biz/health-news/seborrheic-dermatitis-progress-meaningful-for-skin-of-color/ New York — Seborrheic dermatitis (SD) is a common and shared disorder across populations, but it is the third most common dermatologic complaint that Black individuals bring to the dermatologist and deserves more attention not only in this group but also overall, now that there is an approved therapy with an […]

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Quick BP, Smoking Interventions Make Mark in Rheum Clinics

Source link : https://www.newshealth.biz/health-news/quick-bp-smoking-interventions-make-mark-in-rheum-clinics/ Two relatively simple interventions — addressing high blood pressure (BP) and smoking cessation — could make a huge difference for patients with rheumatic disease. Patients with autoimmune disease are up to three times more likely to develop cardiovascular disease (CVD) than the general population. In addition to compounding CVD, smoking is […]

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One Dose of MVA-BN Moderately Effective Against Mpox

Source link : https://www.newshealth.biz/health-news/one-dose-of-mva-bn-moderately-effective-against-mpox/ A single dose of modified vaccinia Ankara–Bavarian Nordic (MVA-BN) vaccine is moderately effective in preventing mpox infection, according to findings from an emulated target trial. Analyzing information from several databases that included some 9800 adult men in Ontario, Canada, researchers found that one dose of MVA-BN was almost 60% effective in […]

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FDA Faces Blowback Over Regulating Lab-Developed Tests

Source link : https://www.newshealth.biz/health-news/fda-faces-blowback-over-regulating-lab-developed-tests/ The US Food and Drug Administration (FDA) plans to scrutinize the safety and efficacy of lab-developed tests — those designed, manufactured, and used in a single laboratory — far more thoroughly in the future. Under a rule finalized in April, the FDA will treat facilities that develop and use lab tests […]

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Biomarkers in Cord Blood May Predict AD in Newborns

Source link : https://www.newshealth.biz/health-news/biomarkers-in-cord-blood-may-predict-ad-in-newborns/ TOPLINE: Newborns who go on to develop atopic dermatitis (AD) show higher transepidermal water loss (TEWL) and cord blood serum levels of CCL17/thymus- and activation-regulated chemokine (TARC) and interleukin (IL) 31. METHODOLOGY: Researchers conducted a prospective study to evaluate the predictive role of serologic biomarkers and cutaneous markers and the development […]

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Junior doctors given job-title change BMA requested

Source link : https://www.newshealth.biz/health-news/junior-doctors-given-job-title-change-bma-requested/ Dr Lily Huang Dr Lily Huang, who works in London, supports the name change Junior doctors working across the NHS will now be called resident doctors instead – in a change intended to better reflect their expertise. The doctors union, the British Medical Association (BMA), which called for the change, called […]

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4 Key Factors Affect How Much Weight You Lose on GLP-1 Drugs

Source link : https://www.newshealth.biz/health-news/4-key-factors-affect-how-much-weight-you-lose-on-glp-1-drugs/ Share on PinterestFour key factors can greatly impact how much weight people lose while taking GLP-1 drugs like Ozempic, Wegovy, Victoza, and Saxenda. Daniel Llao Calvet/Getty Images Researchers have used real-world data to identify key factors for long-term weight loss for patients taking GLP-1 drugs like Ozempic and Wegovy. The study […]

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Lymphedema Risk No Higher With 3-Week RT Regimen in Early Breast Cancer

Source link : https://www.newshealth.biz/health-news/lymphedema-risk-no-higher-with-3-week-rt-regimen-in-early-breast-cancer/ A shorter radiotherapy (RT) course proved its mettle in early-stage breast cancer in terms of lymphedema risk, without negatively impacting survival outcomes, according to a phase III trial from France. In the HypoG-01 study, a 3-week course of moderately hypofractionated locoregional RT was noninferior to 5 weeks of normofractionated RT for […]

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CBT Improved Sex Life For Peri- and Post-Menopausal Women

Source link : https://www.newshealth.biz/health-news/cbt-improved-sex-life-for-peri-and-post-menopausal-women/ CHICAGO — Peri- and post-menopausal women who had cognitive behavioral therapy (CBT) for sexual concerns reported improvements in a range of symptoms after four sessions, according to a small trial. Results included a significant change in overall score on the Female Sexual Function Index (FSFI; Cohen’s d 0.87, P Author : […]

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Eye Drop Company in FDA’s Sights Once Again

Source link : https://www.newshealth.biz/health-news/eye-drop-company-in-fdas-sights-once-again/ The FDA has sent another letter — this time a warning letter — to a company that it previously flagged for marketing amniotic fluid eye drops. In a letter to Carl Harrell, MD, CEO of Regenerative Processing Plant in Palm Harbor, Florida, the agency said the company’s Regener-Eyes Pro and Regener-Eyes […]

