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Molecular Stool Testing Could Cut Colonoscopies by 15%-41%

Source link : https://www.newshealth.biz/health-news/molecular-stool-testing-could-cut-colonoscopies-by-15-41/ Noninvasive surveillance with multitarget stool DNA testing or fecal immunochemical testing (FIT) could potentially match colonoscopy for reducing long-term colorectal cancer (CRC) incidence and mortality. It might also reduce colonoscopies by an estimated 15%-41%. The greatest reduction would likely be achieved by annual FIT-based surveillance, especially with FIT FOB-Gold at a […]

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A Single Jog Can Improve Glucose Metabolism in Young Adults

Source link : https://www.newshealth.biz/health-news/a-single-jog-can-improve-glucose-metabolism-in-young-adults/ TOPLINE: In healthy young adults, a single 30-minute bout of outdoor aerobic exercise significantly reduces fasting and 1-hour glucose levels during an oral glucose tolerance test (OGTT) the next day and improves insulin sensitivity. METHODOLOGY: Recent studies have identified 1-hour post-load glucose concentration during an OGTT as a specific and early […]

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Risk Assessment Tool Can Help Predict Fractures in Cancer

Source link : https://www.newshealth.biz/health-news/risk-assessment-tool-can-help-predict-fractures-in-cancer/ TOPLINE: The Fracture Risk Assessment Tool (FRAX), with bone mineral density, predicts the risk for major osteoporotic fractures and hip fractures in patients with cancer, but FRAX without bone mineral density slightly overestimates these risks, a new analysis found. METHODOLOGY: Cancer-specific guidelines recommend using FRAX to assess fracture risk, but its […]

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Wastewater an Early Warning System for Bird Flu Outbreaks

Source link : https://www.newshealth.biz/health-news/wastewater-an-early-warning-system-for-bird-flu-outbreaks/ LOS ANGELES — Researchers found a biomarker for avian flu in Texas wastewater treatment plants more than a month before the first confirmed cases of H5N1 among Texas dairy cattle in 2024, according to new data presented at the Infectious Disease Week (IDWeek) 2024 Annual Meeting. The retrospective finding demonstrates the […]

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7 Days of Antibiotics as Effective as 14 for BSI

Source link : https://www.newshealth.biz/health-news/7-days-of-antibiotics-as-effective-as-14-for-bsi/ LOS ANGELES — A 7-day antibiotic course for treating hospitalized patients’ bloodstream infection (BSI) was just as effective as a 14-day course, according to new data from a seven-country noninferiority trial. The findings from the Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE) trial has implications for healthcare costs and […]

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Single patient records at heart of NHS 10-year plan

Source link : https://www.newshealth.biz/health-news/single-patient-records-at-heart-of-nhs-10-year-plan/ Single patient records will be at the heart of the government’s new strategy for the NHS in England, ministers say. Currently, records are held locally by a patient’s GP and any hospitals they visit. Work is already under way to join up the records and ministers say they will form part […]

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Groups With Highest Unmet PrEP Needs Emerge in Analysis

Source link : https://www.newshealth.biz/health-news/groups-with-highest-unmet-prep-needs-emerge-in-analysis/ LOS ANGELES — Use of preexposure prophylaxis (PrEP) to prevent HIV is increasing overall, but both the rate of increase for starting PrEP and the rate of unmet need differ widely by demographic group, according to new data from a large study. An analysis by Li Tao, MD, MS, PhD, director […]

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ASA Releases New Primary Stroke Prevention Guideline

Source link : https://www.newshealth.biz/health-news/asa-releases-new-primary-stroke-prevention-guideline/ The American Stroke Association (ASA) has issued a new updated guideline for primary stroke prevention. The first update in a decade, the 2024 Guideline for the Primary Prevention of Stroke, replaces the 2014 version and is intended to be a resource for clinicians to help them implement a variety of prevention […]

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More Than 4 Million US Adults Had Glaucoma in 2022

Source link : https://www.newshealth.biz/health-news/more-than-4-million-us-adults-had-glaucoma-in-2022/ TOPLINE: In 2022, an estimated 4.22 million US adults had glaucoma and nearly 1.5 million of them experienced some vision loss as a result, with notable demographic and geographic disparities seen in the burden of the disease. METHODOLOGY: Researchers used data from the National Health and Nutrition Examination Survey (NHANES; 2005-2008), […]

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PCOS Linked to Hypertensive Blood Pressure in Teens

Source link : https://www.newshealth.biz/health-news/pcos-linked-to-hypertensive-blood-pressure-in-teens/ TOPLINE: Adolescent girls with polycystic ovary syndrome (PCOS) have an increased risk for hypertension, according to a new study which underscores the importance of blood pressure surveillance in this population. METHODOLOGY: The retrospective cohort study examined the association between PCOS and hypertension in adolescent girls within a diverse community-based US healthcare […]

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Recognize the Signs and Symptoms of Chronic Cough

Source link : https://www.newshealth.biz/health-news/recognize-the-signs-and-symptoms-of-chronic-cough/ ORLANDO, Fla. — Asthma is the most common cause of chronic cough in children, but it’s important to be aware of other differential diagnoses for those patients who have less common concerns, according to Rajeev Bhatia, MD, division chief of pulmonology at Phoenix Children’s in Phoenix, Arizona. Bhatia reviewed both the […]

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Cardiac Monitoring Is Crucial in Neuromuscular Disorder Care

Source link : https://www.newshealth.biz/health-news/cardiac-monitoring-is-crucial-in-neuromuscular-disorder-care/ SAVANNAH, Georgia — Heart problems are common in the vast majority of neuromuscular disorders, and cardiac monitoring of patients is crucial, even at younger ages, a neurologist told an audience of nerve/muscle specialists. The cardiac conditions can range from asymptomatic to potentially lethal, said Nicholas J. Silvestri, MD, professor of neurology […]

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How Much Does Long COVID Cost Society? New Data Shed Light

Source link : https://www.newshealth.biz/health-news/how-much-does-long-covid-cost-society-new-data-shed-light/ Long COVID, a major public health crisis, is also becoming a significant economic crisis. A new study in Nature reports that the global annual economic impact of long COVID has hit $1 trillion — or about 1% of the global economy. Long COVID is estimated to affect 6%-7% of adults. Those […]

