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Excess Deaths Highest Among Younger Minorities During COVID Pandemic

Source link : https://www.newshealth.biz/health-news/excess-deaths-highest-among-younger-minorities-during-covid-pandemic/ When it came to excess U.S. deaths during the COVID pandemic, racial and ethnic disparities hit younger populations particularly hard, a cross-sectional study showed. People ages 25 to 64 had the greatest increases in observed-to-expected all-cause mortality ratios, and these were highest among American Indian/Alaska Native (1.45), Hispanic (1.40), and Native […]

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Study Details Perinatal Risks of Blood Cancers Diagnosed in Pregnancy

Source link : https://www.newshealth.biz/health-news/study-details-perinatal-risks-of-blood-cancers-diagnosed-in-pregnancy/ Women diagnosed with hematologic cancers during pregnancy had increased risks for serious maternal morbidity and obstetric complications, according to results of a large observational study from France, though their survival outcomes were reassuring. The adjusted odds of any severe maternal morbidity during hematologic cancer-associated pregnancies was nearly 23 times higher compared […]

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Experts Highlight Alarming Jump in HIV Infections Among Latinos

Source link : https://www.newshealth.biz/health-news/experts-highlight-alarming-jump-in-hiv-infections-among-latinos/ More resources are urgently needed to overcome the growing HIV crisis among Latinos in the U.S., researchers argued. While annual HIV surveillance reports released by the CDC in May showed that the number of estimated new HIV infections per year nationwide fell by 19% from 2010 through 2022, there was a […]

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Stool test could provide a simpler way to diagnose endometriosis

Source link : https://www.newshealth.biz/health-news/stool-test-could-provide-a-simpler-way-to-diagnose-endometriosis/ Endometriosis tissue viewed under a microscope BIOPHOTO ASSOCIATES/SCIENCE PHOTO LIBRARY Low levels of a particular compound in faeces could be a sign of endometriosis – and supplementation of that compound might even help control the condition. Affecting nearly 200 million people worldwide, endometriosis occurs when the tissue lining the uterus grows […]

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Low Zoster Vaccination Rates in Immunocompromised Veterans

Source link : https://www.newshealth.biz/health-news/low-zoster-vaccination-rates-in-immunocompromised-veterans/ TOPLINE: A study has found that less than half of US veterans on chronic immunosuppressive medications, and a much lower percentage of those younger than 50 years, received at least one dose of the recombinant zoster vaccine (RZV) by mid-2023; the low rate of herpes zoster vaccination in this immunocompromised group, especially […]

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France slashed bird flu outbreaks by vaccinating ducks

Source link : https://www.newshealth.biz/health-news/france-slashed-bird-flu-outbreaks-by-vaccinating-ducks/ A duck getting its flu jab at a French farm in November 2023 Shutterstock/Leitenberge​r Photography France would have had hundreds of outbreaks of H5N1 bird flu on poultry farms in the past year had it not vaccinated ducks against the disease for the first time, according to a modelling study. Instead, […]

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Poppy seed brew causes morphine overdose, alerting lawmakers

Source link : https://www.newshealth.biz/health-news/poppy-seed-brew-causes-morphine-overdose-alerting-lawmakers/ It sounds like a joke: poppy seeds infused with opioids. Indeed, it was a plotline on the sitcom Seinfeld. But for some it has been a tragedy. People have died after drinking tea brewed from unwashed poppy seeds. And after eating lemon poppy seed bread or an everything bagel, mothers reportedly […]

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Elamipretide for Barth Syndrome Survives FDA Advisory Vote

Source link : https://www.newshealth.biz/health-news/elamipretide-for-barth-syndrome-survives-fda-advisory-vote/ FDA advisors indicated a possible path forward for elamipretide as a treatment for Barth syndrome despite the lack of definitive evidence. On Thursday, the Cardiovascular and Renal Drugs Advisory Committee voted 10-6 that elamipretide is effective for the ultra-rare cardioskeletal disease caused by TAFAZZIN gene mutations. Elamipretide is proposed as a […]

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Smartphone Data Flag Early Dementia Risk in Older Adults

Source link : https://www.newshealth.biz/health-news/smartphone-data-flag-early-dementia-risk-in-older-adults/ Older adults at risk for dementia can be identified using mobile data obtained during a wayfinding task, a novel real-world study suggested. During a smartphone-assisted scavenger hunt on a university campus, researchers observed that older adults with subjective cognitive decline (SCD) paused more frequently, likely to reorient themselves, than those without […]

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Kate Middleton’s Post-Chemo Debut; CDC Probes Cancer Cluster; 15M Adults Have ADHD

Source link : https://www.newshealth.biz/health-news/kate-middletons-post-chemo-debut-cdc-probes-cancer-cluster-15m-adults-have-adhd/ Note that some links may require registration or subscription. Kate Middleton, the Princess of Wales, made her first public appearance since finishing chemotherapy. (CNN) The Africa Centers for Disease Control and Prevention criticized the U.S. travel advisory to Rwanda, saying the Marburg outbreak there is under control. (AP) Better use of […]

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Metabolic-Bariatric Surgery Reduces Pancreatic Cancer Risk

Source link : https://www.newshealth.biz/health-news/metabolic-bariatric-surgery-reduces-pancreatic-cancer-risk/ Metabolic-bariatric surgery (MBS) appears to lower the risk for pancreatic cancer in people with obesity, with a potentially greater effect in those who also have type 2 diabetes (T2D), new research suggests. In a meta-analysis of more than 3.7 million adults with obesity, those who had undergone MBS had less than […]

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MMR/MSI Testing for CRC Climbs, But Variations Persist

Source link : https://www.newshealth.biz/health-news/mmr-msi-testing-for-crc-climbs-but-variations-persist/ TOPLINE: Testing for mismatch repair (MMR) and microsatellite instability (MSI) among patients with colorectal cancer (CRC) increased from 22.7% in 2012 to 71.5% in 2021, but variations in access remain, with testing rates differing by cancer stage, individual hospital, patient sex, race, and insurance status. METHODOLOGY: In 2017, the National Comprehensive […]

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Benefit of Screening Colonoscopy Underestimated in NordICC

Source link : https://www.newshealth.biz/health-news/benefit-of-screening-colonoscopy-underestimated-in-nordicc/ TOPLINE: Delayed reporting of cancer diagnosis by registries probably led to the weaker-than-expected effects of screening colonoscopy in preventing colorectal cancer (CRC) observed in the NordICC trial, a new analysis found. METHODOLOGY: The NordICC trial randomly assigned 85,179 adults aged 55-64 years in a 1:2 ratio to receive or not receive […]

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New Gynecology Trials: Could Your Patient Benefit?

