Source link : https://www.newshealth.biz/health-news/remarkable-weight-loss-with-novel-oral-combo-in-phase-1/ MADRID — Amycretin, a dual pathway, oral weight loss drug, led to up to 13% body weight loss in participants with overweight or obesity according to phase 1, first-in-human study data presented at the European Association for the Study of Diabetes (EASD) 2024 annual meeting. Body weight loss was “remarkable for […]
Tag:Health
Source link : https://www.newshealth.biz/health-news/icodec-semaglutide-combo-shows-benefit-in-type-2-diabetes/ MADRID — Novo Nordisk’s investigational once-weekly combination of insulin icodec plus semaglutide (IcoSema) could benefit people with type 2 diabetes who don’t reach target glycemic goals with either single agent alone, new research suggests. Data for three 52-week multicenter randomized open-label trials from the company’s phase 3a COMBINE program were presented […]
Source link : https://www.newshealth.biz/health-news/sports-doc-sex-abuse-probe-corpse-in-hospital-catering-oven-herpes-vax-flop/ Note that some links may require registration or subscription. Indiana University is investigating a sports doctor for alleged sexual abuse inflicted on former men’s basketball players. (IndyStar) Neighborhood suicide rates tracked with poor local health insurance coverage, broadband internet access, and income, according to CDC data. (Morbidity and Mortality Weekly Report) […]
Source link : https://www.newshealth.biz/health-news/belimumab-hits-newer-remission-low-disease-activity-metrics/ TOPLINE: A greater proportion of patients with active systemic lupus erythematosus (SLE) treated with belimumab plus standard therapy achieved the newest definitions for remission and low disease activity compared with those treated with placebo plus standard therapy, with benefits observed as early as week 28 for remission and week 8 for […]
Source link : https://www.newshealth.biz/health-news/why-talk-of-nhs-reforms-may-give-you-a-sense-of-deja-vu/ Getty Images Across more than 150 pages, NHS surgeon and independent peer Lord Darzi sets out in clear, painstaking detail the failings of the NHS in England. But that is the easy bit – fixing it is an altogether different challenge. The government is promising the “biggest reimagining” of the NHS […]
Source link : https://www.newshealth.biz/health-news/gi-targeted-bitter-hop-extract-curbs-hunger-food-cravings/ TOPLINE: A gastrointestinal (GI)-targeted bitter hop extract reduced hunger and food cravings, as well as post-fast ad libitum energy intake, among women undergoing a 24-hour, water-only fast in a small, randomized crossover trial. METHODOLOGY: Researchers conducted a randomized, double-blind, crossover study with 30 normal-weight women ages 18-40 with BMIs of 18.5-25. […]
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What Are the Best Practices?
Source link : https://www.newshealth.biz/health-news/what-are-the-best-practices/ Research offers promising insights into the ideal frontline therapies for mantle cell lymphoma (MCL), but there are continued unmet needs in the relapsed/refractory setting, blood cancer specialists told colleagues. In the frontline setting, findings suggest that regimens should differ significantly on the basis of whether patients are older or younger, whereas […]
Source link : https://www.newshealth.biz/health-news/montana-hospital-to-pay-10-8m-to-settle-cancer-fraud-suit/ As the deadline nears for a Montana healthcare system to pay what has been called a “jaw-dropping” settlement of nearly $11 million dollars to resolve an alleged violation of the False Claims Act, the legal troubles for the oncologist at the center of the case are ongoing and escalating. On August […]
Source link : https://www.newshealth.biz/health-news/tusa-rav-not-better-than-docetaxel-for-nsclc/ SAN DIEGO — The novel antibody-drug conjugate tusamitamab ravtansine (tusa rav, Sanofi) did not demonstrate greater efficacy than docetaxel in treating advanced nonsquamous non–small cell lung cancer (NSCLC), according to the final results of a study. These findings, which were presented at the World Conference on Lung Cancer (WCLC) 2024 on […]
Source link : https://www.newshealth.biz/health-news/is-minimal-access-nipple-sparing-mastectomy-a-safer-option/ TOPLINE: In patients with early breast cancer, the overall complication rates were similar among those who underwent minimal access nipple-sparing mastectomies and those who underwent conventional nipple-sparing mastectomy, but the rates of specific complications varied. Given that both procedures appear safe overall, the choice may be guided by patients’ preference. METHODOLOGY: […]
Source link : https://www.newshealth.biz/health-news/eating-fruits-and-oats-ups-type-1-diabetes-risk-in-kids/ TOPLINE: MADRID — In children with a genetic susceptibility to type 1 diabetes (T1D), a higher consumption of oats, fruits, or rye may increase the risk for T1D and islet autoimmunity by the age of 6 years, while eating berries may reduce the risk. METHODOLOGY: An increase in the incidence of […]
Source link : https://www.newshealth.biz/health-news/early-vs-late-fast-window-is-one-more-effective/ MADRID — A daily 8-hour eating window controls blood glucose whether followed early or late in the day by people at risk for type 2 diabetes, showed a time-restricted eating (TRE) study presented at the European Association for the Study of Diabetes (EASD) 2024 Annual Meeting. The study, examining shifting the […]