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Lucy Letby may have harmed more babies in her care, new evidence suggests

Source link : https://www.newshealth.biz/health-news/lucy-letby-may-have-harmed-more-babies-in-her-care-new-evidence-suggests/ Cheshire Police New evidence seen by the BBC suggests more babies in Lucy Letby’s care were harmed – and in one case poisoned with insulin. The former nurse was found guilty of murdering seven babies and attempting to murder seven others – including trying to kill two with insulin at the […]

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The Cure to Gun Violence Begins at the Ballot Box, Not the Trauma Bay

Source link : https://www.newshealth.biz/health-news/the-cure-to-gun-violence-begins-at-the-ballot-box-not-the-trauma-bay/ Dark is an emergency medicine physician and professor. Morris is an MPH student. Among the world’s high income countries, the impact of gun violence is uniquely American. Firearms claim more than 48,000 lives per year in our country. They are one of the leading causes of premature death, and have supplanted […]

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‘This Medical Report Will Have Little Effect’: What We Heard This Week

Source link : https://www.newshealth.biz/health-news/this-medical-report-will-have-little-effect-what-we-heard-this-week/ “I have not heard any fair-minded concerns about her health, so I expect that this medical report will have little effect.” — John Sotos, MD, a retired cardiologist who chronicles presidents’ medical histories, commenting on newly released details about Vice President Kamala Harris’ health. “It’s not going to be a reflection […]

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Case Against Perioperative Beta-Blockers Grows Stronger

Source link : https://www.newshealth.biz/health-news/case-against-perioperative-beta-blockers-grows-stronger/ PHILADELPHIA — Any beta-blocker use was associated with a higher risk of postoperative stroke, according to research that also found that these medications may factor into racial disparities in stroke risk to some degree. Based on the records of patients who underwent noncardiac surgeries at two tertiary centers, there was an […]

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RSV Vaccine Tied to Fewer Hospitalizations, ED Visits in Older, High-Risk Adults

Source link : https://www.newshealth.biz/health-news/rsv-vaccine-tied-to-fewer-hospitalizations-ed-visits-in-older-high-risk-adults/ The respiratory syncytial virus (RSV) vaccine (Abrysvo) was linked with fewer hospitalizations and emergency department (ED) visits in older patients during the first season of the vaccine’s rollout, according to a retrospective analysis. From November 2023-April 2024, adjusted RSV vaccine effectiveness against hospitalizations or ED visits was 90% (95% CI 24-99) […]

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Cataract Surgery Linked With Fewer Falls, Traumatic Injuries in Older Patients

Source link : https://www.newshealth.biz/health-news/cataract-surgery-linked-with-fewer-falls-traumatic-injuries-in-older-patients/ CHICAGO — Patients who had cataract surgery had a significantly lower risk of multiple types of traumatic injuries often associated with falls, an analysis of an international database showed. The risk of fall was 11% lower in patients who had surgery versus those who did not, and the risk of hip […]

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Preeclampsia Flagged by Common Lab Values

Source link : https://www.newshealth.biz/health-news/preeclampsia-flagged-by-common-lab-values/ PHILADELPHIA — Existing blood tests may help identify pregnant women at risk of developing preeclampsia, researchers found from a retrospective chart review. Calculated from lab values taken at admission for labor, the fibrinogen-to-albumin ratio (FAR) emerged as an independent marker for severe preeclampsia (OR 18.49, 95% CI 1.70-200.67) in a single-center […]

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Deep Neuromuscular Blockade Helps Keyhole Surgery, but Not Outcomes Per Se

Source link : https://www.newshealth.biz/health-news/deep-neuromuscular-blockade-helps-keyhole-surgery-but-not-outcomes-per-se/ PHILADELPHIA — A deeper neuromuscular block (NMB) facilitated laparoscopic surgery without having an effect on intraoperative safety and postoperative outcomes, according to a multicenter randomized trial. For patients undergoing a complex elective laparoscopic abdominal surgery in European centers, the incidence of adverse events (AEs) did not differ significantly between those randomized […]

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Myasthenia Gravis Patients May Use Less Steroids After Starting Efgartigimod

Source link : https://www.newshealth.biz/health-news/myasthenia-gravis-patients-may-use-less-steroids-after-starting-efgartigimod/ SAVANNAH, Ga. — One year after starting efgartigimod (Vyvgart) treatment, most generalized myasthenia gravis (gMG) patients significantly reduced corticosteroid use, claims data showed. At 1 year, more than half (55%) lowered glucocorticoid usage by at least 5 mg/day on average, said Neelam Goyal, MD, of Stanford Medicine in Palo Alto, California, […]

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Retinal Injections May Increase Risk for Cataract Surgery Complications

Source link : https://www.newshealth.biz/health-news/retinal-injections-may-increase-risk-for-cataract-surgery-complications/ CHICAGO — Retinal injections for eye disease had a significant association with increased complications rates after cataract surgery, according to a large retrospective cohort study. Seven different postoperative complications occurred two to four times more often in patients who had a history of intravitreal drug injections as compared with those who […]

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We spent years covering the case – here’s why experts are still arguing about it

Source link : https://www.newshealth.biz/health-news/we-spent-years-covering-the-case-heres-why-experts-are-still-arguing-about-it/ BBC There are two parallel universes in the Lucy Letby story. One can be witnessed every day in Liverpool at the public inquiry into her case. Here, the matter of Letby’s guilt is settled. The question for the judge is why Letby was able to harm babies for so long. In […]

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Cyclist Chris Hoy announces that his cancer is terminal

Source link : https://www.newshealth.biz/health-news/cyclist-chris-hoy-announces-that-his-cancer-is-terminal/ Getty Images Sir Chris Hoy performed the baton ceremony before the men’s cycling sprint finals at this year’s Paris Olympics Six-time Olympic cycling champion Sir Chris Hoy has announced that his cancer is terminal. In an interview with the Sunday Times, he says doctors have told him he has between two […]

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Weight loss jabs for unemployed not dystopian, says Wes Streeting

Source link : https://www.newshealth.biz/health-news/weight-loss-jabs-for-unemployed-not-dystopian-says-wes-streeting/ Health Secretary Wes Streeting has dismissed suggestions that plans to provide weight loss jabs to unemployed people with obesity are “dystopian.”. The UK government is launching a five-year trial with pharmaceutical giant Lilly to test if the weight-loss drug Mounjaro can help get more people back to work and ease the […]

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The Best and Worst States for Mental Health Care in the U.S.