Source link : https://www.newshealth.biz/health-news/new-gynecology-trials-could-your-patient-benefit/ Several new studies on gynecologic conditions have started in recent months. Perhaps one of your patients would be interested? Human papillomavirus (HPV) 16–positive, PD-L1–positive, persistent-recurrent or metastatic cervical cancer. Adults with this diagnosis who have progressed on standard first-line therapy of pembrolizumab (Keytruda) plus chemotherapy with/without bevacizumab (Avastin) may be eligible […]

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Early Promise for Vaccine in Parkinson’s and MSA

Source link : https://www.newshealth.biz/health-news/early-promise-for-vaccine-in-parkinsons-and-msa/ PHILADELPHIA — The experimental vaccine UB-312 shows early promise in Parkinson’s disease (PD) and multiple system atrophy (MSA), results of a phase 1b study suggest. “UB-312 immunization in participants with multiple system atrophy and Parkinson’s disease has been safe, well-tolerated, and is able to produce antibodies detectable in serum and cerebrospinal […]

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Live Rotavirus Vax Safe for Babies of Biologic-Treated Moms

Source link : https://www.newshealth.biz/health-news/live-rotavirus-vax-safe-for-babies-of-biologic-treated-moms/ More evidence suggests there is little risk in administering the live rotavirus vaccine to the babies of mothers on biologics during pregnancy for inflammatory bowel disease (IBD). No adverse events or impairment of the immune system emerged in babies at 7 days, 1 month, and 9 months postvaccination, in findings from […]

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New Treatment Effective for Male Postpartum Depression

Source link : https://www.newshealth.biz/health-news/new-treatment-effective-for-male-postpartum-depression/ A psychosocial intervention designed to improve depressive symptoms and promote good parenting skills can be an effective way of treating male postpartum depression, according to new research. In a study conducted in Pakistan, about 70% fathers with postpartum depression who received the intervention showed complete remission of their depressive symptoms and […]

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The ‘Enormous’ Promise of Focused Ultrasound Now Coming True

Source link : https://www.newshealth.biz/health-news/the-enormous-promise-of-focused-ultrasound-now-coming-true/ After several years of investigating focused ultrasound as a tool in treating Alzheimer’s, the field took a big leap forward this year. Elisa Konofagou, PhD, a biomedical engineer who runs the Ultrasound and Elasticity Imaging Laboratory at Columbia University in the City of New York, published the results of her team’s […]

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The Lingering Fatigue of COVID-19

Source link : https://www.newshealth.biz/health-news/the-lingering-fatigue-of-covid-19/ TOPLINE: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was linked to an overall 3% increase in self-reported fatigue and a twofold increase in malaise after minimal exertion up to 18 months after infection. Hospitalized patients experienced a 23% increase in fatigue scores. METHODOLOGY: Researchers conducted a cohort study between 2021 […]

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Physician Empathy Mitigates Patients’ Chronic Pain

Source link : https://www.newshealth.biz/health-news/physician-empathy-mitigates-patients-chronic-pain/ Physicians who treat patients are potentially exposed to two opposing psychological processes: A positive feeling related to the experience of helping someone in need and, on the other hand, the adverse experience of seeing someone’s suffering and being frustrated about their inability to help. The ability to share the feelings of […]

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FDA Approves Inavolisib for PIK3CA-Mutated HR+/HER2− MBC

Source link : https://www.newshealth.biz/health-news/fda-approves-inavolisib-for-pik3ca-mutated-hr-her2%E2%88%92-mbc/ The US Food and Drug Administration (FDA) has approved inavolisib (Itovebi, Genentech) in combination with palbociclib and fulvestrant for endocrine-resistant, PIK3CA-mutated, hormone receptor–positive (HR+), human epidermal growth factor receptor 2–negative (HER2−), locally advanced or metastatic breast cancer following recurrence on or after adjuvant endocrine therapy. The FDA also approved the FoundationOne […]

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Will I be diagnosed with Alzheimer’s like my mother?

Source link : https://www.newshealth.biz/health-news/will-i-be-diagnosed-with-alzheimers-like-my-mother/ Sally Magnusson Sally Magnusson has already written a book about how her family coped with her mother’s dementia There can’t be many people who spend years raging and grieving over the decline of a parent from dementia without wondering if it awaits them too. I’m one. My mother died of this […]

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‘My school’s EpiPen saved my life when I collapsed after drinking ginger beer’

Source link : https://www.newshealth.biz/health-news/my-schools-epipen-saved-my-life-when-i-collapsed-after-drinking-ginger-beer/ BBC Elaine Fraser recognised the symptoms of anaphylactic shock thanks to training by the school where she works When teacher Elaine Fraser collapsed at home after drinking a ginger beer, she had no idea she had an allergy. “It escalated unbelievably quickly,” Elaine recalls. “My chest was concave trying to pull […]

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Excess Body Weight Tied to Increased Risk for Second Cancers

Source link : https://www.newshealth.biz/health-news/excess-body-weight-tied-to-increased-risk-for-second-cancers/ TOPLINE: Cancer survivors who had overweight or obesity at the time of their initial cancer diagnosis have a higher risk for a second primary cancer, particularly an obesity-related cancer, a new analysis found. METHODOLOGY: Cancer survivors have an increased risk for another primary cancer. Studies suggest that lifestyle factors, such as […]

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Can Antiseizure Drugs Increase Cardiovascular Risk?