Source link : https://www.newshealth.biz/health-news/expert-warns-of-ai-pitfalls-in-dermatology/ HUNTINGTON BEACH, Calif. — When Roxana Daneshjou, MD, PhD, began reviewing responses to an exploratory survey she and her colleagues created on dermatologists’ use of large language models (LLMs) such as ChatGPT in clinical practice, she was both surprised and alarmed. Of the 134 respondents who completed the survey, 87 (65%) […]
Source link : https://www.newshealth.biz/health-news/ai-doubles-cardiomyopathy-detection-in-pregnant-women/ TOPLINE: Artificial intelligence (AI)–guided screening using digital stethoscopes doubled the detection of left ventricular systolic dysfunction (LVSD) in pregnant and postpartum women in Nigeria. Cardiomyopathy during pregnancy and postpartum is challenging to diagnose due to symptom overlap with normal pregnancy changes. AI-guided screening showed a significant improvement in diagnosis rates compared […]
Source link : https://www.newshealth.biz/health-news/no-benefit-to-anticoagulation-after-stemi-revascularization/ LONDON — There appears to be no advantage for continuing anticoagulation treatment after primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI), according to the results of a large randomized controlled trial presented at the European Society of Cardiology (ESC) Congress 2024 on August 31. Updated data from the RIGHT […]
Source link : https://www.newshealth.biz/health-news/fda-investigates-tampons-for-potential-lead-and-metal-risks/ September 11, 2024 — The FDA has launched an investigation of the potential exposure to heavy metals when using tampons, the agency announced Tuesday. The move follows the publication earlier this year of concerning laboratory test results that detected the presence of more than a dozen metals in a variety of […]
Source link : https://www.newshealth.biz/health-news/ultra-processed-doesnt-always-mean-bad-heres-how-to-tell/ September 11, 2024 — You may have been warned that ultra-processed foods can wreak havoc on your health. But not all of them are created equal. A new study out of The Lancet Regional Health — Americas looked at different types of ultra-processed foods and found that some were even linked with […]
Source link : https://www.newshealth.biz/health-news/diabetic-complications-increase-risk-for-periodontitis/ TOPLINE: Diabetic neuropathy and retinopathy are associated with a higher risk for moderate/severe periodontitis. Dyslipidemia further increases this risk, highlighting the need for comprehensive management in patients with diabetes. METHODOLOGY: Researchers conducted a cross-sectional analysis using data from the Health in Central Denmark study, including 15,922 participants with type 2 diabetes. […]
Source link : https://www.newshealth.biz/health-news/hormone-therapy-can-benefit-women-into-their-80s/ Hormone therapy (HT) can help women manage menopause symptoms into their 80s, and the reasons are varied, according to a retrospective analysis being presented at the annual meeting of The Menopause Society. “It’s important to know that this is a preselected group of women who had no contraindications to continuing their […]
Source link : https://www.newshealth.biz/health-news/should-car-t-best-be-used-in-early-mm-relapse/ HOUSTON — Chimeric antigen receptor T-cell therapy (CAR T) has emerged as a game changer for the treatment of multiple myeloma (MM), but questions remain as to how — and when — the immunotherapy will best be used for patients who experience disease relapse. Will CAR T be best used in […]
Source link : https://www.newshealth.biz/health-news/study-reports-safety-data-in-children-on-jak-inhibitors/ TOPLINE: Reports of blood and lymphatic disorders were higher in pediatric patients treated with Janus kinase (JAK) inhibitors than in adults in a review of US and Canadian adverse event (AE) data, which also found that acne was the most common skin-related AE in children, and serious AEs were less common. […]
Source link : https://www.newshealth.biz/health-news/pap-therapy-linked-to-decreased-heart-failure-attacks/ TOPLINE: The utilization of positive airway pressure (PAP) therapy is associated with reduced rates of mortality and incidence of major adverse cardiovascular events (MACEs) in older adults with obstructive sleep apnea (OSA), with a greater utilization further reducing these risks. METHODOLOGY: Researchers conducted a retrospective clinical cohort study including 888,835 older […]
Source link : https://www.newshealth.biz/health-news/early-glaucoma-doesnt-impair-vision-related-quality-of-life/ TOPLINE: Patients with ocular hypertension who develop primary open-angle glaucoma (POAG) without visual field loss did experience a decreased vision-related quality of life compared with those who did not develop the condition. METHODOLOGY: This cross-sectional study included 679 participants (mean age, 73.8 years; 60.7% women) with ocular hypertension from the Ocular […]
Source link : https://www.newshealth.biz/health-news/one-dose-of-a-smallpox-vaccine-still-gives-good-protection-for-mpox/ There is little good-quality research into smallpox vaccines’ effectiveness against mpox Emmanuele Contini/NurPhoto via Getty Images Receiving a single dose of one type of smallpox vaccine seems to lower the risk of catching mpox by around 60 per cent, although this may vary depending on the variant of the virus. Cases […]