Source link : https://www.newshealth.biz/health-news/the-best-and-worst-states-for-mental-health-care-in-the-u-s/ Share on PinterestNew research examined several key factors to determine which states rank the highest and lowest for mental health care. Alexander Spatari/Getty Images New research analyzed seven data points to reveal the worst states for mental health care. Texas topped the list as the worst state for mental health care […]

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Shorter Course of Antibiotics Works for Bloodstream Infections

Source link : https://www.newshealth.biz/health-news/shorter-course-of-antibiotics-works-for-bloodstream-infections/ A 7-day course of antibiotics for patients hospitalized with bloodstream infections was just as effective as a 14-day course, according to results of the randomized, open-label BALANCE trial. Among patients with bloodstream infections who received 7 days of antibiotics, 14.5% had died at 90 days, versus 16.1% of those who received […]

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Sustained Disease Control in Adolescent Myasthenia Gravis With FcRn Blocker

Source link : https://www.newshealth.biz/health-news/sustained-disease-control-in-adolescent-myasthenia-gravis-with-fcrn-blocker/ SAVANNAH, Ga. — Investigational nipocalimab plus standard of care achieved sustained reductions in immunoglobulin G (IgG) and appeared to be safe for adolescent patients with generalized myasthenia gravis (gMG), the phase II/III Vibrance-MG study showed. From baseline to week 24 of the active treatment phase, the mean percentage change in total […]

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What’s in Kamala Harris’ Medical History?

Source link : https://www.newshealth.biz/health-news/whats-in-kamala-harris-medical-history/ The 24-hour news cycle is just as important to medicine as it is to politics, finance, or sports. At MedPage Today, new information is posted daily, but keeping up can be a challenge. As an aid for our readers, and for a little amusement, here is a 10-question quiz based on […]

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Standing More May Not Reduce Stroke, Heart Failure Risk

Source link : https://www.newshealth.biz/health-news/standing-more-may-not-reduce-stroke-heart-failure-risk/ Share on PinterestStanding more isn’t enough to offset the negative health effects of a sedentary lifestyle and may raise the risk of circulatory diseases. Kristine Weilert/Stocksy United Sitting and sedentary behavior are linked to a higher risk of many health conditions, including cardiovascular disease. Standing isn’t enough to offset the negative […]

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Novel Monoclonal Antibody Protects Infants Against RSV

Source link : https://www.newshealth.biz/health-news/novel-monoclonal-antibody-protects-infants-against-rsv/ The investigational monoclonal antibody clesrovimab protected against respiratory syncytial virus (RSV) disease and prevented RSV hospitalizations among healthy preterm- and term infants, according to results of a phase IIb/III study. A single dose of clesrovimab reduced the incidence of RSV-associated medically attended lower respiratory infections (MALRI) that had at least one […]

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Rainfall and Mortality; Identifying Risk for Preeclampsia

Source link : https://www.newshealth.biz/health-news/rainfall-and-mortality-identifying-risk-for-preeclampsia/ TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center in El Paso, look at the top medical stories of the week. This week’s topics include […]

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Informed Consent, Inclusion Prioritized in Revised Ethics for Human Trials

Source link : https://www.newshealth.biz/health-news/informed-consent-inclusion-prioritized-in-revised-ethics-for-human-trials/ The World Medical Association (WMA) voted unanimously today to approve revised ethical principles for human participants in medical research. Updates to the WMA “Declaration of Helsinki” (DoH) include: Respecting “individual autonomy” through “[f]ree and informed consent” that is given voluntarily by the person who will participate in the research Replacing the […]

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Women and Children First — Or Not

Source link : https://www.newshealth.biz/health-news/women-and-children-first-or-not/ Rosenbaum is a pediatrician, and a professor emeritus and special lecturer in pediatrics and medicine. Meyer is a professor of pediatrics and medical director for the community and population health division of a large hospital system. We are both pediatricians and parents. We have patients and children of our own, and […]

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Whooping Cough in the U.S. Is at a Decade-High Level

Source link : https://www.newshealth.biz/health-news/whooping-cough-in-the-u-s-is-at-a-decade-high-level/ Whooping cough is at its highest level in a decade for this time of year, U.S. health officials reported Thursday. There have been 18,506 cases of whooping cough reported so far, the CDC said. That’s the most at this point in the year since 2014, when cases topped 21,800. The increase […]

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How will weight-loss drugs change our relationship with food?

Source link : https://www.newshealth.biz/health-news/how-will-weight-loss-drugs-change-our-relationship-with-food/ BBC We are now in the era of weight-loss drugs. Decisions on how these drugs will be used look likely to shape our future health and even what our society might look like. And, as researchers are finding, they are already toppling the belief that obesity is simply a moral failing […]

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Drugmaker Pulls Trodelvy’s Bladder Cancer Approval

Source link : https://www.newshealth.biz/health-news/drugmaker-pulls-trodelvys-bladder-cancer-approval/ Sacituzumab govitecan’s (Trodelvy) accelerated approval in urothelial cancer will be voluntarily withdrawn, Gilead Sciences announced on Friday. The decision was made in consultation with the FDA and does not affect the antibody-drug conjugate’s other indications, the company said. A Trop-2-directed antibody, sacituzumab govitecan was granted accelerated approval for urothelial cancer in […]

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Immunotherapy and Immune-Related Adverse Events

Source link : https://www.newshealth.biz/health-news/immunotherapy-and-immune-related-adverse-events/ While immunotherapy has revolutionized the way in which oncologists treat cancer, its use comes with a variety of side effects that are very different from those seen with other systemic therapies. These treatments are “revving up the immune system,” said Bryan J. Schneider, MD, of the University of Michigan in Ann […]

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Study: OUD Patients More Likely to Stay on Methadone Than Buprenorphine/Naloxone