Source link : https://www.newshealth.biz/health-news/can-antiseizure-drugs-increase-cardiovascular-risk/ Enzyme-inducing antiseizure medications (EIASMs) increase the risk for new-onset cardiovascular events among older adults with epilepsy, a new study suggests. In a prospective cohort study of more than 27,000 patients, the odds of a cardiovascular event were on average 2.2 times greater in patients with epilepsy compared with those without epilepsy. […]

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NHS trust put in place do-not-resuscitate rule, Covid inquiry told

Source link : https://www.newshealth.biz/health-news/nhs-trust-put-in-place-do-not-resuscitate-rule-covid-inquiry-told/ Getty Images Intensive-care units came under severe strain during Covid, the inquiry has heard (stock photo) At least one NHS trust put in place a blanket “do-not-resuscitate” order for sick patients in the pandemic, the Covid inquiry has heard. It would mean individuals had been considered ineligible for potentially lifesaving CPR, […]

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Long-Term Cognitive Monitoring Warranted After First Stroke

Source link : https://www.newshealth.biz/health-news/long-term-cognitive-monitoring-warranted-after-first-stroke/ A first stroke in older adults is associated with substantial immediate and accelerated long-term cognitive decline, suggested a new study that underscores the need for continuous cognitive monitoring in this patient population. Results from the study, which included 14 international cohorts of older adults, showed that stroke was associated with a […]

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Officials Scramble to Protect IV Supplies in Wake of Hurricane Disruption

Source link : https://www.newshealth.biz/health-news/officials-scramble-to-protect-iv-supplies-in-wake-of-hurricane-disruption/ Federal officials are working to move critical hospital supplies out of the path of Hurricane Milton, which is threatening another manufacturer of IV fluids even as hospitals nationwide are still reeling from disruptions caused by flooding at a large factory in North Carolina. Medical manufacturer B. Braun Medical said Wednesday it […]

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Folate Levels in Pregnancy and Congenital Heart Disease Risk

Source link : https://www.newshealth.biz/health-news/folate-levels-in-pregnancy-and-congenital-heart-disease-risk/ TOPLINE: Maternal serum folate levels during early to midpregnancy show a U-shaped association with congenital heart disease (CHD) risk in offspring. Both low and high folate levels are linked to an increased risk, with vitamin B12 deficiency and elevated homocysteine levels further exacerbating this risk. METHODOLOGY: Researchers conducted a case-control study […]

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Peer Reviewers Pocket Millions in Industry Payments

Source link : https://www.newshealth.biz/health-news/peer-reviewers-pocket-millions-in-industry-payments/ TOPLINE:  More than half of the US peer reviewers for four major medical journals received industry payments between 2020 and 2022, new research shows. Altogether they received more than $64 million in general, non-research payments, with a median payment per physician of $7614. Research payments — including money paid directly to […]

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Study Evaluates Safety of BPO Products for Acne

Source link : https://www.newshealth.biz/health-news/study-evaluates-safety-of-bpo-products-for-acne/ Among 111 prescription or over-the-counter products for acne that contain benzoyl peroxide (BPO), 38 (34%) contained benzene levels above the US Food and Drug Administration (FDA) limit of 2 ppm, results from an analysis that used gas chromatography-mass spectrometry and other methods showed. The analysis, which was published on October 7, […]

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Is Thyroid Cancer a ‘Good’ Cancer? Experts & Patients Say No

Source link : https://www.newshealth.biz/health-news/is-thyroid-cancer-a-good-cancer-experts-patients-say-no/ Papillary thyroid cancer is widely known as the “good cancer.” This term has been around for years and is used ubiquitously. Some think it’s “appropriate” because the cancer is highly treatable and has good survival rates. Yet, recent research, provider experiences, and patient feedback suggest the term should no longer be […]

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Pulsed Dye Laser an Option for Acne Treatment

Source link : https://www.newshealth.biz/health-news/pulsed-dye-laser-an-option-for-acne-treatment/ CARLSBAD, Calif. — Lasers and energy-based treatments alone or in combination with medical therapy may improve outcomes for patients with moderate to severe acne, according to Arielle Kauvar, MD. Arielle Kauvar, MD At the Controversies and Conversations in Laser and Cosmetic Surgery annual symposium, Kauvar, director of New York Laser & […]

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Positive Phase 3 Results for First-in-Class Parkinson’s Med

Source link : https://www.newshealth.biz/health-news/positive-phase-3-results-for-first-in-class-parkinsons-med/ PHILADELPHIA — Tavapadon, an experimental first-in-class oral selective partial D1/D5 dopamine receptor agonist for Parkinson’s disease (PD), was shown to significantly reduce disease burden in two phase 3 TEMPO trials. In the TEMPO-3 trial, topline findings reported earlier this year showed that patients with PD and motor fluctuations receiving once-daily tavapadon […]

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A New Way to ‘Smuggle’ Drugs Through the Blood-Brain Barrier

Source link : https://www.newshealth.biz/health-news/a-new-way-to-smuggle-drugs-through-the-blood-brain-barrier/ Getting drugs to the brain is difficult. The very thing designed to protect the brain’s environment — the blood-brain barrier (BBB), tightly packed cells that prevent most substances from passing through — is one of the main reasons diseases like Alzheimer’s are so hard to treat. And even if a drug […]

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Fluconazole Resistance in Vulvovaginal Yeasts Increases

Source link : https://www.newshealth.biz/health-news/fluconazole-resistance-in-vulvovaginal-yeasts-increases/ TOPLINE: Fluconazole resistance in yeast isolates from women with recurrent vulvovaginal candidiasis in Leeds, England, increased from 3.5% to 9.6% over 3 years. Non-Candida albicans yeasts also rose from 6.0% to 12.6% during the same period. METHODOLOGY: Researchers conducted a retrospective data search of vaginal cultures from adult women in Leeds, […]

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Police hand file to CPS

Source link : https://www.newshealth.biz/health-news/police-hand-file-to-cps/ Family Handout The families of Cliff Houghton, Dulcie Middleton, Brian Cunningham and Eva Page were among those calling for fresh investigations into their deaths Detectives investigating hundreds of deaths at a hospital have started handing files to the Crown Prosecution Service (CPS). An independent panel previously found 456 patients died after […]

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Time to fix NHS as long waits continue, experts say

Source link : https://www.newshealth.biz/health-news/time-to-fix-nhs-as-long-waits-continue-experts-say/ Getty Images The government has been warned it must come up with a plan to fix the NHS, amid mounting concern about the lack of progress in cutting long waits. Latest figures for England show the backlog in hospital care has risen slightly and targets to cut the longest waits look […]

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Pimavanserin a Better Option for Parkinson’s Psychosis?