Source link : https://www.newshealth.biz/health-news/is-there-a-surgical-shortcut-to-six-pack-abs/ Welcome to Culture Clinic, MedPage Today‘s collaboration with Northwell Health to offer a healthcare professional’s take on the latest viral medical topics. Getting defined six-pack abs is no easy task, but there is a procedure that can give patients a boost in achieving the results they want. High-definition liposuction or liposculpture, […]
Source link : https://www.newshealth.biz/health-news/circulating-h5n1-bird-flu-spotted-by-wastewater-monitoring-during-summer/ H5N1 influenza surfaced in wastewater samples across all 10 Texas cities monitored by the TexWEB team at the Texas Epidemic Public Health Institute in Houston. From March 4 through July 15, the group detected H5N1 in 10 of 10 cities, at 22 of 23 sites, and in 100 of 399 samples, […]
Source link : https://www.newshealth.biz/health-news/threats-to-whistleblowers-rampant-fraud-plague-transplant-system-lawmakers-told/ Presumably deceased organ donors waking up and mouthing, “Help me.” Organ transplant executives threatening whistleblowers with being “cremated alive.” Pancreases that could be used for transplant put in freezers and then getting “lost.” Rampant Medicare and Medicaid fraud. These were examples of problems with the current organ transplant system that House […]
Source link : https://www.newshealth.biz/health-news/cheap-antidepressant-flops-for-severe-breathlessness-in-trial/ An inexpensive antidepressant proved no better than placebo for alleviating severe, persisting breathlessness from chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD), a phase III trial indicated. After 56 days of treatment, “worst breathlessness” over the past 24 hours — the study’s primary outcome — was no different between […]
Source link : https://www.newshealth.biz/health-news/second-malignancy-risk-with-car-t-cell-therapy-on-par-with-other-treatments/ CAR T-cell therapy carried a risk of second primary malignancy (SPM) that was no worse than that of other standard-of-care (SOC) cancer therapies, according to a systematic literature review and meta-analysis. The analysis showed a 5.8% rate of SPM among 5,517 patients with a median follow-up of 21.7 months. The rate […]
Source link : https://www.newshealth.biz/health-news/microvascular-diabetes-complications-linked-to-moderate-severe-gum-disease/ Certain diabetes complications were linked to moderate and severe periodontitis, a cross-sectional analysis using Danish population-based data suggested. Among nearly 16,000 patients with type 2 diabetes, adjusted models showed that diabetic neuropathy (OR 1.36, 95% CI 1.14-1.63) and retinopathy (OR 1.21, 95% CI 1.03-1.43) were significantly associated with moderate/severe periodontitis, reported […]
Source link : https://www.newshealth.biz/health-news/nhs-must-reform-or-die-pm-to-say-after-critical-report/ Getty Images “Ballooning” NHS waiting times and delays getting vital treatment in A&E and cancer care is harming health and costing lives, according to a critical government-commissioned report. People have “every right to be angry,” Sir Keir Starmer will warn on Thursday, adding the health service must “reform or die”. Health […]
Source link : https://www.newshealth.biz/health-news/inpatient-cbt-reduces-suicide-and-readmissions-after-discharge/ Brief cognitive behavioral therapy (BCBT) sessions adapted for psychiatric inpatients reduced postdischarge suicide attempts and readmission rates, according to a randomized clinical trial. In a trial of 200 participants at a private psychiatric hospital, providing up to four sessions of BCBT-inpatient (BCBT-I) treatment reduced the occurrence of suicide attempts by 60% […]
Source link : https://www.newshealth.biz/health-news/fda-reviewers-skeptical-of-ocaliva-for-rare-bile-duct-disease/ FDA advisors on Friday will be asked to find any clinical benefit in the rocky, mostly-null evidence for obeticholic acid (Ocaliva) in primary biliary cholangitis (PBC). In its present supplemental new drug application, sponsor Intercept Pharmaceuticals is proposing an indication for obeticholic acid to reduce hepatic decompensation, liver transplant, and death […]
Source link : https://www.newshealth.biz/health-news/antibody-drug-conjugate-shows-promising-activity-in-extensive-stage-sclc/ Treatment with the antibody drug-conjugate ifinatamab deruxtecan (I-DXd) showed promising activity in pretreated patients with extensive-stage small cell lung cancer (SCLC), particularly those treated at a higher dose, according to an interim analysis of the phase II IDeate-Lung01 study. In the dose optimization part of the study, which evaluated two doses, […]
Source link : https://www.newshealth.biz/health-news/uva-med-defends-top-leaders-after-docs-call-for-ouster/ The University of Virginia is defending the CEO of its health system and its medical school dean in the wake of a very public call for their removal. At least 128 members of the University of Virginia faculty who are employed both by the medical school and the UVA Physicians Group […]
Source link : https://www.newshealth.biz/health-news/james-earl-jones-dies-after-long-battle-with-diabetes-what-to-know/ Share on PinterestHollywood legend James Earl Jones, known for his iconic roles in The Lion King and Star Wars, managed living with type 2 diabetes for over 20 years before his death at 93. Jemal Countess/Getty Images James Earl Jones, known for roles in Field of Dreams, The Lion King, and […]