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FDA Expands Approval of Ribociclib to Early Breast Cancer

Source link : https://www.newshealth.biz/health-news/fda-expands-approval-of-ribociclib-to-early-breast-cancer/ The FDA on Tuesday approved ribociclib (Kisqali) in combination with endocrine therapy as adjuvant treatment for early high-risk breast cancer. Already approved in the metastatic setting, the CDK4/6 inhibitor is now also indicated for patients with stages II-III disease who have hormone receptor (HR)-positive/HER2-negative tumors and a high risk for recurrence […]

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‘Failing Wisely’ Can Promote a Safer Healthcare System

Source link : https://www.newshealth.biz/health-news/failing-wisely-can-promote-a-safer-healthcare-system/ Fleisher is a professor emeritus of Anesthesiology and Critical Care. Edmondson is a professor of Leadership and Management. The Institute of Medicine (IOM) published To Err is Human 24 years ago with a call for the healthcare community to focus on patient safety. Despite widespread attention to the report, improvements in […]

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Survival Win for Pembrolizumab in Early Triple-Negative Breast Cancer

Source link : https://www.newshealth.biz/health-news/survival-win-for-pembrolizumab-in-early-triple-negative-breast-cancer/ PD-1 inhibition before and after surgery for high-risk early triple-negative breast cancer (TNBC) led to significant improvement in overall survival (OS), according to updated results from a large randomized trial. After a median follow-up of 75 months, the 5-year OS was 86.6% in patients who received pembrolizumab (Keytruda) before and after […]

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Cabozantinib Improves PFS for Advanced Neuroendocrine Tumors

Source link : https://www.newshealth.biz/health-news/cabozantinib-improves-pfs-for-advanced-neuroendocrine-tumors/ Cabozantinib (Cabometyx) significantly improved progression-free survival (PFS) in patients with previously treated, progressive advanced extrapancreatic or pancreatic neuroendocrine tumors (NETs), according to final results from the phase III CABINET trial. In the group of 203 patients with extrapancreatic NETs, the median PFS was 8.4 months with cabozantinib compared with 3.9 months […]

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Brain Training and Memory Decline; Alzheimer’s Pioneer Dies; Notorious APOE4

Source link : https://www.newshealth.biz/health-news/brain-training-and-memory-decline-alzheimers-pioneer-dies-notorious-apoe4/ In a 5-year follow-up study, cognitive training reduced memory decline in people with mild cognitive impairment. (Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring) Subcutaneous ocrelizumab and hyaluronidase (Ocrevus Zunovo) was approved for relapsing and progressive multiple sclerosis, Genentech said. The OCARINA II study supported the FDA’s decision. Erenumab (Aimovig) induced […]

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Here Are the Best Private Healthcare Companies to Work For

Source link : https://www.newshealth.biz/health-news/here-are-the-best-private-healthcare-companies-to-work-for/ U.S. News & World Report has released its list of the best private companies to work for, including in healthcare. While the field of healthcare recently has been plagued by worker burnout and poor mental health, 23 healthcare entities made the list, ranging from those providing health insurance, to medical care […]

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First Drug OK’d for Chronic Rhinosinusitis With Nasal Polyps in Adolescents

Source link : https://www.newshealth.biz/health-news/first-drug-okd-for-chronic-rhinosinusitis-with-nasal-polyps-in-adolescents/ The FDA broadened dupilumab’s (Dupixent) approval as an add-on maintenance treatment for chronic rhinosinusitis with nasal polyps to include adolescents as well, Regeneron Pharmaceuticals announced. With the expended indication, the interleukin (IL-4) receptor alpha antagonist is approved for use in children ages 12 to 17 years with inadequately controlled disease, making […]

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Coffee, Caffeine May Protect Cardiometabolic Health

Source link : https://www.newshealth.biz/health-news/coffee-caffeine-may-protect-cardiometabolic-health/ Share on PinterestModerate caffeine consumption may protect heart health and lower your risk of metabolic diseases. FG Trade/Getty Images New research suggests consuming three cups of coffee or 200–300 mg of caffeine daily may reduce the risk of developing cardiometabolic diseases compared to consuming little to none. Caffeine may improve cardiometabolic […]

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FDA Clears First 1-Year Continuous Glucose Sensor 

Source link : https://www.newshealth.biz/health-news/fda-clears-first-1-year-continuous-glucose-sensor/ The US Food and Drug Administration (FDA) has cleared the Eversense 365 (Senseonics), an implanted continuous glucose monitoring (CGM) system that lasts a year.  The Eversense is inserted subcutaneously into the upper arm by a certified healthcare professional during a brief office procedure. The transmitter is placed on the skin on […]