Source link : https://www.newshealth.biz/health-news/study-oud-patients-more-likely-to-stay-on-methadone-than-buprenorphine-naloxone/ Patients with opioid use disorder (OUD) had a lower risk of discontinuing methadone compared with buprenorphine/naloxone, and with a similar mortality risk, according to a population-based cohort study published in JAMA. In this video interview, researcher Bohdan Nosyk, PhD, of Simon Fraser University in Burnaby, British Columbia, discusses the findings and […]

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Teen Smoking, Other Tobacco Use Dropped to Lowest Level in 25 Years, CDC Reports

Source link : https://www.newshealth.biz/health-news/teen-smoking-other-tobacco-use-dropped-to-lowest-level-in-25-years-cdc-reports/ Teen smoking hit an all-time low in the U.S. this year, part of a big drop in the use of tobacco among youths overall, the CDC reported Thursday. There was a 20% drop in the estimated number of middle and high school students who recently used at least one tobacco product, […]

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‘Virtual ED’ Helps One Health System Avoid Unnecessary Emergency Department Visits

Source link : https://www.newshealth.biz/health-news/virtual-ed-helps-one-health-system-avoid-unnecessary-emergency-department-visits/ WASHINGTON — Use of a “virtual” emergency department (ED) has saved several patients from unnecessary ED trips in its first few weeks of operation, Sidney “Beau” Raymond, MD, said here Thursday at the fall conference of the National Association of ACOs (NAACOS). “When you talk about impact on people who are […]

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Diet and Prostate Cancer; TTFields OK’d for NSCLC; Cancer Studies Retracted

Source link : https://www.newshealth.biz/health-news/diet-and-prostate-cancer-ttfields-okd-for-nsclc-cancer-studies-retracted/ A healthy diet in prostate cancer patients on active surveillance was associated with a reduced risk of progressing to a more advanced disease state. (JAMA Oncology) Some doctors see a potential downside to FDA’s new requirement to notify women about breast density. (NBC News) Jazz Pharmaceuticals announced that adding lurbinectedin (Zepzelca) […]

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Novel Targeted Drug Approved for Stomach Cancers

Source link : https://www.newshealth.biz/health-news/novel-targeted-drug-approved-for-stomach-cancers/ The FDA approved zolbetuximab (Vyloy), a claudin 18.2 (CLDN18.2)-directed cytolytic antibody, in combination with chemotherapy for the first-line treatment of adults with advanced HER2-negative gastric or gastroesophageal junction (GEJ) adenocarcinoma, the agency announced Friday. “While there have been advances in the first-line treatment of locally advanced unresectable and metastatic gastric and […]

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FDA OKs Zolbetuximab for Gastric, Gastroesophageal Cancer

Source link : https://www.newshealth.biz/health-news/fda-oks-zolbetuximab-for-gastric-gastroesophageal-cancer/ The US Food and Drug Administration (FDA) has approved zolbetuximab (Vyloy, Astellas Pharma) in combination with fluoropyrimidine and platinum-containing chemotherapy for the first-line treatment of locally advanced unresectable or metastatic HER2-negative gastric or gastroesophageal junction adenocarcinoma that is claudin 18.2 positive.  FDA also approved the Ventana CLDN18 (43-14A) RxDx Assay, from […]

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Tpoxx No Better Than Placebo for Clade I Mpox

Source link : https://www.newshealth.biz/health-news/tpoxx-no-better-than-placebo-for-clade-i-mpox/ The antiviral drug tecovirimat (Tpoxx) failed to shorten the duration of mpox lesions or lower mortality among children and adults with clade I mpox in the Democratic Republic of the Congo (DRC), according to results from the randomized, placebo-controlled PALM007 trial. Among hospitalized patients with mpox, lesion resolution took a median […]

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FDA OKs Novel Levodopa-Based Regimen for Parkinson’s

Source link : https://www.newshealth.biz/health-news/fda-oks-novel-levodopa-based-regimen-for-parkinsons/ The US Food and Drug Administration (FDA) has approved foscarbidopa and foslevodopa (Vyalev, AbbVie), a solution of carbidopa and levodopa prodrugs for 24-hour continuous subcutaneous infusion, for the treatment of motor fluctuations in adults with advanced Parkinson’s disease (PD).  Due to the progressive nature of PD, “oral medications are eventually no […]

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How Does This Year’s Flu Shot Stack Up?

Source link : https://www.newshealth.biz/health-news/how-does-this-years-flu-shot-stack-up/ Data from the southern hemisphere show that this year’s flu shot was 34.5% effective against hospitalization in high-risk groups during that half of the globe’s winter respiratory season. It’s not possible to say exactly how that will translate to the northern hemisphere’s upcoming flu season, but the figure is in the […]

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Doctors, Not AI, Should Authorize Treatments

Source link : https://www.newshealth.biz/health-news/doctors-not-ai-should-authorize-treatments/ Kanaparthy is a practicing internal medicine physician specializing in clinical informatics. Last month, California passed a bill ensuring that doctors, not artificial intelligence (AI), have the final say on patients’ treatments and services. The bill, SB1120, allows insurance companies to use AI to review doctors’ recommendations for medical procedures only if […]

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New Flu and Updated COVID Vaccines Greenlighted by Europe

Source link : https://www.newshealth.biz/health-news/new-flu-and-updated-covid-vaccines-greenlighted-by-europe/ Europe’s Committee for Medicinal Products for Human Use (CHMP) recommended granting marketing authorization for two vaccines: Fluad (surface antigen, inactivated, adjuvanted) and Flucelvax (surface antigen, inactivated, prepared in cell cultures) for active immunization against influenza. Together, the vaccines can immunize children from 2 years and older, adults, and those with comorbidities […]

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Generic Medicine OKd by Europe for Thrombocytopenia With HCV

Source link : https://www.newshealth.biz/health-news/generic-medicine-okd-by-europe-for-thrombocytopenia-with-hcv/ Europe’s Committee for Medicinal Products for Human Use (CHMP) has recommended granting a marketing authorization for Eltrombopag Viatris (eltrombopag), a generic medicine for the treatment of children and adults with primary immune thrombocytopenia (ITP), thrombocytopenia associated with chronic hepatitis C virus (HCV) infection, and acquired severe aplastic anemia. The application by […]