Source link : https://www.newshealth.biz/health-news/limits-to-anti-nausea-pill-coverage-wear-on-cancer-patients-and-doctors/ Cancer patients can ward off waves of vomiting after treatment with a relatively cheap anti-nausea pill, but some are running into coverage limits. Doctors say restrictions on the number of tablets patients receive can hurt care. Pharmacy benefit managers say their limits guard against overuse, and they offer workarounds to get […]
Source link : https://www.newshealth.biz/health-news/molnupiravir-may-offer-modest-6-month-benefits-for-high-risk-covid-patients/ People with acute COVID-19 who took the antiviral drug molnupiravir (Lagevrio) reported modest improvements in symptoms, less time off from work or study, and less healthcare utilization at 6 months post-infection, a follow-up analysis of the prospective, open-label PANORAMIC trial suggested. Among patients who received molnupiravir 800 mg twice per day […]
Source link : https://www.newshealth.biz/health-news/doc-travels-for-abortion-training-families-wrongly-separated-jail-opioid-success/ Welcome to the latest edition of Investigative Roundup, highlighting some of the best investigative reporting on healthcare each week. Doc Travels for Abortion Training Politico followed an internal medicine and pediatrics resident from an abortion-ban state as she traveled out of state for abortion training. Like other doctors — mostly obstetrics […]
Source link : https://www.newshealth.biz/health-news/never-forget-the-9-11-responders-who-risked-their-lives/ Moline is an occupational medicine physician. Twenty-three years have passed since the attack on the World Trade Center, and like anyone in the New York area, there’s little that has escaped my memory. I was headed back to my Chelsea home the day of the attack, desperately looking for a place […]
Source link : https://www.newshealth.biz/health-news/local-suicide-risk-factors-chappell-roans-bipolar-ii-disorder-student-mindfulness/ Local economic and social conditions like health insurance access, internet, and household income, were tied with suicide risk, according to a new CDC report. The FDA cleared DeepWell Digital Therapeutics’ technology that can be integrated or adjacent to immersive media for the treatment of stress and hypertension. Singer Chappell Roan, who […]
Source link : https://www.newshealth.biz/health-news/ais-drug-revolution-part-3-making-proteins-from-scratch/ This is the third in a three-part series from Medscape on the impact of AI on drug discovery and development. Part 1 is about AI’s role in designing speedier, more effective clinical trials. Part 2 is about the use of AI to find new applications for existing drugs. What if we […]
Source link : https://www.newshealth.biz/health-news/lillys-once-weekly-insulin-shots-effective-new-data-shows/ Share on PinterestEli Lilly’s once-weekly insulin injection is as effective as daily shots for managing blood sugar in diabetes, new data shows. Scott Olson/Getty Images New research offers an alternative to daily insulin shots for the 8 million people in the United States with type 2 diabetes. Eli Lilly’s once-weekly insulin […]
Source link : https://www.newshealth.biz/health-news/liraglutide-reduces-bmi-by-almost-6-in-children-aged-6-to-12/ The glucagon-like peptide-1 (GLP-1) receptor agonist liraglutide is the first in its class to show benefits in young children with obesity, according to results from the phase 3a SCALE-KIDS trial presented at the European Association for the Study of Diabetes (EASD) 2024 Annual Meeting and simultaneously published in the New England […]
Source link : https://www.newshealth.biz/health-news/what-to-know-about-the-investigation-into-floridas-abortion-ballot-initiative/ State police in Florida are showing up at the homes of voters who signed a petition to get an abortion rights amendment on the ballot in November as part of a state probe into alleged petition fraud. Florida Gov. Ron DeSantis (R) has defended police visiting the homes of Floridians who […]
Source link : https://www.newshealth.biz/health-news/states-take-action-against-eastern-equine-encephalitis/ A recent surge in cases of Eastern Equine Encephalitis (EEE) in the northeastern United States, likely brought on by warm weather–induced faster disease spread, has prompted warnings and preventive measures, according to several state public health departments. Recent human cases have set off a wave of mitigation efforts. In August, the […]
Source link : https://www.newshealth.biz/health-news/pesto-linked-to-botulism-cases-in-france/ Getty Images Five people are receiving emergency medical care in France for suspected botulism linked to eating pesto. According to authorities in the Indre-et-Loire department in west-central France, a locally made brand of wild garlic sauce may have been contaminated with a dangerous toxin that can attack the nerves. Cases like […]
Source link : https://www.newshealth.biz/health-news/abortion-covid-and-obamacare-highlighted-in-trump-harris-debate/ Vice President Kamala Harris and former president Donald Trump clashed over the Affordable Care Act (ACA), reproductive rights, and Trump’s response to the COVID-19 pandemic during Tuesday night’s presidential debate in Philadelphia. On Repealing Obamacare At the debate, hosted by ABC News, co-moderator Linsey Davis asked Trump for his plans for […]
Source link : https://www.newshealth.biz/health-news/steroid-use-tied-to-diabetes-suicide-rates-climbing-legionnaires-death-toll-rises/ Note that some links may require registration or subscription. Chronic steroid use more than doubled the risk of type 2 diabetes, a large-scale study showed. (U.S. News & World Report) A novel blood test identified people with accelerated decline in lung function who were at risk of respiratory death, incident chronic […]