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Controversial Hungarian Gets EU Health Portfolio Nomination

Source link : https://www.newshealth.biz/health-news/controversial-hungarian-gets-eu-health-portfolio-nomination/ European Commission (EC) President Ursula von der Leyen has appointed Olivér Várhelyi as commissioner for health and animal welfare for the next 5 years. Whether he takes the portfolio depends on the European Parliament. There, committees are due to hold extensive hearings before a parliamentary vote on the entire commission. Várhelyi […]

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Lp(a) Cutoffs by Sex; LBBA Pacing Approvals; Loneliness Not to Blame for CVD?

Source link : https://www.newshealth.biz/health-news/lpa-cutoffs-by-sex-lbba-pacing-approvals-loneliness-not-to-blame-for-cvd/ Study suggests men and women need distinct lipoprotein(a), or Lp(a), cutoffs to characterize their risk of heart disease. (Clinical Cardiology) Moderate coffee drinkers were at a relatively lower risk of developing co-existing cardiometabolic diseases. (Journal of Clinical Endocrinology & Metabolism) A group lifestyle intervention tailored for U.S. South Asian communities had […]

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Adjuvant Atezolizumab Plus Bevacizumab Strike Out in HCC

Source link : https://www.newshealth.biz/health-news/adjuvant-atezolizumab-plus-bevacizumab-strike-out-in-hcc/ The initial results of the IMbrave050 trial raised hopes that an effective adjuvant regimen for hepatocellular carcinoma (HCC) might finally have arrived.  Patients with HCC treated with a combination of the immune checkpoint inhibitor atezolizumab and angiogenesis inhibitor bevacizumab after resection or ablation showed a 28% improvement in recurrence-free survival at […]

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Nurses bore the brunt of Covid, former chief nurse says

Source link : https://www.newshealth.biz/health-news/nurses-bore-the-brunt-of-covid-former-chief-nurse-says/ BBC Dame Ruth May was England’s chief nurse from 2019 until she retired in July 2024 Nurses bore the brunt of the pandemic, with low staffing levels and difficulties accessing protective equipment, according to England’s former chief nurse. Dame Ruth May told the Covid inquiry the NHS had been understaffed in […]

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Over Half of Adults With Uncontrolled Hypertension Unaware of Their Condition

Source link : https://www.newshealth.biz/health-news/over-half-of-adults-with-uncontrolled-hypertension-unaware-of-their-condition/ More than half of U.S. adults with uncontrolled hypertension are unaware they have hypertension in the first place, according to a recent study in JAMA Network Open. Furthermore, more than two-thirds of those on treatment had hypertension that remained uncontrolled. In this video interview, study author Adam Vaughan, PhD, MPH, of […]

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Snoring isn’t just a nuisance, it’s dangerous. Why can’t we treat it?

Source link : https://www.newshealth.biz/health-news/snoring-isnt-just-a-nuisance-its-dangerous-why-cant-we-treat-it/ Martin Parr/Magnum Photos It has ruined many a night’s sleep, and no doubt a lot of relationships too. Trying to sleep next to a snoring partner is exactly that: trying. Once the engines fire up, there are few countermeasures besides a shove, earplugs and the patience of a saint. That’s the […]

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Digital Breast Tomosynthesis May Reduce Development of Advanced Cancers

Source link : https://www.newshealth.biz/health-news/digital-breast-tomosynthesis-may-reduce-development-of-advanced-cancers/ Digital breast tomosynthesis (DBT) increased breast cancer detection rates and showed invasive cancers with a lower rate of advanced cancers compared with digital mammography, according to results from a retrospective study. In the review of 272,938 screenings for breast cancer, DBT had a higher cancer detection rate than digital mammography (5.3 […]

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Novel Plant-Based Estrogen Cuts Menopause Symptoms

Source link : https://www.newshealth.biz/health-news/novel-plant-based-estrogen-cuts-menopause-symptoms/ CHICAGO — Daily treatment with a plant-based form of estrogen significantly eased vasomotor symptoms (VMS) in postmenopausal women, the primary efficacy analysis of a phase III trial showed. In the so-called E4Comfort II study, two different doses of oral estetrol (E4) reduced the frequency of moderate to severe VMS versus placebo […]

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AAD Reading Room | Guidance for Safe Use of DEET in Children