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EMA Confirms Rejection of Neurodegenerative Disease Drugs

Source link : https://www.newshealth.biz/health-news/ema-confirms-rejection-of-neurodegenerative-disease-drugs/ The European Medicines Agency (EMA) has upheld an earlier recommendation to deny marketing authorization for Masitinib AB Science (masitinib), an oral treatment for amyotrophic lateral sclerosis (ALS).  In a meeting on October 17, the EMA’s Committee for Medicinal Products for Human Use (CHMP) reaffirmed its concerns about the reliability of the […]

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Gene Therapy Details Revealed in Duchenne Trial

Source link : https://www.newshealth.biz/health-news/gene-therapy-details-revealed-in-duchenne-trial/ SAVANNAH, Ga. — Delandistrogene moxeparvovec (Elevidys), a gene therapy approved to treat Duchenne muscular dystrophy, missed its primary endpoint but differences emerged in other functional outcomes, the phase III EMBARK trial showed. The primary outcome was the change from baseline in North Star Ambulatory Assessment (NSAA) scores at 1 year. The […]

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EMA OKs Sublingual Formulation for Opioid Dependence

Source link : https://www.newshealth.biz/health-news/ema-oks-sublingual-formulation-for-opioid-dependence/ The European Medicines Agency has recommended granting marketing authorization for a new hybrid formulation of buprenorphine as a substitution treatment of opioid drug dependence. Buprenorphine Neuraxpharm is available as multiple-strength sublingual films. The Committee for Medicinal Products for Human Use (CHMP) said its recommendation was intended to cover use in adults […]

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EMA Recommends New Diagnostic Tool for TB

Source link : https://www.newshealth.biz/health-news/ema-recommends-new-diagnostic-tool-for-tb/ A new diagnostic tool for detecting Mycobacterium tuberculosis infection should be granted a marketing authorization, the European Medicines Agency (EMA) has said. On October 17, the EMA’s Committee for Medicinal Products for Human Use concluded that the Siiltibcy skin test showed favorable results compared with two other diagnostic products. Manufactured by the […]

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EMA Authorizes Korjuny for Malignant Ascites

Source link : https://www.newshealth.biz/health-news/ema-authorizes-korjuny-for-malignant-ascites/ In its October 2024 meeting, the European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP) gave the green light for Korjuny (catumaxomab, Lindis Biotech GmbH) to be used for the intraperitoneal treatment of malignant ascites in patients not eligible for further systemic anticancer therapy. The active substance of […]

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Ruxolitinib Cream Shows Promise in Treating Lichen Planus

Source link : https://www.newshealth.biz/health-news/ruxolitinib-cream-shows-promise-in-treating-lichen-planus/ AMSTERDAM — Treatment with ruxolitinib cream, 1.5%, achieved rapid and marked reductions in the clinical signs and symptoms of cutaneous lichen planus, including itch and skin pain, both when given twice daily and as needed, according to data from a phase 2 trial. The research, presented at the European Academy of […]

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EHR Prompt Cut Acute Otitis Media Antibiotic Use by Half

Source link : https://www.newshealth.biz/health-news/ehr-prompt-cut-acute-otitis-media-antibiotic-use-by-half/ LOS ANGELES — Embedding a new discharge order set into electronic health records (EHRs) with a preselected 5-day antibiotic course for children aged 2 years or older diagnosed with acute otitis media (AOM) cut antibiotic duration sharply, according to new data presented at the Infectious Disease Week (IDWeek) 2024 Annual Meeting. […]

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Vestibular Migraine: Less Dizziness With Galcanezumab

Source link : https://www.newshealth.biz/health-news/vestibular-migraine-less-dizziness-with-galcanezumab/ TOPLINE: Galcanezumab was associated with significantly less dizziness in patients with vestibular migraine (VM) compared with placebo, suggests new results from the first randomized clinical trial in VM. METHODOLOGY: The INVESTMENT study was a single-site, double-blind, placebo-controlled randomized clinical trial with 40 participants (mean age, 51 years; 75% women) with a […]

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ACOG Updates Breast Cancer Screening Guidelines

Source link : https://www.newshealth.biz/health-news/acog-updates-breast-cancer-screening-guidelines/ The American College of Obstetricians and Gynecologists (ACOG) has updated its breast cancer screening guidelines, recommending that individuals at an average risk for breast cancer initiate mammography screening at age 40. This change reflects evolving evidence that starting earlier screening yields greater net benefits in reducing breast cancer mortality, particularly for […]

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Can Weight Loss Drugs Also Treat Addiction?

Source link : https://www.newshealth.biz/health-news/can-weight-loss-drugs-also-treat-addiction/ A new study provides more evidence that glucagon-like peptide 1 receptor agonists (GLP-1 RAs) used to treat diabetes and obesity could be repurposed for opioid use disorder (OUD) and alcohol use disorder (AUD). Researchers found that patients with OUD or AUD who were taking semaglutide (Ozempic, Novo Nordisk) or similar medications […]

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No Excess MACE Risk for JAKis in Atopic Dermatitis Analysis

Source link : https://www.newshealth.biz/health-news/no-excess-mace-risk-for-jakis-in-atopic-dermatitis-analysis/ AMSTERDAM — Janus kinase inhibitors (JAKis) do not appear to increase the risk for major adverse cardiovascular events (MACE) among people with atopic dermatitis (AD) treated in a real-world setting, suggested the results of a large, US-based, retrospective cohort study. This holds true even in individuals aged 50 years or older, […]

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Clinicians Face Confusion on Lipid Screenings for Children

Source link : https://www.newshealth.biz/health-news/clinicians-face-confusion-on-lipid-screenings-for-children/ Clinicians receive conflicting advice on whether to order blood tests to screen for lipids in children. A new study could add to the confusion. Researchers found that a combination of physical proxy measures such as hypertension and body mass index (BMI) predicted the risk for future cardiovascular events as well as […]

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Numerous Industrial Products Are Found in the Human Body