Categories
Abdominal Fat Linked to Chronic Pain
Source link : https://www.newshealth.biz/health-news/abdominal-fat-linked-to-chronic-pain/ TOPLINE: MRI-derived abdominal adipose tissue is linked to chronic musculoskeletal pain in multiple sites. The association is stronger in women, suggesting sex differences in fat distribution and hormones. METHODOLOGY: Researchers used data from the UK Biobank, a large population-based cohort study, to investigate the associations between MRI-measured abdominal adipose tissue and […]
Source link : https://www.newshealth.biz/health-news/ifinatamab-deruxtecan-effective-in-es-sclc/ The antibody-drug conjugate ifinatamab deruxtecan (I-DXd) is effective in extensive-stage small cell lung cancer (ES-SCLC), with a higher dose of the drug almost doubling the response rate over a lower dose, suggests the phase 2 Ideate-lung01 study. The research, presented at the IASLC World Conference on Lung Cancer (WCLC) 2024 on […]
Source link : https://www.newshealth.biz/health-news/imaging-technique-reveals-key-features-of-nail-diseases/ TOPLINE: Nailfold capillaroscopy identifies distinct changes in capillary density, length, and morphology in patients with conditions such as nail psoriasis, onychomycosis, and retronychia. METHODOLOGY: The single-center, observational cross-sectional pilot study evaluated patients aged ≥ 7 years with newly diagnosed nail disorders between January 2022 and May 2023. A total of 128 […]
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New Uses for Old Drugs
Source link : https://www.newshealth.biz/health-news/new-uses-for-old-drugs/ This is the second in a three-part series from Medscape Medical News on the impact of artificial intelligence (AI) on drug discovery and development. Part 1 is about AI’s role in designing speedier, more effective clinical trials. Part 3 reports on AI’s ability to create new proteins from scratch, streamlining the […]
Source link : https://www.newshealth.biz/health-news/aumolertinib-promising-maintenance-therapy-in-egfr-nsclc/ SAN DIEGO — Treatment with the estimated glomerular filtration rate (EGFR) tyrosine kinase inhibitor (TKI) aumolertinib after chemoradiation was associated significant improvement in progression-free survival compared with placebo in patients with unresectable stage III EGFR-mutant non–small cell lung cancer (NSCLC). The preplanned interim analysis of the phase 3 POLESTAR study also […]
Source link : https://www.newshealth.biz/health-news/majority-of-hospitalized-patients-with-copd-misuse-inhalers/ Approximately two thirds of hospitalized adults with chronic obstructive pulmonary disease (COPD) received suboptimal treatment with inhalers, mainly resulting from errors, based on data from 96 individuals. “Numerous studies have highlighted the significant issue of improper inhaler use in outpatient settings, but the extent of this problem within hospital settings remains […]
Source link : https://www.newshealth.biz/health-news/beds-and-herts-patients-to-be-re-tested-in-diabetes-results-error/ Getty Images People with diabetes tend to have higher HbA1c levels than those without the condition An NHS trust has revealed that about 11,000 people will have to be re-tested after a hospital machine issued incorrect diabetes results. The Bedfordshire NHS Foundation Trust said some patients may have been wrongly given […]
Source link : https://www.newshealth.biz/health-news/copd-novel-biomarkers-might-improve-monitoring-and-treatment/ VIENNA — Documenting airway thickness in patients with chronic obstructive pulmonary disease (COPD) can help physicians target eosinophilic airway inflammation with biologics, researchers suggest at the European Respiratory Society (ERS) 2024 Congress. Federico Baraldi, PhD Federico Baraldi, PhD, a researcher in respiratory medicine at the University of Ferrara, Ferrara, Italy, and […]
Source link : https://www.newshealth.biz/health-news/once-weekly-insulin-looks-good-in-t2d-but-risk-seen-in-t1d/ MADRID, Spain — Eli Lilly’s investigational once-weekly basal insulin analog efsitora alfa continues to show noninferiority to once-daily insulin in people with type 2 diabetes. However, in those with type 1 diabetes, there was an increased risk for hypoglycemia. The data come from Lilly’s QWINT global phase 3 clinical trial program […]
Source link : https://www.newshealth.biz/health-news/a-simple-blood-test-may-predict-cancer-risk-in-t2d/ TOPLINE: Elevated interleukin (IL) 6 levels are associated with an increased risk for obesity-related cancers in patients newly diagnosed with type 2 diabetes (T2D), potentially enabling the identification of higher-risk individuals through a simple blood test. METHODOLOGY: T2D is associated with an increased risk for obesity-related cancers, including breast, renal, uterine, […]
Source link : https://www.newshealth.biz/health-news/ais-drug-revolution-part-1-faster-trials-and-approvals/ This is the first in a three-part series from Medscape Medical News on the impact of artificial intelligence (AI) on drug discovery and development. Part 2 is about the use of AI to find new applications for existing drugs. Part 3 reports on the AI’s ability to create new proteins from […]