Source link : https://www.newshealth.biz/health-news/pimavanserin-a-better-option-for-parkinsons-psychosis/ PHILADELPHIA — Pimavanserin (Nuplazid) is noninferior to quetiapine in patients with Parkinson’s disease (PD) psychosis at 56 days, results from a phase 3 trial showed. In the first prospective comparison of the two antipsychotics in this patient population, pimavanserin yielded significant improvement across all parameters of efficacy without worsening motor symptoms […]

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Enhance Early Pregnancy Loss Management With Mifepristone

Source link : https://www.newshealth.biz/health-news/enhance-early-pregnancy-loss-management-with-mifepristone/ TOPLINE: Mifepristone plus misoprostol reduces the need for subsequent uterine aspiration and emergency department visits in the management of early pregnancy loss. Despite its effectiveness, mifepristone remains underutilized, with 8.6% of patients receiving it in 2022. METHODOLOGY: Researchers conducted a retrospective cohort study using national insurance claims data of US patients […]

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The Best Tools for Early Childhood Developmental Concerns

Source link : https://www.newshealth.biz/health-news/the-best-tools-for-early-childhood-developmental-concerns/ Early recognition of neurodevelopmental concerns and timely access to services have been shown to result in better outcomes for young children. But not all instruments are of equal value, and new research has sought to identify the most useful among them. For their research, published online on September 16, 2024, in […]

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Epidermal Necrolysis Tied to 34% Mortality in French Study

Source link : https://www.newshealth.biz/health-news/epidermal-necrolysis-tied-to-34-mortality-in-french-study/ TOPLINE: Epidermal necrolysis (EN) — which includes Stevens-Johnson syndrome (SJS), toxic EN (TEN), and SJS and TEN overlap — had an incidence of 2.6 cases per million person-years in a French study of adults. METHODOLOGY: Researchers conducted a nationwide cohort study using the French Health System database that included 1221 adult […]

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AI Device Effectively Identifies Skin Lesions in Study

Source link : https://www.newshealth.biz/health-news/ai-device-effectively-identifies-skin-lesions-in-study/ In January, after the DermaSensor became the first artificial intelligence (AI)-enabled device cleared by the US Food and Drug Administration (FDA) to evaluate lesions suggestive of skin cancer, the potential of the device to bridge a gap in access to dermatologists drew significant attention. In a letter published in npj Digital […]

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Pharma giant GSK to pay $2.2 to settle Zantac lawsuits

Source link : https://www.newshealth.biz/health-news/pharma-giant-gsk-to-pay-2-2-to-settle-zantac-lawsuits/ UK pharmaceutical giant GSK says it will pay as much as $2.2bn (£1.68bn) to settle thousands of cases in US courts over claims that a discontinued version of its heartburn drug Zantac caused cancer. The firm announced that it has reached agreements with 10 law firms who represent around 80,000 claimants. […]

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Families criticise redacted surgeon report

Source link : https://www.newshealth.biz/health-news/families-criticise-redacted-surgeon-report/ Justin Tallis/AFP via Getty Images Lawyers representing children who developed long-term pain and injury after operations at Great Ormond Street Hospital have criticised a heavily redacted report carried out for the trust. More than 700 cases linked to the surgeon Yaser Jabbar are being reviewed including some involving leg lengthening and […]

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FDA Reviewers Cast Doubt on Drug Candidate for Barth Syndrome

Source link : https://www.newshealth.biz/health-news/fda-reviewers-cast-doubt-on-drug-candidate-for-barth-syndrome/ Ahead of an FDA advisory committee meeting on Thursday, agency reviewers cast doubt on the efficacy of elamipretide for Barth syndrome, an ultra-rare disease that has no approved treatments. In its new drug application, Stealth BioTherapeutics described elamipretide as a first-in-class mitochondrial protective agent that theoretically improves the function of cardiolipin-deficient […]

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Some Cancers Occur More Frequently in Multiple Sclerosis Patients

Source link : https://www.newshealth.biz/health-news/some-cancers-occur-more-frequently-in-multiple-sclerosis-patients/ People with MS had a 6% increased risk of developing any type of cancer compared with controls. Risks for bladder, brain, and cervical cancer were higher for people with MS. Risks for prostate, breast, and colorectal cancer were lower. Some cancers occurred more frequently in people with multiple sclerosis (MS) than […]

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Emergency Medicine May Join the ERAS Exodus

Source link : https://www.newshealth.biz/health-news/emergency-medicine-may-join-the-eras-exodus/ Emergency medicine is the latest specialty to explore potential independent residency application options outside the Electronic Residency Application Service (ERAS). On October 8, the Council of Residency Directors in Emergency Medicine (CORD) announced that for the 2025-2026 application season and Match cycle, emergency medicine will likely be shifting to the same […]

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Cardiac Surgery-Associated AKI Lower With Extracorporeal Blood Purification

Source link : https://www.newshealth.biz/health-news/cardiac-surgery-associated-aki-lower-with-extracorporeal-blood-purification/ A nonselective extracorporeal blood purification (EBP) device connected to the cardiopulmonary bypass circuit during surgery reduced the risk of cardiac surgery-associated acute kidney injury (CSA-AKI), a randomized trial found. Within 7 days of undergoing nonemergent cardiac surgery, 28.4% of patients in the EBP group experienced CSA-AKI compared with 39.7% in the […]

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Gene Therapy for Rare Brain Disease Effective, but Comes With Blood Cancer Risk

Source link : https://www.newshealth.biz/health-news/gene-therapy-for-rare-brain-disease-effective-but-comes-with-blood-cancer-risk/ While the use of elivaldogene autotemcel (eli-cel; Skysona) gene therapy has demonstrated long-term efficacy in patients with cerebral adrenoleukodystrophy (CALD), that benefit comes with a risk of developing hematologic cancers, according to results from a pair of studies. In one of the reports, seven of 67 boys with CALD who were […]