Source link : https://www.newshealth.biz/health-news/numerous-industrial-products-are-found-in-the-human-body/ Materials that are in contact with food contain chemical substances that can migrate into food products and subsequently into the human body. Several of these substances have been studied, and the health risks that some of them pose have been well documented. One example is the well-known bisphenol A, which the […]

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Cendakimab Shows Promise in Eosinophilic Esophagitis

Source link : https://www.newshealth.biz/health-news/cendakimab-shows-promise-in-eosinophilic-esophagitis/ VIENNA — Cendakimab, a monoclonal antibody targeting interleukin (IL) 13, improved symptoms and reduced esophageal eosinophil counts in adult and adolescent patients with eosinophilic esophagitis (EoE), according to interim results of a pivotal phase 3 trial. Treatment with cendakimab also improved key endoscopic and histologic features, even in patients who had […]

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Maternal HS Tied to Adverse Outcomes in Children and Mothers

Source link : https://www.newshealth.biz/health-news/maternal-hs-tied-to-adverse-outcomes-in-children-and-mothers/ TOPLINE: Hidradenitis suppurativa (HS) in pregnant women is associated with increased risks for adverse pregnancy outcomes, including hypertensive disorders, gestational diabetes, and severe maternal morbidity, as well as higher neonatal risks such as preterm birth and birth defects. METHODOLOGY: Researchers conducted a population-based longitudinal cohort study in Quebec, Canada, from 2006 […]

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The Hidden Cost of Cancer Treatment: Time Toxicity

Source link : https://www.newshealth.biz/health-news/the-hidden-cost-of-cancer-treatment-time-toxicity/ TOPLINE: Older adults with metastatic cancer living in Mexico spend about 1 in 5 days during the initial months of treatment in contact with a healthcare provider, with a higher time burden for those receiving radiotherapy or cytotoxic chemotherapy and for frail individuals. METHODOLOGY: Time toxicity — days spent with healthcare […]

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7 Study Apps Help Med Students Prep for Exams

Source link : https://www.newshealth.biz/health-news/7-study-apps-help-med-students-prep-for-exams/ Struggling to stay on top of endless medical school information? There’s an app for that. With more medical students reinforcing their classroom lectures with virtual learning, students increasingly depend on digital study apps to help them absorb and retain vast amounts of complex medical information needed to pass licensing exams. Medscape […]

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How do drugs like Wegovy and Mounjaro work?

Source link : https://www.newshealth.biz/health-news/how-do-drugs-like-wegovy-and-mounjaro-work/ Getty The government has suggested weight-loss drugs could boost the economy by helping obese people in England get back to work. But NHS experts have warned treatment services are already overstretched trying to deal with unprecedented demand from patients wanting these drugs. How do Wegovy and Mounjaro work and how successful […]

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Breast cancer patients denied life-extending drug in NHS row

Source link : https://www.newshealth.biz/health-news/breast-cancer-patients-denied-life-extending-drug-in-nhs-row/ Jeannie Ambrose Jeannie Ambrose, one of about 1,000 affected patients, says Enhertu should be made available on the NHS More than a thousand patients with advanced breast cancer are being denied a drug that can keep them alive for longer. It is already available in 19 countries in Europe – including […]

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Continuous Parkinson’s Disease Therapy Wins FDA Nod

Source link : https://www.newshealth.biz/health-news/continuous-parkinsons-disease-therapy-wins-fda-nod/ The FDA approved a subcutaneous 24-hour continuous infusion of foscarbidopa and foslevodopa (Vyalev) for advanced Parkinson’s disease, AbbVie announced Thursday. Foscarbidopa and foslevodopa are pro-drugs for carbidopa and levodopa, which are standard-of-care Parkinson’s treatments. The new treatment, formerly know as ABBV-951, is the first subcutaneous 24-hour-a-day infusion of a levodopa-based therapy […]

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Study Offers Clues for Avoiding RMD Flares After COVID Vaccination

Source link : https://www.newshealth.biz/health-news/study-offers-clues-for-avoiding-rmd-flares-after-covid-vaccination/ Predicting which people with inflammatory rheumatic musculoskeletal diseases (I-RMDs) may experience flares after COVID-19 vaccination just got a bit easier, thanks to a new analysis of more than 7,000 European RMD patients. Factors associated with increased flare rates post-vaccination included active disease at the time, female sex, and — most strongly […]

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Air Pollution Risky After Lung Transplant

Source link : https://www.newshealth.biz/health-news/air-pollution-risky-after-lung-transplant/ For lung transplant recipients, exposure to higher air pollution levels was linked to an increased risk of death or graft failure, a retrospective cohort study found. Living in a zip code exposed to elevated ambient fine particulate matter levels was associated with an increased hazard of death or graft failure, with […]

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Hormonal IUDs Linked to Increased Breast Cancer Risk

Source link : https://www.newshealth.biz/health-news/hormonal-iuds-linked-to-increased-breast-cancer-risk/ Women younger than 50 who used a levonorgestrel-releasing intrauterine device (IUD) had a significantly higher risk of breast cancer as compared with women who did not use hormonal contraceptives, a Danish registry study showed. During follow-up of almost 7 years, hormone-releasing IUD use conferred a 40% higher risk of breast cancer. […]

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Pumpkin Safety Tips; Sleep MD Snoozing Tricks; What It’s Like to Date a Resident

Source link : https://www.newshealth.biz/health-news/pumpkin-safety-tips-sleep-md-snoozing-tricks-what-its-like-to-date-a-resident/ The following contains links to social media websites including X, TikTok, Instagram, Facebook, and LinkedIn. It’s pumpkin patch season, which means … potential back injuries? @ladyspinedoc showed her audience how to lift a pumpkin safely during fall festivities. “Parents, please do not be afraid of shopping carts.” In response to a […]

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New Estimates Show Over 4 Million People in the U.S. Have Glaucoma

Source link : https://www.newshealth.biz/health-news/new-estimates-show-over-4-million-people-in-the-u-s-have-glaucoma/ An estimated 4.22 million people in the U.S. had glaucoma and 1.49 million people had vision-affecting glaucoma in 2022, with Black adults approximately twice as likely as white adults to be affected, according to a meta-analysis. The prevalence of glaucoma was 1.62% among people ages 18 and older and 2.56% among […]