Source link : https://www.newshealth.biz/health-news/aad-reading-room-guidance-for-safe-use-of-deet-in-children/ A review in Pediatric Dermatology provides an overview of current evidence on the safe use of the popular insect repellent N, N-diethyl-3 meta-toluamide (DEET) in children. It outlines pediatric recommendations relating to DEET and federally approved and naturally-derived DEET alternatives that provide similar protection at a lower toxicity. First author, Helana […]

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Taking on Inequities in Pediatric Respiratory Care

Source link : https://www.newshealth.biz/health-news/taking-on-inequities-in-pediatric-respiratory-care/ VIENNA — Health disparities have lasting effects on children’s respiratory health, but action at the community level can make a difference, according to experts in a session on diversity, equity, and inclusion in the pediatric asthma field at the European Respiratory Society (ERS) 2024 International Congress. Community-Level Challenges Health disparity is […]

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Untreated Brain Aneurysms Raise Mental Illness Risk

Source link : https://www.newshealth.biz/health-news/untreated-brain-aneurysms-raise-mental-illness-risk/ Untreated unruptured intracranial aneurysms were linked to a 10% higher risk for mental illness, especially among younger people and those requiring psychotherapy. Medscape Medical News Source link : https://www.medscape.com/viewarticle/untreated-brain-aneurysms-raise-mental-illness-risk-2024a1000gva?src=rss Author : Publish date : 2024-09-17 14:40:36 Copyright for syndicated content belongs to the linked Source. Author : News Health Publish date […]

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Locally Acquired Dengue Case Confirmed in California

Source link : https://www.newshealth.biz/health-news/locally-acquired-dengue-case-confirmed-in-california/ A case of locally acquired dengue fever has been confirmed in a resident of Baldwin Park, California, according to a press release from the Los Angeles County Department of Public Health. This locally acquired case of dengue is the third to be reported in California and the first to be reported […]

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Why Many Women Opt for a Double Mastectomy

Source link : https://www.newshealth.biz/health-news/why-many-women-opt-for-a-double-mastectomy/ Susan Derwin saw a call coming in. She had turned 60 that day, but this would not be a celebratory message.  It was her doctor’s office calling, with results from her routine screening mammogram. Derwin was told the scan had picked up something in her left breast, and she would need […]

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Antipsychotics Tied to Severe Respiratory Infection Risk

Source link : https://www.newshealth.biz/health-news/antipsychotics-tied-to-severe-respiratory-infection-risk/ TOPLINE: Antipsychotic use for schizophrenia or other psychotic disorders is associated with increased risk for severe COVID-19 or other respiratory infection and related hospitalization, a new retrospective study suggests. However, there was no link between antipsychotic use and mild infection outcomes.  METHODOLOGY: Researchers analyzed data from several Danish registries on 85,083 […]

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Durvalumab Boosts Survival in Muscle-Invasive Bladder Cancer

Source link : https://www.newshealth.biz/health-news/durvalumab-boosts-survival-in-muscle-invasive-bladder-cancer/ BARCELONA — Adding the immune checkpoint inhibitor durvalumab to standard treatment for muscle-invasive bladder cancer (MIBC) significantly improved survival, reducing the risk for death by 25%, according to a preplanned interim analysis of the phase 3 NIAGARA trial. These results offer practice-changing evidence in an area of unmet need, said lead […]

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Breastfeeding Safely Is Possible Following Breast Cancer

Source link : https://www.newshealth.biz/health-news/breastfeeding-safely-is-possible-following-breast-cancer/ BARCELONA, Spain — Breastfeeding is possible even after breast cancer, according to findings from two international studies led by Italian researchers, presented at the European Society for Medical Oncology (ESMO) Annual Meeting 2024. “Before this data, doctors tended to be cautious, if not outright defensive, about the possibility and safety of […]

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Daiichi Sankyo-Merck’s Cancer Drug Meets Main Goal in Late-stage Trial

Source link : https://www.newshealth.biz/health-news/daiichi-sankyo-mercks-cancer-drug-meets-main-goal-in-late-stage-trial/ (Reuters) -Daiichi Sankyo and Merck said on Tuesday that their drug, patritumab deruxtecan, met the main goal in a late-stage study in some patients with a type of lung cancer. The drug helped patients live significantly longer without their cancer progressing, compared with patients who were treated with chemotherapy, the companies […]

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Valley Fever Risk Uptick With Drought Conditions

Source link : https://www.newshealth.biz/health-news/valley-fever-risk-uptick-with-drought-conditions/ The western United States is experiencing an uptick in Valley fever, an often asymptomatic disease, that may increase in response to climate change-related drought, according to some experts. As dry conditions continue, California residents and travelers to California’s Central Valley or Central Coast regions may need to remain vigilant for an […]