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To Improve Indigenous Health, Expand Community Health Aide Programs

Source link : https://www.newshealth.biz/health-news/to-improve-indigenous-health-expand-community-health-aide-programs/ Kliewe is a third-year internal medicine resident. “He’s not breathing normally,” the woman said to the camera that was streaming live beside a patient who appeared to be in his mid-20s. “Can you get an oxygen saturation reading on him?” asked the emergency department attending physician who I was sitting with, […]

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Common Dupuytren’s Therapy Falls Short in Trial

Source link : https://www.newshealth.biz/health-news/common-dupuytrens-therapy-falls-short-in-trial/ In a large, head-to-head trial pitting collagenase injections against limited fasciotomy as treatments for Dupuytren’s contracture, the knife won. In the open-label trial, self-reported hand health scores at 1 year favored the surgical procedure, averaging 17.8 among patients randomized to collagenase injections versus 11.9 for the limited-fasciotomy group on the Patient […]

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Crackdowns on Unproven Stem Cell Therapies Worked Abroad

Source link : https://www.newshealth.biz/health-news/crackdowns-on-unproven-stem-cell-therapies-worked-abroad/ Evidence from Australia and Canada indicated that regulation can help to curb the sale of unproven stem cell therapies, researchers found. Direct-to-consumer marketplaces experienced “marked decreases” in the number of companies selling such products following the introduction of regulatory reforms in both countries, reported Leigh Turner, PhD, of the University of […]

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CMS Unveils Sample $2 Generic Drug List for Medicare Part D Enrollees

Source link : https://www.newshealth.biz/health-news/cms-unveils-sample-2-generic-drug-list-for-medicare-part-d-enrollees/ The Centers for Medicare & Medicaid Services (CMS) on Wednesday issued a request for information on a proposed model program that would lower prices to $2 per month for certain generic drugs purchased through Medicare Part D drug plans, but experts expressed concerns about the potential uptake and usefulness of such […]

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New Evidence That Plaque Buildup Shouldn’t Be Ignored

Source link : https://www.newshealth.biz/health-news/new-evidence-that-plaque-buildup-shouldnt-be-ignored/ Subclinical disease detected on imaging predicts death, report investigators who show that plaque burden found on 3D vascular ultrasound and coronary artery calcium on CT were better predictors of death than traditional risk factors. The work not only highlights the importance of early detection, but it also has clinical implications, said […]

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Hot Days and Methamphetamine Are Now a Deadlier Mix

Source link : https://www.newshealth.biz/health-news/hot-days-and-methamphetamine-are-now-a-deadlier-mix/ PHOENIX — On just 1 sweltering day during the hottest June on record in Phoenix, a 38-year-old man collapsed under a freeway bridge and a 41-year-old woman was found slumped outside a business. Both had used methamphetamine before dying from an increasingly dangerous mix of soaring temperatures and stimulants. Meth is […]

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Antipsychotics Compared; Psychiatrist’s Research Misconduct; Teen Suicide Predictor

Source link : https://www.newshealth.biz/health-news/antipsychotics-compared-psychiatrists-research-misconduct-teen-suicide-predictor/ Not all antipsychotics for schizophrenia spectrum disorder were equally effective for relapse prevention in a large comparative effectiveness study, with quetiapine performing the worst. (JAMA Network Open) In a small study of patients with bipolar depression, 39% achieved clinical response following 4 weeks of intravenous ketamine or intranasal esketamine (Spravato) while […]

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Mindfulness Meditation Similar to Antidepressant for Reducing Anxiety Symptoms

Source link : https://www.newshealth.biz/health-news/mindfulness-meditation-similar-to-antidepressant-for-reducing-anxiety-symptoms/ Mindfulness meditation appeared to be similar to escitalopram (Lexapro) in reducing anxiety symptoms at 8 weeks based on several patient- and clinician-reported measures, a secondary analysis of a randomized clinical trial showed. Among 276 adults who underwent mindfulness-based stress reduction (MBSR) or received escitalopram, between-group differences corresponded to small effect sizes […]

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Liberal Blood Transfusions Deliver Brain Function Benefit for the Critically Ill

Source link : https://www.newshealth.biz/health-news/liberal-blood-transfusions-deliver-brain-function-benefit-for-the-critically-ill/ A liberal blood transfusion strategy was associated with better neurological outcomes in patients with acute brain injury, a multicenter phase III randomized trial showed. In the TRAIN trial of critically ill people with traumatic brain injury, aneurysmal subarachnoid hemorrhage, or intracerebral hemorrhage, unfavorable neurological function at 180 days was less likely […]

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One Way to Spot Early Cognitive Decline? Medicare Wellness Visits

Source link : https://www.newshealth.biz/health-news/one-way-to-spot-early-cognitive-decline-medicare-wellness-visits/ Medicare annual wellness visits were associated with a 21% increase in mild cognitive impairment diagnoses. Those with a wellness evaluation received a diagnosis 76 days earlier than others. Findings suggest the Medicare wellness visit policy may help identify cognitive impairment earlier. A Medicare annual wellness visit (AWV) was associated with greater […]

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The Flu Vaccine Might Be Less Effective This Year

Source link : https://www.newshealth.biz/health-news/the-flu-vaccine-might-be-less-effective-this-year/ Oct. 4, 2024 — The CDC says the influenza vaccine being used this flu season might be less effective than the one used last flu season, based on reports of how well the vaccine is working in five South American countries. The seasonal flu vaccine cut the risk of hospitalization for […]

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Risk of a Second Primary Melanoma Similar Regardless of Race/Ethnicity

Source link : https://www.newshealth.biz/health-news/risk-of-a-second-primary-melanoma-similar-regardless-of-race-ethnicity/ A melanoma diagnosis increases risk of a second primary melanoma regardless of race or ethnicity, a review of a government database showed. Although white patients had the highest absolute risk for primary melanoma, Black patients had the highest relative risk of second primary melanomas, with a standardized incidence ratio (SIR) of […]

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How Long Should Kids Stay Out of School After They’ve Had COVID?