Source link : https://www.newshealth.biz/health-news/long-term-data-support-valve-value-for-emphysema/ VIENNA — Bronchoscopic lung volume reduction (BLVR) was associated with sustained improvements in adults with severe emphysema over a 5-year period, based on data from 190 individuals. The LIBERATE study, a randomized clinical trial, showed the benefits of BLVR for adults with severe emphysema, wrote Gerard J. Criner, MD, and colleagues, […]
Source link : https://www.newshealth.biz/health-news/limited-bariatric-surgery-benefits-in-older-adults/ TOPLINE: For older adults with obesity, bariatric surgery does not appear to significantly reduce the risk for obesity-related cancer and cardiovascular disease (CVD), as it does in younger adults. METHODOLOGY: Bariatric surgery has been shown to decrease the risk for obesity-related cancer and CVD but is typically reserved for patients aged […]
Source link : https://www.newshealth.biz/health-news/should-genetic-testing-be-routine-for-breast-cancer/ TOPLINE: Universal testing identified germline pathogenic variants in 7.3% of women with breast cancer, suggesting that traditional risk-based criteria may miss more than a third of BRCA1, BRCA2, or PALB2 carriers. METHODOLOGY: Traditional risk-based criteria, including family history and ancestry, are used to guide genetic testing decisions in women with breast […]
Source link : https://www.newshealth.biz/health-news/review-provides-look-at-treatments-for-menopause-symptoms/ A more definitive picture of how some hormones and moisturizers can offer relief to women experiencing vaginal dryness or painful intercourse during menopause was published in a recent systematic review in Annals of Internal Medicine. However, researchers noted scant long-term data on the safety of these products. Vaginal dryness and challenges […]
Source link : https://www.newshealth.biz/health-news/eating-the-right-fats-may-help-patients-live-longer/ A diet in which the primary source of fat is plant sources is associated with decreased mortality. Animal fat, on the other hand, is associated with an increased risk for death. These are the results of a study published in JAMA Internal Medicine that followed more than 600,000 participants over two […]
Source link : https://www.newshealth.biz/health-news/prioritizing-treatments-for-mood-disorders-in-perimenopause/ PARIS — Mood disorders are a burdensome symptom that many women have as menopause approaches. Dr Gabriel André, a gynecologist-obstetrician in Strasbourg, France, and Vice-President of GEMVi, provided insights on these disorders at the Santé Paris Femmes 2024 congress. Hormonal Fluctuation For most women, perimenopause, which typically occurs between ages 40 […]
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EFS Depends on Residual Tumor in NSCLC
Source link : https://www.newshealth.biz/health-news/efs-depends-on-residual-tumor-in-nsclc/ SAN DIEGO — The degree of event-free survival (EFS) after surgery in early-stage non–small cell lung cancer (NSCLC) depends on the amount of residual tumor, according to a post hoc analysis of the KEYNOTE-671 study. The authors also found that perioperative pembrolizumab (Keytruda, Merck) continued to show a benefit over placebo […]
Source link : https://www.newshealth.biz/health-news/for-severe-acute-pancreatitis-how-does-chatgpt-measure-up/ TOPLINE: ChatGPT (version 3.5) demonstrates moderate accuracy in responding to guideline-based clinical questions about the management of severe acute pancreatitis. METHODOLOGY: Researchers evaluated the accuracy of ChatGPT in answering 34 short-answer questions and 15 true/false questions regarding the management of severe acute pancreatitis. The artificial intelligence (AI) tool was tested in […]
Source link : https://www.newshealth.biz/health-news/are-pharmacy-deserts-worsening-health-disparities/ TOPLINE: Pharmacy closures in the United States are creating “pharmacy deserts,” disproportionately affecting socially vulnerable communities. High social vulnerability and low primary care practitioner (PCP) density are linked to increased pharmacy desert density. METHODOLOGY: Data through 2020 on communities located 10 or more miles from the nearest retail pharmacy were sourced […]
Source link : https://www.newshealth.biz/health-news/met-inhibitor-increases-osimertinib-activity-in-egfr-advanced-nsclc/ Adding a mutation-specific targeted drug to osimertinib (Tagrisso) substantially increased the objective response rate (ORR) in newly diagnosed EGFR-mutant, MET-aberrant non-small cell lung cancer (NSCLC), a small randomized trial showed. ORR increased from 60.9% with osimertinib alone to 90.5% with the addition of the MET-selective tyrosine kinase inhibitor (TKI) savolitinib. The […]
Source link : https://www.newshealth.biz/health-news/medics-plead-for-vaccines-as-rate-of-infections-increases/ Glody Murhabazi More and more babies with mpox are being admitted to Lwiro community hospital Medical staff on the front line of the battle against mpox in eastern Democratic Republic of Congo have told the BBC they are desperate for vaccines to arrive so they can stem the rate of new […]
Source link : https://www.newshealth.biz/health-news/liraglutide-helped-cut-bmi-in-kids-with-obesity-as-young-as-6/ Liraglutide (Saxenda) added to lifestyle intervention helped reduce BMI in young children with obesity, the phase IIIa SCALE Kids trial found. By week 56, kids, ages 6 to Author : News Health Publish date : 2024-09-10 22:01:00 Copyright for syndicated content belongs to the linked Source.
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Is Football Safe for Kids?