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Short Steroid Treatment May Raise Diabetes Risk: Study

Source link : https://www.newshealth.biz/health-news/short-steroid-treatment-may-raise-diabetes-risk-study/ People who received systemic glucocorticoids during short hospital stays were more than twice as likely to develop new onset diabetes than those who didn’t, reported the authors of a large study that analyzed more than a decade’s worth of patient records. Rajna Golubic, MD, PhD, of the diabetes trials unit at […]

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When You and Your Malpractice Insurer Disagree on Your Case

Source link : https://www.newshealth.biz/health-news/when-you-and-your-malpractice-insurer-disagree-on-your-case/ You’ve been sued for medical malpractice. If you are a physician in the United States, that is not an unlikely scenario. An analysis by the American Medical Association shows that almost half of all physicians are sued by the time they reach 54. In some specialties, such as OB/GYN, one is […]

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Pembrolizumab Plus CCRT Improves Overall Survival

Source link : https://www.newshealth.biz/health-news/pembrolizumab-plus-ccrt-improves-overall-survival/ BARCELONA, Spain — Adding pembrolizumab to standard concurrent chemoradiotherapy (CCRT) significantly improves overall survival in patients with high-risk, locally advanced cervical cancer, according to results of a phase 3, randomized, double-blind trial. Domenica Lorusso, MD, PhD, director of Gynecological Oncology at Humanitas San Pio X and professor at Humanitas University, Milan, […]

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Adenosine Safe for Pediatric Tachyarrhythmia

Source link : https://www.newshealth.biz/health-news/adenosine-safe-for-pediatric-tachyarrhythmia/ TOPLINE:  Adenosine is safe for treating supraventricular tachycardia (SVT) in children in emergency settings, and patients have not experienced sustained ventricular tachycardia or prolonged cardiac pauses requiring intervention. METHODOLOGY: Researchers conducted a retrospective, cross-sectional, multi-hospital study involving 77 patients younger than 18 years (34 girls; median age, 9 years) treated with […]

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Hormone Therapy for Menopause Remains at Historic Lows

Source link : https://www.newshealth.biz/health-news/hormone-therapy-for-menopause-remains-at-historic-lows/ CHICAGO — Less than 4% of American women aged 50-59 years use hormone therapy (HT) to treat menopausal symptoms today, approximately 10 times lower than the peak use of HT before the publication of the 2002 Women’s Health Initiative (WHI) study that misguidedly cast doubt on the safety of HT. Though […]

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EHR Nudges and Primary Care Outcomes

Source link : https://www.newshealth.biz/health-news/ehr-nudges-and-primary-care-outcomes/ TOPLINE: Electronic health record (EHR) nudges were linked to improved documentation and patient-centeredness in primary care. However, their impact on other healthcare quality measures and patient outcomes was less consistent. METHODOLOGY: Researchers performed an electronic search on June 9, 2023, in PubMed, Embase, PsycINFO, CINAHL, and Web of Science for articles […]

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Clinicians Criticize Alberta’s Proposed Sex Ed Policy Change

Source link : https://www.newshealth.biz/health-news/clinicians-criticize-albertas-proposed-sex-ed-policy-change/ For decades, Canadian public health officials, researchers, and clinicians have worked hand in hand with government officials to stem the rise of preventable and treatable sexually transmitted infections (STIs) such as syphilis, gonorrhea, and chlamydia. But Alberta legislators are working to change the rules governing sexual health education even as the […]

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Most Women With GSM Lacked Adequate Treatment

Source link : https://www.newshealth.biz/health-news/most-women-with-gsm-lacked-adequate-treatment/ CHICAGO — The vast majority of women experiencing genitourinary syndrome of menopause (GSM) symptoms did not receive a prescription for hormonal vaginal therapies prior to seeking care at a specialized menopause clinic, according to research presented at the North American Menopause Society (NAMS) 2024 Annual Meeting in Chicago on September 12. […]

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Is Obesity Linked to Pediatric Hidradenitis Suppurativa?