Source link : https://www.newshealth.biz/health-news/how-long-should-kids-stay-out-of-school-after-theyve-had-covid/ When the daughter of MedPage Today‘s editor-in-chief Jeremy Faust, MD, got COVID in September, he strategized how best to prevent spread of the virus while causing the least disruption to her school schedule. He debated whether the CDC’s most recent isolation guidelines — which recommend resuming activities when symptoms are resolving […]

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How Did Public Health Become a Public Enemy at the Supreme Court?

Source link : https://www.newshealth.biz/health-news/how-did-public-health-become-a-public-enemy-at-the-supreme-court/ In this Instagram Live clip, MedPage Today editor-in-chief Jeremy Faust, MD, and Lawrence Gostin, JD, director of the O’Neill Institute at Georgetown University in Washington, discuss how the Supreme Court has limited the powers of public health and what that could mean for the next pandemic. The following is a transcript […]

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Florida Hospitals in Hurricane Milton’s Path Prepare for the Worst

Source link : https://www.newshealth.biz/health-news/florida-hospitals-in-hurricane-miltons-path-prepare-for-the-worst/ Hospitals and other healthcare facilities on Florida’s Gulf Coast — still reeling from Hurricane Helene — are now revving up for Hurricane Milton. The storm, which is shaping up to be one of the most powerful to hit the region in years, is projected to make landfall a bit south of […]

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Pediatric Naloxone Use Out of Hospital Confirmed Safe

Source link : https://www.newshealth.biz/health-news/pediatric-naloxone-use-out-of-hospital-confirmed-safe/ ORLANDO, Fla. — More than half of youth improved after receiving a dose of naloxone by emergency medical services (EMS) after an emergency dispatch call, according to research presented on September 29 at the American Academy of Pediatrics (AAP) 2024 National Conference. Christopher E. Gaw, MD, MPH, MBE “Emergency responders or […]

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‘The Office’ Star Has Cancer; Trump Sent COVID Tests to Putin? 3% of Teens Are Trans

Source link : https://www.newshealth.biz/health-news/the-office-star-has-cancer-trump-sent-covid-tests-to-putin-3-of-teens-are-trans/ Note that some links may require registration or subscription. Actress Jenna Fischer, who starred in “The Office” TV series, discusses her breast cancer diagnosis and treatment. (People) The Nobel Prize in chemistry was awarded to David Baker, Demis Hassabis, and John Jumper for their work on computational protein design. (AP) The […]

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A Hard Look at Toxic Workplace Culture in Medicine

Source link : https://www.newshealth.biz/health-news/a-hard-look-at-toxic-workplace-culture-in-medicine/ While Kellie Lease Stecher, MD, was working as an OB/GYN in Minneapolis, a patient confided in her a sexual assault allegation about one of Stecher’s male colleagues. Stecher shared the allegation with her supervisor, who told Stecher not to file a report and chose not to address the issue with the […]

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Air Pollution Exposure and Risk for PD, Dyskinesia: New Data

Source link : https://www.newshealth.biz/health-news/air-pollution-exposure-and-risk-for-pd-dyskinesia-new-data/ TOPLINE: Increased exposure to nitrogen dioxide (NO2) and particulate matter with a diameter of ≤ 2.5 µm (PM2.5) is associated with an increased risk for Parkinson’s disease (PD) and dyskinesia, a new study showed. Increased exposure to PM2.5 is also linked to a higher risk for akinetic rigid PD. METHODOLOGY: Researchers […]

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An Unexpected Ally Against Long COVID?

Source link : https://www.newshealth.biz/health-news/an-unexpected-ally-against-long-covid/ TOPLINE: Metformin use in adults with type 2 diabetes (T2D) is associated with a slightly lower incidence of long COVID and death within 180 days after SARS-CoV-2 infection. METHODOLOGY: Previous studies have shown that metformin use before and during SARS-CoV-2 infection reduces severe COVID-19 and postacute sequelae of SARS-CoV-2 (PASC), also […]

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Five hospitals linked to disgraced Great Ormond Street surgeon

Source link : https://www.newshealth.biz/health-news/five-hospitals-linked-to-disgraced-great-ormond-street-surgeon/ Getty Images Great Ormond Street Hospital is one of the world’s leading children’s hospitals An investigation into disgraced bone surgeon Mr Yaser Jabbar has been widened to cover five London hospitals, as 721 patients’ care is being reviewed. His work at St John and St Elizabeth Hospital and Cromwell Hospital, both […]

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Can Wearable Devices Support Recovery After NSCLC Surgery?

Source link : https://www.newshealth.biz/health-news/can-wearable-devices-support-recovery-after-nsclc-surgery/ TOPLINE: A recent analysis, evaluating an intervention in which patients with non–small cell lung cancer (NSCLC) used a wearable device to help monitor exercise post-surgery, found that participants reported an increase in daily steps and vigorous activities as well as less dyspnea and pain compared with those receiving usual care after […]

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Higher Mortality Trend Among CF Patients With CVD

Source link : https://www.newshealth.biz/health-news/higher-mortality-trend-among-cf-patients-with-cvd/ BOSTON — With the remarkable advances made in therapy over the past decade, many patients with cystic fibrosis (CF) can expect to survive into their 50s and even well beyond. But as patients with CF live longer, they are increasingly likely to develop complications such as cardiovascular diseases (CVDs) that beset […]

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Review Highlights GI Risks for Biologic Rxs for Psoriasis

Source link : https://www.newshealth.biz/health-news/review-highlights-gi-risks-for-biologic-rxs-for-psoriasis/ TOPLINE: A review of 10 articles finds that nearly 9% of adverse event (AE) reports with biologics used to treat psoriasis were gastrointestinal (GI)-related and suggests that the relative rate may be higher with interleukin (IL)-17 inhibitors than with other biologics. METHODOLOGY: Researchers conducted a systematic review of pharmacovigilance studies on […]

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Long-Term Antibiotic Use Linked to Increased Risk for RA

Source link : https://www.newshealth.biz/health-news/long-term-antibiotic-use-linked-to-increased-risk-for-ra/ TOPLINE: Long-term antibiotic usage is associated with an increased risk for rheumatoid arthritis (RA). METHODOLOGY: Researchers conducted a population-based retrospective cohort study using data from the National Health Insurance Service–National Health Screening Cohort of Korea database to examine the association between antibiotic usage and the risk for RA. A total of […]