Source link : https://www.newshealth.biz/health-news/is-football-safe-for-kids/ Several young football players died while playing the sport so far this year, raising the perpetual question of whether football is safe for kids. Seven middle and high school students died in August alone while playing the sport — two of them after hits that caused head injuries. Others died from […]
Source link : https://www.newshealth.biz/health-news/go-after-the-big-e-cigarette-makers-not-vape-shops-house-members-tell-fda/ Members of a House committee examining FDA’s regulation of the food and tobacco industries had a question for the agency’s representatives at a hearing Tuesday: Why aren’t you going after big e-cigarette makers? “On the enforcement side, it seems the FDA has chosen to focus on small actors,” Rep. Brett Guthrie […]
Source link : https://www.newshealth.biz/health-news/the-invisible-epidemic-of-childhood-food-insecurity/ Nguyen, Le, Devineni, and Wilson are medical students. Bowers is a pediatric nurse and a medical student. Howell-McLean is an attending physician. It’s Monday at 1 a.m., and a 10-year-old girl comes back from her appendectomy, begging for a snack. After working her way through sips of juice, I grab her […]
Source link : https://www.newshealth.biz/health-news/mammograms-will-include-breast-density-in-reports/ Share on PinterestThe FDA will now require all mammography reports to include whether a person has breast density, which is a breast cancer risk factor. Johnny Greig/Getty Images The FDA will now require all mammography reports to include whether a person has breast density. Breast density is considered a risk factor […]
Source link : https://www.newshealth.biz/health-news/burdensome-therapy-for-severe-hypoxemia-in-copd-patients-is-overkill-trial-says/ The decades-long practice of prescribing long-term oxygen for 24 hours a day to patients with severe hypoxemia from chronic lung diseases appears unnecessary, according to findings from a randomized trial. In patients assigned to 24 hours of oxygen a day, the risk for hospitalization or death was no different at 12 […]
Source link : https://www.newshealth.biz/health-news/woman-claims-weight-loss-drug-led-to-colon-removal/ Share on PinterestA woman is suing the maker of Ozempic, claiming severe side effects from the weight loss drug resulted in the death of a portion of her large intestine. Jens Kalaene/Picture Alliance via Getty Images A woman is suing the maker of Ozempic after she says severe side effects led […]
Source link : https://www.newshealth.biz/health-news/added-plinabulin-boosts-os-as-later-line-treatment-for-egfr-wild-type-nsclc/ Adding the investigational agent plinabulin to docetaxel in the second and third line of treatment significantly improved overall survival (OS) in patients with advanced or metastatic EGFR wild-type non-small cell cancer (NSCLC), the phase III DUBLIN-3 trial showed. Among 559 patients, the median OS was 10.5 months with plinabulin plus docetaxel […]
Source link : https://www.newshealth.biz/health-news/weekly-insulin-efsitora-noninferior-to-daily-degludec-in-type-1-type-2-diabetes/ An investigational once-weekly insulin was noninferior to a daily option for patients with type 2 diabetes, but proved risky for those with type 1 diabetes, the phase III QWINT-2 and -5 trials showed. In insulin-naive patients with type 2 diabetes enrolled in QWINT-2, average HbA1c levels decreased from 8.21% at baseline […]
Source link : https://www.newshealth.biz/health-news/princess-kate-has-completed-chemotherapy-for-cancer/ Following abdominal surgery in 2024, surgeons removed some tissue from Catherine’s abdomen, which was later tested and found to be malignant. “The last nine months have been incredibly tough for us as a family. Life as you know it can change in an instant and we have had to find a […]
Source link : https://www.newshealth.biz/health-news/alzheimers-and-x-chromosomes-identifying-pediatric-mogad-vladimir-lenins-death/ A large-scale X chromosome-wide association study of Alzheimer’s disease identified SLC9A7 as a novel risk locus. (JAMA Neurology) Investigational fosgonimeton did not meet its primary endpoint or key secondary endpoints in mild-to-moderate Alzheimer’s disease in the phase II/III LIFT-AD trial, Athira Pharma said. Research using propofol shed light on the interactions […]
Source link : https://www.newshealth.biz/health-news/defibrillator-positioning-pfa-for-pvc-ablation-harvey-weinsteins-heart-surgery/ Not all defibrillator pad positions may work equally well for patients with shockable out-of-hospital cardiac arrest. (JAMA Network Open) Medical therapy for aortic stenosis? Early clinical data on evogliptin were disappointing but pointed to possible suppression of aortic valve calcification. (Journal of the American College of Cardiology) Osteoporosis treatments alendronic acid […]
Source link : https://www.newshealth.biz/health-news/what-can-we-learn-from-blood-culture-bottle-shortage/ Mehta and Wynia are the co-chairs of the Medical Advisory Panel of the Mountain Plains Regional Disaster Health Response System. On July 10, the FDA issued an advisory to clinicians that Becton Dickinson (BD) had announced a global shortage of their Bactec blood culture bottles — which are essential in the […]
Source link : https://www.newshealth.biz/health-news/fda-advisors-question-potential-role-of-novel-oral-uti-antibiotic/ An FDA advisory committee raised concerns on Monday about the potential for antibiotic resistance with and inappropriate use of a novel oral antibiotic for the treatment of uncomplicated urinary tract infections (uUTIs). During the all-day meeting, members of the Antimicrobial Drugs Advisory Committee reviewed two topics: 1) the overall risks and […]
Source link : https://www.newshealth.biz/health-news/u-k-hospital-where-nurse-was-convicted-of-murdering-7-babies-faces-investigation/ A hospital in northwest England where a neonatal nurse was convicted of murdering seven babies and trying to kill seven others is facing an inquiry into how so many newborns were harmed. The investigation at the Countess of Chester Hospital begins Tuesday against a push by supporters of former nurse Lucy […]