Source link : https://www.newshealth.biz/health-news/is-obesity-linked-to-pediatric-hidradenitis-suppurativa/ TOPLINE: Children with hidradenitis suppurativa (HS) are more likely to have obesity than those without the condition, a review suggests. METHODOLOGY: To evaluate the relationship between HS and obesity in children, an association that has been established in adults, researchers conducted a scoping review of 12 studies, which included one case […]

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Hypofractionated RT Noninferior for Locoregional BC

Source link : https://www.newshealth.biz/health-news/hypofractionated-rt-noninferior-for-locoregional-bc/ BARCELONA, Spain — Hypofractionated radiotherapy is noninferior to conventional fractionation for the locoregional treatment of early breast cancer, suggested new results of a phase 3 trial. Sofia Rivera, MD, PhD, presented these 5-year results of HypoG-01 at the European Society for Medical Oncology (ESMO) Annual Meeting 2024. Rivera, who is an […]

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2024 Pay Raise Not Enough, Many Residents Feel Underpaid

Source link : https://www.newshealth.biz/health-news/2024-pay-raise-not-enough-many-residents-feel-underpaid/ Medical resident salaries and stipends increased for 2024, but the majority of those surveyed say they still feel underpaid, according to Medscape Resident Salary & Debt Report 2024. Over the last 9 years, resident earnings have increased by just a combined 27%, considered slow growth given the rising cost of living. […]

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Radium-223 Plus Enzalutamide Ups Survival in Prostate Cancer

Source link : https://www.newshealth.biz/health-news/radium-223-plus-enzalutamide-ups-survival-in-prostate-cancer/ BARCELONA, Spain — Adding bone-targeting radium-223 (Ra223) to the androgen receptor pathway inhibitor enzalutamide (Xtandi) in patients with metastatic castration-resistant prostate cancer and bone metastases significantly improves survival outcomes, according to the first results from the PEACE III trial. The research, presented at the European Society for Medical Oncology (ESMO) Annual […]

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Flavored Vape Use Cut Cigarette Smoking in High-Risk Adults

Source link : https://www.newshealth.biz/health-news/flavored-vape-use-cut-cigarette-smoking-in-high-risk-adults/ TOPLINE: E-cigarettes in preferred flavors (especially fruity and sweet) combined with very low nicotine content (VLNC) cigarettes reduce smoking behaviors in adults with psychiatric conditions or lower education levels, who are at the greatest risk for smoking-related harm. METHODOLOGY: Researchers hypothesized that cigarettes with VLNC used in combination with vapes that […]

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Antibiotic resistance forecast to kill 39 million people by 2050

Source link : https://www.newshealth.biz/health-news/antibiotic-resistance-forecast-to-kill-39-million-people-by-2050/ Some microbes have a growing resistance to our antibiotics iStockphoto The number of global deaths directly attributable to antibiotic-resistant bacterial infections is forecast to rise from a record 1.27 million a year in 2019 to 1.91 million a year by 2050. In total, antibiotic resistance is expected to kill 39 million […]

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Brain changes during pregnancy revealed in detailed map

Source link : https://www.newshealth.biz/health-news/brain-changes-during-pregnancy-revealed-in-detailed-map/ Daniela Cossio Pregnancy brain really does exist, according to one of the first detailed maps of human-brain changes before, during and after those crucial nine months. Based on 26 scans of one healthy 38-year-old woman’s brain, scientists found “remarkable things” including changes to regions linked to socialising and emotional processing – […]

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Why This ‘Liquid Gold’ Supplement from Cows Is Trending

Source link : https://www.newshealth.biz/health-news/why-this-liquid-gold-supplement-from-cows-is-trending/ Share on PinterestBovine colostrum supplements, which are made from the first milk cows produce after giving birth, are skyrocketing in popularity thanks to claims they provide numerous health benefits. Lakeview Images/Getty Images Bovine colostrum supplements, also known as “liquid gold,” are growing in popularity, in part due to promotion from wellness […]

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Drug-Resistant Bacteria Deaths Projected to Rise 70% by 2050

Source link : https://www.newshealth.biz/health-news/drug-resistant-bacteria-deaths-projected-to-rise-70-by-2050/ Antimicrobial-resistant bacterial infections directly caused more than 1 million deaths worldwide annually from 1990 to 2021, and that number is projected to increase by almost 70% over the next 25 years, according to a systematic analysis. In 2021, 1.14 million deaths that were attributable to bacterial antimicrobial resistance (AMR) occurred across […]

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Severe Sleep Issues May Tell of Later Suicidal Behavior in Preteens

Source link : https://www.newshealth.biz/health-news/severe-sleep-issues-may-tell-of-later-suicidal-behavior-in-preteens/ Sleep disturbance may portend suicidal behavior among preteens, according to a longitudinal cohort study. A study of more than 8,000 kids found that those who reported severe sleep disturbances at age 10 had a higher odds of reporting suicidal ideation or attempt (OR 2.68, 95% CI 1.44-4.98, P=0.002) at age 12, […]

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Microplastics Found in Human Olfactory Bulbs

Source link : https://www.newshealth.biz/health-news/microplastics-found-in-human-olfactory-bulbs/ Microplastics were found in the olfactory bulbs of eight of 15 human brains at autopsy. A total of 16 different synthetic polymer particles and fibers were identified in olfactory bulbs. The olfactory pathway may be a potential entry route for microplastics into the brain. Microplastics were found in the olfactory bulbs […]

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Are Regulators the Root of the Problem of Serious Device Recalls?