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Late Dupilumab Responders Have Unique Molecular Profile

Source link : https://www.newshealth.biz/health-news/late-dupilumab-responders-have-unique-molecular-profile/ AMSTERDAM — A proteomics study designed to determine why some patients with atopic dermatitis (AD) respond quickly to dupilumab, others respond more slowly, and the remainder do not respond at all demonstrated that molecular responses in these three groups are very different. A discovery that could lead to personalizing therapies, the […]

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Hospitalized COPD Patients With GERD Have Better Outcomes

Source link : https://www.newshealth.biz/health-news/hospitalized-copd-patients-with-gerd-have-better-outcomes/ BOSTON — Gastroesophageal reflux disease (GERD) is associated with better in-hospital outcomes for patients hospitalized with chronic obstructive pulmonary disease (COPD). The finding is a surprise, considering that GERD has been associated with more COPD exacerbations. GERD is also more common among patients with COPD than in the general population. “It […]

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Isa-KRd Induction Shows High MRD Responses

Source link : https://www.newshealth.biz/health-news/isa-krd-induction-shows-high-mrd-responses/ RIO DE JANEIRO — A quadruplet induction regimen of isatuximab, carfilzomib, lenalidomide, and dexamethasone (Isa-KRd) in the treatment of newly diagnosed multiple myeloma (MM) shows a notably high response, with a favorable safety profile, according to the first findings of the ongoing, novel MIDAS trial. “We found that this induction induced […]

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Methotrexate in Atopic Dermatitis: Experts Clarify Dosage

Source link : https://www.newshealth.biz/health-news/methotrexate-in-atopic-dermatitis-experts-clarify-dosage/ Methotrexate (MTX) is a commonly used treatment option for managing refractory atopic dermatitis, especially as an alternative to cyclosporine, anti-interleukins, or anti-JAK treatments. According to the 2022 European EuroGuiDerm guideline, this immunomodulator is “moderately effective, relatively safe, and well-tolerated” for severe atopic dermatitis both in adults and children. However, due to […]

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Can Science Trust Peer Review? Lawsuit Targets Publishers

Source link : https://www.newshealth.biz/health-news/can-science-trust-peer-review-lawsuit-targets-publishers/ The peer-review process, which is used by scientific journals to validate legitimate research, is now under legal scrutiny. The US District Court for the Southern District of New York will soon rule on whether scientific publishers have compromised this system for profit. In mid-September, University of California, Los Angeles neuroscientist Lucina […]

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Lyme disease left me bed-bound

Source link : https://www.newshealth.biz/health-news/lyme-disease-left-me-bed-bound/ Comedian Miranda Hart has revealed her struggle with chronic fatigue after being diagnosed with Lyme disease. In her new book, I Haven’t Been Entirely Honest With You, Hart provides a frank account of the past 10 years, including the challenges posed by ill health. The star’s autobiography also offers a rare […]

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‘Our son died. Now we can use his sperm to have a grandchild’

Source link : https://www.newshealth.biz/health-news/our-son-died-now-we-can-use-his-sperm-to-have-a-grandchild/ Getty Images The couple say they approached the court because they wanted to carry on their son’s “legacy” A couple in India have said they are “delighted” after a court ordered a hospital to hand over the frozen semen sample of their dead son to them so they could have a […]

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Baby-loss certificates offered to more bereaved parents

Source link : https://www.newshealth.biz/health-news/baby-loss-certificates-offered-to-more-bereaved-parents/ Getty Images More bereaved parents in England will now be able to apply for a certificate to formally recognise the loss of their baby. The government has removed a cut-off date that had meant only those who had had a pregnancy loss or miscarriage since September 2018 were eligible. And so […]

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How the Brain Clears Waste; Masked Benzodiazepine Taper; New Hope for PML

Source link : https://www.newshealth.biz/health-news/how-the-brain-clears-waste-masked-benzodiazepine-taper-new-hope-for-pml/ Imaging in neurosurgery patients showed how the brain’s glymphatic system clears waste. (PNAS) Investigational apitegromab met its primary endpoint of motor function improvement in a phase III trial of spinal muscular atrophy, Scholar Rock announced. Masked tapering with a targeted behavioral intervention helped older adults with insomnia discontinue benzodiazepine receptor agonists, […]

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Prime Locations for AEDs; Fluctuating Lp(a); Formalized Telestroke Training?

Source link : https://www.newshealth.biz/health-news/prime-locations-for-aeds-fluctuating-lpa-formalized-telestroke-training/ A study in Taiwan suggested that public automated external defibrillators (AEDs) are optimally located near bus stops and convenience stores. (Journal of the American Heart Association) Many people experienced clinically significant fluctuations in levels of lipoprotein(a), or Lp(a) that put them in different risk categories, according to an analysis of U.K. […]

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Certain Arm Positions Can Lead to Inaccurate Blood Pressure Readings

Source link : https://www.newshealth.biz/health-news/certain-arm-positions-can-lead-to-inaccurate-blood-pressure-readings/ Certain arm positions — supported on a lap or hanging by the side of the body — led to significant overestimation of blood pressure readings compared with standardized positioning, a randomized trial in JAMA Internal Medicine showed, raising concerns about misdiagnosis or overestimation of hypertension. In this video interview, researcher Tammy […]

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Dozens Who Were Told They Failed the Pathology Board Exam Actually Passed

Source link : https://www.newshealth.biz/health-news/dozens-who-were-told-they-failed-the-pathology-board-exam-actually-passed/ Dozens of pathologists who were told they failed their specialty’s board exam over the past 2 years have been alerted that they actually passed. On October 3, the American Board of Pathology (ABPath) released a statement explaining that after a recent reassessment and rescoring of the primary and subspecialty certification exams, […]

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Allergists Mostly Optimistic About Prescribing Biologics for Food Allergy

Source link : https://www.newshealth.biz/health-news/allergists-mostly-optimistic-about-prescribing-biologics-for-food-allergy/ While many allergists were enthusiastic about the potential advantages of biologics compared with existing therapies to treat food allergies, others were worried about their novelty and cost, according to a qualitative study. During interviews with 60 community and academic allergists, four main themes emerged about the use of biologics for food […]