Source link : https://www.newshealth.biz/health-news/finerenone-reduces-t2d-onset-in-hf-with-preserved-ef/ MADRID, Spain — The nonsteroidal mineralocorticoid receptor antagonist (MRA) finerenone reduced the incidence of new-onset type 2 diabetes by approximately 25% in patients with heart failure with mildly reduced or preserved ejection fraction (HFmrEF/HFpEF), according to a prespecified subgroup analysis of the FINEARTS-HF trial. This is “very exciting, and quite a […]
Source link : https://www.newshealth.biz/health-news/questions-linger-about-missouri-patient-who-contracted-bird-flu/ Many questions remain unanswered in the case of the Missouri patient who contracted H5 bird flu without any known exposure to sick or infected animals. “It does raise the concern level, but there is a lot of information needed to understand how much it raises concern,” said Amesh Adalja, MD, of […]
Source link : https://www.newshealth.biz/health-news/the-esmo-congress-starts-this-week-in-barcelona/ More than 30,000 people will descend on Barcelona, Spain, this week for the 2024 European Society for Medical Oncology (ESMO) Congress, which runs from September 13 to 17. Since the meeting’s start in 1975 with about 100 oncologists, it has grown to one of the world’s most important oncology events. This […]
Source link : https://www.newshealth.biz/health-news/human-bird-flu-patient-had-no-known-animal-contact/ A Missouri adult who tested positive for H5 bird flu had no known contact with animals but has underlying medical conditions, according to a statement from the Centers for Disease Control and Prevention (CDC). The case of avian influenza A (H5) was identified as part of Missouri’s normal influenza surveillance testing […]
Source link : https://www.newshealth.biz/health-news/do-sglt2-inhibitors-benefit-everyone-with-t2d-and-ckd/ MADRID, Spain — Nearly half of people with type 2 diabetes (T2D) currently recommended to receive sodium-glucose cotransporter 2 (SGLT2) inhibitors for kidney protection would not actually benefit from them, new research suggests. Current guidelines recommend SGLT2 inhibitors for kidney protection for a broad range of people with T2D, but many […]
Source link : https://www.newshealth.biz/health-news/how-cannabis-laws-and-mental-health-prescription-drugs-are-linked/ In this video interview, Ashley Bradford, PhD, of the Georgia Institute of Technology School of Public Policy in Atlanta, discusses her new paper in JAMA Network Open, which assessed how cannabis laws were associated with prescription fill rates of other mental health medications. The following is a transcript of her remarks: […]
Source link : https://www.newshealth.biz/health-news/contaminated-baby-feed-deaths-inquest-opens/ Getty Images A mother whose premature baby died after receiving contaminated feed at a hospital has told an inquest it was “the worst experience” a parent could have. Ghanda Al-Kharboush’s nine-day-old son, Yousef, died in June 2014 at London’s St Thomas’ Hospital after developing blood poisoning or sepsis. An inquest on […]
Source link : https://www.newshealth.biz/health-news/osimertinib-savolitinib-combo-shows-promise-in-nsclc/ SAN DIEGO — Combination therapy with osimertinib and savolitinib could become a novel first-line treatment option for patients with de novo MET-aberrant, EGFR-mutated advanced non–small cell lung cancer (NSCLC), according to results of the phase 2 FLOWERS study. Compared with EGFR inhibitor osimertinib alone, the combination demonstrated a clinically meaningful improvement […]
Source link : https://www.newshealth.biz/health-news/weinsteins-emergency-condition-georgia-doctor-killed-in-crash-cantaloupe-recalled/ Note that some links may require registration or subscription. Former film producer Harvey Weinstein was rushed to emergency heart surgery from Rikers Island, where he was imprisoned for sex crimes. (ABC News) James Earl Jones, the iconic actor known for voicing Darth Vader, died at age 93. (CNN). Dozens of women […]
Source link : https://www.newshealth.biz/health-news/bilateral-lung-vs-heart-lung-transplant-in-patients-with-pah/ VIENNA — Survival rates at 1 and 5 years for patients with pulmonary arterial hypertension (PAH) who receive bilateral lung and heart-lung transplants are similar, said researchers presenting at the European Respiratory Society (ERS) 2024 International Congress. Transplant for end-stage PAH remains an important treatment option. Heart-lung transplantation plummeted from 91.7% […]
Source link : https://www.newshealth.biz/health-news/asthma-remission-and-egpa-with-biologics/ VIENNA — Physicians are called to record clinical details of patients with asthma undergoing biologic therapy to monitor clinical remission and keep an eye on eosinophilic granulomatosis with polyangiitis (EGPA) symptoms as patients come off the medications, according to pulmonary experts presenting at the European Respiratory Society (ERS) 2024 International Congress. […]
Source link : https://www.newshealth.biz/health-news/can-antihistamines-trigger-seizures-in-young-kids/ TOPLINE: First-generation antihistamines are linked to a 22% higher risk for seizures in children, new research shows. The risk appears to be most pronounced in children aged 6-24 months. METHODOLOGY: Researchers in Korea used a self-controlled case-crossover design to assess the risk for seizures associated with prescriptions of first-generation antihistamines. They […]
Source link : https://www.newshealth.biz/health-news/did-u-s-government-play-a-role-in-remote-tribes-widespread-illness-and-cancer/ OWYHEE, Nev. — The family placed flowers by a pair of weathered cowboy boots, as people quietly gathered for the memorial of the soft-spoken tribal chairman who mentored teens in the boxing ring and teased his grandkids on tractor rides. Left unsaid, and what troubled Marvin Cota’s family deep down, was […]
Source link : https://www.newshealth.biz/health-news/blood-test-may-predict-childhood-asthma-development/ VIENNA — Simply relying on clinical symptoms is insufficient to predict which children with wheezing will develop asthma and respond to treatments. More objective tests like blood eosinophil counts are needed for early diagnosis and to avoid unnecessary medication use in children unlikely to develop asthma. Sejal Saglani, MD, PhD, a […]