Source link : https://www.newshealth.biz/health-news/are-regulators-the-root-of-the-problem-of-serious-device-recalls/ Among cardiovascular devices that were deemed unsafe enough to warrant urgent regulatory action, many had been allowed to skip rigorous premarket clinical testing in the first place, a report showed. Researchers identified 137 Class I recalls affecting 157 unique cardiovascular devices logged by the FDA from 2013 to 2022. Of these […]

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Intimate Partner Violence Tied to Working Memory Decline Into Menopause

Source link : https://www.newshealth.biz/health-news/intimate-partner-violence-tied-to-working-memory-decline-into-menopause/ CHICAGO — Women who had experienced physical intimate partner violence experienced a decline in working memory as they transitioned into menopause, a subgroup analysis of the longitudinal Study of Women’s Health Across the Nation (SWAN) found. Reports of physical intimate partner violence in the year before SWAN baseline — when participants […]

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Type 2 Diabetes Drug Metformin May Also Help People with HIV

Source link : https://www.newshealth.biz/health-news/type-2-diabetes-drug-metformin-may-also-help-people-with-hiv/ Share on PinterestMetformin, a common medication used to treat type 2 diabetes, may also help reduce the viral reservoir in people living with HIV who are undergoing antiretroviral therapy. Francis Dean/Corbis via Getty Images Research indicates that metformin could help reduce the viral reservoir in HIV patients. Metformin is currently used […]

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Medical Cannabinoids in Kids Linked to These Adverse Events

Source link : https://www.newshealth.biz/health-news/medical-cannabinoids-in-kids-linked-to-these-adverse-events/ Cannabinoids used for medical purposes in children and adolescents come with a risk of adverse events, a systematic review and meta-analysis of 23 randomized clinical trials showed. The risk ratio (RR) of developing adverse events was higher in the cannabinoid group than in the control group (1.09, 95% CI 1.02-1.16), Lauren […]

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Win for Perioperative Durvalumab in Muscle-Invasive Bladder Cancer

Source link : https://www.newshealth.biz/health-news/win-for-perioperative-durvalumab-in-muscle-invasive-bladder-cancer/ Adding perioperative durvalumab (Imfinzi) to neoadjuvant chemotherapy significantly improved survival outcomes in cisplatin-eligible patients with muscle-invasive bladder cancer (MIBC), a phase III trial showed. Estimated 24-month event-free survival (EFS) rates reached 67.8% in the durvalumab group and 59.8% in the neoadjuvant chemotherapy-alone group (HR 0.68, 95% CI 0.56-0.82, P Author : […]

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Immediate Test Result Access: The Good, the Bad, and the Complicated

Source link : https://www.newshealth.biz/health-news/immediate-test-result-access-the-good-the-bad-and-the-complicated/ Fred Pelzman is an associate professor of medicine at Weill Cornell, and has been a practicing internist for nearly 30 years. He is medical director of Weill Cornell Internal Medicine Associates. “Dr. Pelzman, can you explain what all those scary little red arrows pointing up mean?” It feels like nearly every […]

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Another Possible Treatment Option for Intermediate-Stage Liver Cancer

Source link : https://www.newshealth.biz/health-news/another-possible-treatment-option-for-intermediate-stage-liver-cancer/ Progression-free survival (PFS) in intermediate-stage hepatocellular carcinoma (HCC) improved by almost 5 months when a targeted agent and immunotherapy were added to transarterial chemoembolization (TACE), initial results from a randomized trial showed. Median PFS increased from 10 months with TACE to 14.6 months with the addition of lenvatinib (Lenvima) and pembrolizumab […]

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GLP-1 Drugs in MASLD Tied to Lower Risk of Cirrhosis, Death

Source link : https://www.newshealth.biz/health-news/glp-1-drugs-in-masld-tied-to-lower-risk-of-cirrhosis-death/ GLP-1 receptor agonist use was associated with a reduced risk of progressing to cirrhosis and related complications in patients with diabetes and metabolic dysfunction-associated steatotic liver disease (MASLD), according to an analysis of Veterans Affairs data. In a matched cohort study of more than 30,000 patients, use of a GLP-1 agonist […]

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High-Intensity Noninvasive Ventilation May Reduce Intubation for COPD Exacerbation