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Stroke Survivors Still Prescribed a ‘Concerning’ Amount of Benzos

Source link : https://www.newshealth.biz/health-news/stroke-survivors-still-prescribed-a-concerning-amount-of-benzos/ More vigilance may be needed regarding the amount of benzodiazepines being dispensed to older stroke survivors, though prescription patterns at the national level have improved in recent years. Medicare records showed that within 90 days of discharge following an acute ischemic stroke, 4.9% of patients 65 years or older initiated a […]

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How Unconventional Thinkers Unlock Medical Innovation

Source link : https://www.newshealth.biz/health-news/how-unconventional-thinkers-unlock-medical-innovation/ Murphy is a clinician, researcher, teacher, and inventor. Despite the uphill battle that most inventors must undertake to bring their innovations to market, the global market for medical device technologies was valued at $550 billion in 2021. By 2030, it is projected to reach $850 billion, reflecting a compound annual growth […]

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Medtronic Warns of Battery Problem With Insulin Pumps

Source link : https://www.newshealth.biz/health-news/medtronic-warns-of-battery-problem-with-insulin-pumps/ Medtronic has issued a second alert letter to patients regarding shortened battery life of the MiniMed 600 and 700 series insulin pumps.  The affected products include the MiniMed 630G, 670G, 770G, and 780G, all lots and serial numbers. The problem can arise when a pump is dropped, bumped, or otherwise physically […]

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As Election Nears, Trump Is Still Not Sharing Any Health Details

Source link : https://www.newshealth.biz/health-news/as-election-nears-trump-is-still-not-sharing-any-health-details/ If he wins next month’s election, Donald Trump would be the oldest person in U.S. history to be elected president. Yet the 78-year-old Republican nominee refuses to disclose new details about his physical or mental well-being, breaking decades of precedent. There have been limited snapshots of Trump’s health over the last […]

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FDA OKs Once-Nightly Lumryz for Children With Narcolepsy

Source link : https://www.newshealth.biz/health-news/fda-oks-once-nightly-lumryz-for-children-with-narcolepsy/ The US Food and Drug Administration (FDA) has approved Avadel Pharmaceuticals’ supplemental new drug application for extended-release sodium oxybate (Lumryz) for treatment of cataplexy or excessive daytime sleepiness in children 7 years of age and older with narcolepsy. The FDA first approved the once-nightly formulation of sodium oxybate for treatment of […]

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HIV-Positive Donors Safe for Kidney Transplants

Source link : https://www.newshealth.biz/health-news/hiv-positive-donors-safe-for-kidney-transplants/ Kidney transplant recipients with HIV who receive organs from HIV-positive donors show no worse safety outcomes compared with those receiving organs from donors without HIV, supporting a proposed change to allow such transplants beyond the current restrictions of research-only settings. “These results will have far-reaching effects in many countries that do […]

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Doc Sues Over Spicy Dish; Disciplined for Doctor’s Note; Ob/Gyn Attacked Near Office

Source link : https://www.newshealth.biz/health-news/doc-sues-over-spicy-dish-disciplined-for-doctors-note-ob-gyn-attacked-near-office/ California doctor Harjasleen Walia, MD, sued a Thai restaurant alleging that its “Dragon Balls” appetizer was so spicy it burned her vocal cords, esophagus, and the inside of her right nostril. The case is set to go to jury trial next year. (SiliconValley.com) Connecticut’s medical board has put a resident physician […]

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Europe’s Deep Dive Into Equitable Cancer Care

Source link : https://www.newshealth.biz/health-news/europes-deep-dive-into-equitable-cancer-care/ Romania faces significant challenges in cancer care, with high cancer mortality rates and limited access to comprehensive screening and treatment programs. “We desperately need to improve,” said Delia Nicoară, a public health specialist at The Oncology Institute “Prof. Dr Ion Chiricuta” in Cluj-Napoca, Romania, speaking to Medscape Medical News. Delia Nicoară […]

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Three States Renew Effort to Reduce Access to Abortion Pill Mifepristone

Source link : https://www.newshealth.biz/health-news/three-states-renew-effort-to-reduce-access-to-abortion-pill-mifepristone/ Three states are renewing a legal push to restrict access to the abortion medication mifepristone (Mifeprex), including reinstating requirements it be dispensed in person instead of by mail. The request from Kansas, Idaho, and Missouri filed Friday would bar the drug’s use after 7 weeks of pregnancy instead of 10 and […]

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SBRT or Surgery in Localized Prostate Cancer: Is One Better?

Source link : https://www.newshealth.biz/health-news/sbrt-or-surgery-in-localized-prostate-cancer-is-one-better/ TOPLINE: In patients with localized prostate cancer, stereotactic body radiotherapy (SBRT) was associated with better urinary continence and sexual function, but slightly worse bowel function, compared with radical prostatectomy, according to a phase 3 open-label, randomized trial evaluating quality-of-life outcomes. METHODOLOGY: Compared with prostatectomy, radiotherapy may offer better urinary and sexual […]

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Kids’ Neurodevelopment Appears Unharmed by Maternal COVID Infection

Source link : https://www.newshealth.biz/health-news/kids-neurodevelopment-appears-unharmed-by-maternal-covid-infection/ Exposure to maternal COVID-19 was not associated with abnormal neurodevelopmental screening results through 24 months’ postpartum, according to a cohort study in JAMA Network Open. In this video interview, researcher Eleni Greenwood Jaswa, MD, MSc, of the University of California San Francisco, discusses the study’s findings and implications. The following is […]

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Conversion Practices Tied to Worse Mental Health Outcomes

Source link : https://www.newshealth.biz/health-news/conversion-practices-tied-to-worse-mental-health-outcomes/ TOPLINE:  Conversion practices targeting gender identity or sexual orientation is associated with increased depression, posttraumatic stress disorder (PTSD), and suicidality in LGBTQ+ adults, a new study shows.  METHODOLOGY: Researchers analyzed data from the PRIDE study, a US-based, online, prospective cohort study of 4426 adults (57% cisgender, 43% transgender/gender diverse) who completed […]

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MDMA Is Off the Table, So What’s Next for PTSD?