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Selective Role for Single-Agent Ipilimumab After Anti-PD-1 Failure in Melanoma

Source link : https://www.newshealth.biz/health-news/selective-role-for-single-agent-ipilimumab-after-anti-pd-1-failure-in-melanoma/ Patients with wild-type metastatic melanoma that progressed on frontline PD-1 inhibition had almost a 2-year median overall survival (OS) when treated with single-agent ipilimumab (Yervoy), a small retrospective case review showed. Median OS with post-progression ipilimumab was 23.2 months in patients with no targetable biologic markers versus 5.3 months and 4.5 […]

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Checkpoint Inhibitors for Lung Cancer Linked to Pulmonary Embolism

Source link : https://www.newshealth.biz/health-news/checkpoint-inhibitors-for-lung-cancer-linked-to-pulmonary-embolism/ BOSTON — Patients with metastatic lung cancer who were treated with immune checkpoint inhibitors (ICIs) had higher odds of developing a pulmonary embolism, according to a retrospective cohort study. Among propensity-matched cohorts, 17% of patients with metastatic lung cancer who received ICIs developed a pulmonary embolism within 1 year of beginning […]

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This Exercise May Help Lower Back Pain, No Special Equipment Needed

Source link : https://www.newshealth.biz/health-news/this-exercise-may-help-lower-back-pain-no-special-equipment-needed/ Adults younger than age 45 with chronic, nonspecific lower back pain saw significant pain relief with a structured run-walk program in a randomized trial. At the end of 12 weeks, participants in the program scored their pain level an average 15.3 points lower (95% CI 5.3-25.3), on a 100-point scale, than […]

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Here’s This Year’s Crop of Best Children’s Hospitals

Source link : https://www.newshealth.biz/health-news/heres-this-years-crop-of-best-childrens-hospitals/ This year’s “Best Children’s Hospitals” rankings from U.S. News & World Report included some familiar names at the top of the list. Among these were a trio of top hospitals also on last year’s highest performing list: Cincinnati Children’s Hospital Medical Center, Boston Children’s Hospital, and Texas Children’s Hospital, which previously […]

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The Real ‘Danger’ Is Reclassifying Abortion Pills as Controlled Substances

Source link : https://www.newshealth.biz/health-news/the-real-danger-is-reclassifying-abortion-pills-as-controlled-substances/ Sukhavasi is an ob/gyn based in Louisiana. The importance of resilience in medicine is something that has been emphasized to medical students, residents, and attending physicians over the past several years. It is the ability to bounce back after a tough day at work, just so you can do it all […]

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The Project 2025 Promise: Worse Health and Climate Chaos

Source link : https://www.newshealth.biz/health-news/the-project-2025-promise-worse-health-and-climate-chaos/ Zigmund is an associate professor of clinical radiology. Climate change increasingly threatens health and financial well-being. Nearly 8 million acres in the U.S. have burned so far in 2024 in another season of historic fires; many Northeasterners and Midwesterners reel from yet another season of disastrous floods; and not a month […]

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States Sue TikTok, Claiming It’s Addictive and Harms the Mental Health of Children

Source link : https://www.newshealth.biz/health-news/states-sue-tiktok-claiming-its-addictive-and-harms-the-mental-health-of-children/ More than a dozen states and the District of Columbia have filed lawsuits against TikTok on Tuesday, alleging the popular short-form video app is harming youth mental health by designing its platform to be addictive to kids. The lawsuits stem from a national investigation into TikTok, which was launched in March […]

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Nobel Prize in Medicine Awarded to MicroRNA Researchers

Source link : https://www.newshealth.biz/health-news/nobel-prize-in-medicine-awarded-to-microrna-researchers/ This year, the Royal Swedish Academy of Sciences is honoring two US researchers with the Nobel Prize in Medicine for the discovery of a fundamental principle of how gene activity is regulated. Victor Ambros, PhD, a researcher at the University of Massachusetts Chan Medical School in Worcester, Massachusetts, and Gary Ruvkun, […]

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Tirzepatide Shortage Resolved; Compounder Sues FDA; Menopause Mistaken as Dementia

Source link : https://www.newshealth.biz/health-news/tirzepatide-shortage-resolved-compounder-sues-fda-menopause-mistaken-as-dementia/ All doses of the diabetes and weight management injectable tirzepatide (Mounjaro, Zepbound) were taken off the FDA’s shortage list. (Reuters) This prompted a compounding group to sue the FDA for removing the drug from said list. (Reuters) Meanwhile, the agency clarified its policies on the legal restrictions for making copies of […]

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Fla. Hospitals Evacuate; Man Charged in Indian Doctor’s Death; Life Expectancy Limit

Source link : https://www.newshealth.biz/health-news/fla-hospitals-evacuate-man-charged-in-indian-doctors-death-life-expectancy-limit/ Note that some links may require registration or subscription. Hospitals in Florida have begun plans to evacuate in preparation for Hurricane Milton, the second major hurricane in two weeks. (Fierce Healthcare) Today, Vice President Kamala Harris will announce her plan for a Medicare home care benefit. (The Hill) The FDA authorized […]

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Supreme Court Declines Biden’s Appeal in Texas Emergency Abortion Case

Source link : https://www.newshealth.biz/health-news/supreme-court-declines-bidens-appeal-in-texas-emergency-abortion-case/ A court order that says hospitals cannot federally be required to provide pregnancy terminations when they violate a Texas abortion ban will stay for now, the Supreme Court said Monday. The decision is another setback for opponents of Texas’ abortion ban, which for 2 years has withstood multiple legal challenges, including […]

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Hearing Loss Tied to Cognitive Decline

Source link : https://www.newshealth.biz/health-news/hearing-loss-tied-to-cognitive-decline/ Mild or disabling hearing loss in middle-aged and older adults is associated with cognitive impairment, new findings show. However, unlike in previous studies, investigators found no cognitive benefit from wearing hearings aids, except in people with depression.  “Altogether, the present findings combined with prior evidence support that patients with hearing loss […]

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