Source link : https://www.newshealth.biz/health-news/high-intensity-noninvasive-ventilation-may-reduce-intubation-for-copd-exacerbation/ High-intensity noninvasive positive pressure ventilation (NPPV) might have reduced need for endotracheal intubation for persistent hypercapnia during acute exacerbation of chronic obstructive pulmonary disease (COPD), the randomized HAPPEN trial from China showed. NPPV adjusted to a tidal volume of 10-15 mL/kg of predicted body weight led to 4.8% of patients meeting […]

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Junior doctors accept 22% pay rise to end strikes

Source link : https://www.newshealth.biz/health-news/junior-doctors-accept-22-pay-rise-to-end-strikes/ Junior doctors in England have voted to accept the government’s offer of a 22% pay rise over two years, ending their long-running dispute. Members of the British Medical Association backed the deal with 66% voting in favour. It brings to an end the 18-month dispute, which saw junior doctors take part […]

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Brain Health Risks: Digital Quality Measures and the Future of Neurological Care

Source link : https://www.newshealth.biz/health-news/brain-health-risks-digital-quality-measures-and-the-future-of-neurological-care/ Moura is a clinical neurologist and a health informatics expert. Ndemo is a clinical informatics manager. Weathers is a neurohospitalist and an associate chief medical information officer. As the American Academy of Neurology’s (AAN) Brain Health Summit convenes in September, it’s an opportune moment to explore the future of neurology and […]

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Scientists Show How Pregnancy Changes the Brain in Innumerable Ways

Source link : https://www.newshealth.biz/health-news/scientists-show-how-pregnancy-changes-the-brain-in-innumerable-ways/ Neuroscientist Liz Chrastil, PhD, got the unique chance to see how her brain changed while she was pregnant and share what she learned in a new study that offers the first detailed map of a woman’s brain throughout gestation. The transition to motherhood, researchers discovered, affects nearly every part of the […]

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The complicated role loneliness plays in 26 common health conditions

Source link : https://www.newshealth.biz/health-news/the-complicated-role-loneliness-plays-in-26-common-health-conditions/ Loneliness is associated with multiple health conditions Marc Bruxelle RF / Alamy The idea that loneliness leads to certain health conditions is now being called into question. Although loneliness is associated with a range of negative physical health outcomes, including an increased risk of premature death, it might just be correlated […]

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Evidence grows for dramatic brain remodelling during pregnancy

Source link : https://www.newshealth.biz/health-news/evidence-grows-for-dramatic-brain-remodelling-during-pregnancy/ Pregnancy may permanently change parts of the brain bernardbodo/iStockphoto/Getty Images The human brain goes through significant changes during pregnancy with few regions untouched, according to the first ever map of this over the course of gestation and beyond. Some regions of the brain shrink during this time, while others grow and […]

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Reproductive Rights Central to Wisconsin Ob/Gyn’s Run for Congress

Source link : https://www.newshealth.biz/health-news/reproductive-rights-central-to-wisconsin-ob-gyns-run-for-congress/ As part of MedPage Today‘s occasional series on healthcare clinicians running for office, Washington Editor Joyce Frieden spoke with ob/gyn Kristin Lyerly, MD, a Democrat who is running for a U.S. House seat in Wisconsin. The winner of the election will fill both the unexpired term of Rep. Mike Gallagher (R), […]

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What Factors Predict Clinically Meaningful Weight Loss With GLP-1 Agonists?

Source link : https://www.newshealth.biz/health-news/what-factors-predict-clinically-meaningful-weight-loss-with-glp-1-agonists/ In this video interview, Hamlet Gasoyan, PhD, staff investigator at the Cleveland Clinic’s Center for Value-Based Care Research, discusses his recent study in JAMA Network Open that looked at the weight outcomes and factors associated with clinically meaningful weight loss at 1 year among patients with obesity receiving the GLP-1 agonists […]

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Chemo-Free Triplet Yields 68% Response Rate in Richter Transformation

Source link : https://www.newshealth.biz/health-news/chemo-free-triplet-yields-68-response-rate-in-richter-transformation/ A three-drug regimen involving a PD-L1 inhibitor and two targeted agents was active and safe for treating the diffuse large B-cell lymphoma (DLBCL) variant of Richter transformation, the phase II MOLTO study found. Among 28 previously untreated patients, the overall response rate reached 67.9% (95% CI 47.6-84.1) following six cycles of […]

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UK to offer vaccines to boost mpox protection

Source link : https://www.newshealth.biz/health-news/uk-to-offer-vaccines-to-boost-mpox-protection/ Getty Images An mpox vaccine will be offered to thousands of men who have sex with men and some healthcare workers in the UK to boost protection against a form of the virus at the centre of an outbreak in parts of Africa, the government has said. It has bought more […]

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