Source link : https://www.newshealth.biz/health-news/mdma-is-off-the-table-so-whats-next-for-ptsd/ It has been 24 years since a pharmaceutical was last approved for posttraumatic stress disorder (PTSD). The condition is notoriously difficult to treat, with up to 40% patients finding no relief from symptoms through psychotherapy or current medications. Many clinicians, advocates, and patients had pinned their hopes on the psychedelic drug […]

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COVID Greatly Increases Diabetes Risk in Kids and Teens

Source link : https://www.newshealth.biz/health-news/covid-greatly-increases-diabetes-risk-in-kids-and-teens/ As the nation searches for ways to reduce the number of young people diagnosed with type 2 diabetes, a new prevention pathway is emerging: avoiding COVID-19. Teens and adolescents were much more likely to be newly diagnosed with type 2 diabetes within 6 months of having COVID-19, compared to kids of […]

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Mobile Clinics Provide Birth Control in Rural Areas

Source link : https://www.newshealth.biz/health-news/mobile-clinics-provide-birth-control-in-rural-areas/ Twice a month, a 40-foot-long truck transformed into a mobile clinic travels the Rio Grande Valley to provide rural Texans with women’s healthcare, including birth control. The clinic, called the UniMóvil, is part of the Healthy Mujeres program at the University of Texas Rio Grande Valley School of Medicine. The US […]

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Maternal COVID-19 May Not Harm Baby’s Neural Development

Source link : https://www.newshealth.biz/health-news/maternal-covid-19-may-not-harm-babys-neural-development/ TOPLINE: Fetuses exposed in utero to SARS-CoV-2 are not at an increased risk for neurodevelopmental problems in early childhood. METHODOLOGY: This prospective study aimed to assess whether in utero exposure to SARS-CoV-2, which causes COVID-19, is associated with abnormal neurodevelopment among children at ages 12, 18, and 24 months. It included […]

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Genetic Marker Tied to Severe Ulcerative Colitis Identified

Source link : https://www.newshealth.biz/health-news/genetic-marker-tied-to-severe-ulcerative-colitis-identified/ TOPLINE: VIENNA — Individuals with ulcerative colitis (UC) who carry the HLA-DRB1*01:03 allele are at increased risk of having a more severe disease course requiring major surgery, hospitalization, and high-dose systemic corticosteroids within 3 years of diagnosis, according to a Danish study. METHODOLOGY: Reliable biomarkers are lacking to identify patients with […]

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Pediatric Obesity and MASLD: A Risky Combination for T2D

Source link : https://www.newshealth.biz/health-news/pediatric-obesity-and-masld-a-risky-combination-for-t2d/ MASLD in pediatric obesity was linked to an increased risk for youth-onset type 2 diabetes, especially in the presence of intermediate hyperglycemia. Medscape Medical News Source link : https://www.medscape.com/viewarticle/pediatric-obesity-and-masld-risky-combination-t2d-2024a1000izi?src=rss Author : Publish date : 2024-10-17 11:58:57 Copyright for syndicated content belongs to the linked Source. Author : News Health Publish date […]

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The Heavy Physical and Psychological Burden of PMDD

Source link : https://www.newshealth.biz/health-news/the-heavy-physical-and-psychological-burden-of-pmdd/ Premenstrual disorders (PMDs), including premenstrual dysphoric disorder (PMDD), adversely affect the lives of millions of women worldwide. Most girls and women — as many as 80%-90%— will experience some premenstrual discomfort such as irritability, depressed mood, food or alcohol cravings, bloating, body aches, breast pain, constipation, or fatigue. Diagnosable menstrual disorders […]

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Novel Nerve Block Yields Benefits in Bariatric Surgery

Source link : https://www.newshealth.biz/health-news/novel-nerve-block-yields-benefits-in-bariatric-surgery/ Autonomic neural blockade may represent a unique way to manage postoperative visceral pain and associated symptoms following minimally invasive weight loss surgery, according to a new report in JAMA Surgery. The novel technique targets blockade of sympathetic and parasympathetic pathways by injecting local anesthetic into the areolar tissue surrounding selected autonomic […]

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Induction Chemotherapy Boosts Survival in Cervical Cancer

Source link : https://www.newshealth.biz/health-news/induction-chemotherapy-boosts-survival-in-cervical-cancer/ TOPLINE: Induction chemotherapy followed by chemoradiotherapy improves 5-year overall survival rates in advanced cervical cancer from 72% to 80%. The treatment also enhances 5-year progression-free survival rates from 64% to 72%. METHODOLOGY: Researchers conducted a multicenter, randomized phase 3 INTERLACE trial to evaluate whether short-course induction chemotherapy before chemoradiotherapy is more […]

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Treatment Is in Sight for Charcot-Marie-Tooth Disease

Source link : https://www.newshealth.biz/health-news/treatment-is-in-sight-for-charcot-marie-tooth-disease/ SAVANNAH, Georgia — There’s no medical treatment for Charcot-Marie-Tooth (CMT) disease, a debilitating neurologic disorder that’s both progressive and incurable. But now, nerve specialists learned, new potential treatments are moving closer to clinical trials. Genetic-based therapies are currently in preclinical research phases, and an experimental small-molecule drug has reached phase 3 […]

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First-in-Class B-Cell Depleting Agent Promising for MG

Source link : https://www.newshealth.biz/health-news/first-in-class-b-cell-depleting-agent-promising-for-mg/ SAVANNAH, Georgia — Inebilizumab, a first-in-class anti-CD19 B-cell depleting agent, demonstrated both safety and superior efficacy compared with placebo in patients with seropositive generalized myasthenia gravis (gMG), new phase 3 data showed. “Based on these results, we have demonstrated that targeting B cells, including the antibody-secreting cells, is beneficial, and there […]

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UPFs Associated With Relapse Risk in Crohn’s Disease

Source link : https://www.newshealth.biz/health-news/upfs-associated-with-relapse-risk-in-crohns-disease/ VIENNA — A diet high in ultraprocessed foods (UPFs) increases the risk for clinical relapse in patients with Crohn’s disease (CD) who are in remission, results of a new study suggested. Certain subgroups of UPFs, specifically bread, pastries, and starch as well as oil and spreads, exhibited the strongest association with […]

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