Source link : https://www.newshealth.biz/health-news/cilta-cel-improves-os-in-r-r-mm/ RIO DE JANEIRO — A single infusion of the chimeric antigen receptor (CAR) T-cell therapy ciltacabtagene autoleucel, or cilta-cel (CARVYKTI, Janssen Biotech, Inc.), reduces the risk for death by 45% vs standard-of-care (SoC) therapies in patients with lenalidomide-refractory multiple myeloma, according to the latest data from the phase 3 CARTITUDE-4 study. […]
Source link : https://www.newshealth.biz/health-news/monitoring-may-reduce-nerve-injury-risk-in-thyroidectomy/ Thyroidectomy patients with larger lesions requiring neck dissection or who require postoperative drain use or suffer from postoperative hypocalcemia are more likely to experience recurrent laryngeal nerve injury than thyroidectomy patients without these risk factors, data from a new study suggest. The results of the study — presented at the American […]
Source link : https://www.newshealth.biz/health-news/higher-daily-buprenorphine-doses-help-manage-oud/ Higher daily buprenorphine doses may help patients better manage opioid use disorder (OUD), data from a National Institutes of Health (NIH) study suggested. The new data highlight that the dose size currently recommended by the US Food and Drug Administration (FDA) and insurance caps on doses are outdated and harmful in […]
Source link : https://www.newshealth.biz/health-news/knowledge-gaps-on-antibiotic-risks-fuel-patient-expectations/ TOPLINE: Variables, such as insurance type, clinic type, and education level were predictors of whether patients reporting that antibiotics would help common conditions such as sore throat. METHODOLOGY: Researchers conducted a survey with 564 adults in six public primary care clinics and two private emergency departments in Texas over an 18-month […]
Source link : https://www.newshealth.biz/health-news/first-newborns-join-screening-for-more-than-200-rare-diseases/ BBC Dominika’s one-day-old daughter Emilia is part of the screening programme The entire genetic code of up to 100,000 newborn babies in England will be analysed by the NHS, with the aim of speeding up the diagnosis and treatment of more than 200 rare diseases. At present, newborns are given a […]
Source link : https://www.newshealth.biz/health-news/social-media-trend-promotes-nitrous-oxide-misuse/ Welcome to Culture Clinic, MedPage Today’s collaboration with Northwell Health to offer a healthcare professional’s take on the latest viral medical topics. An emerging social media trend has a new generation using an old drug — nitrous oxide — with a new name: Galaxy Gas. The trend of inhaling nitrous oxide […]
Source link : https://www.newshealth.biz/health-news/surprise-the-copay-for-prep-just-disappeared/ Carl Schmid and his colleagues got more than they bargained for — in a good way — when they requested that Medicare cover long-acting physician-administered HIV pre-exposure prophylaxis (PrEP) drugs under its Part B program. Oral PrEP drugs had been paid for under Medicare’s Part D drug program, but Part D […]
Source link : https://www.newshealth.biz/health-news/significant-milestone-for-radionuclide-therapy-in-refractory-meningioma/ Use of an approved radionuclide therapy for difficult-to-treat meningioma was associated with substantially improved progression-free survival (PFS) compared with a historical benchmark, according to results of a small single-arm phase II trial. Among 20 patients with surgery- and radiation-refractory intracranial tumors, treatment with lutetium (Lu)-177 dotatate (Lutathera) was associated with a […]
Source link : https://www.newshealth.biz/health-news/metabolic-accelerator-shows-promise-for-weight-loss-side-of-obesity-hfpef-equation/ The novel investigational weight loss agent HU6 had mixed results specifically targeting obesity-related heart failure with preserved ejection fraction (HFpEF), based on the small HuMain-HFpEF trial. After 19 weeks on daily oral HU6 treatment, people shed on average 2.9 kg (~6.3 lb) or 2.7% of their starting body weight relative to […]
Source link : https://www.newshealth.biz/health-news/chemoradiation-plus-immunotherapy-fails-to-improve-survival-in-limited-stage-sclc/ Adding immunotherapy to chemoradiation therapy (CRT) for limited-stage small cell lung cancer (SCLC) failed to improve survival in a randomized trial. As compared with CRT alone, concurrent atezolizumab (Tecentriq) did not improve overall survival (OS), progression-free survival (PFS), distant metastasis-free survival (DMFS), or time to local failure (TTLF). Interestingly, patients who […]
Source link : https://www.newshealth.biz/health-news/some-epilepsy-drugs-tied-to-cardiovascular-events-in-older-people/ An association between epilepsy and cardiovascular events (CVEs) in older people was likely largely due to the use of enzyme-inducing antiseizure medications (EIASM), according to a prospective cohort study from Canada. Among over 27,000 participants, new-onset CVEs were more likely in those with epilepsy than those without (adjusted OR 2.20, 95% […]
Source link : https://www.newshealth.biz/health-news/can-hpv-self-tests-truly-replace-pap-smears/ Back in May of this year, the FDA approved a new method of human papillomavirus (HPV) testing in a healthcare setting. Rather than a standard Pap smear performed with a speculum — a test dreaded by many patients — the new test allows for patients to swab their own vagina using […]
Source link : https://www.newshealth.biz/health-news/hurricanes-like-helene-keep-killing-for-years-to-come/ Hurricanes in the U.S. end up hundreds of times deadlier than the government calculates, contributing to more American deaths than car accidents or all the nation’s wars, a new study said. The average storm hitting the U.S. contributes to the early deaths of 7,000 to 11,000 people over a 15-year period, […]
Source link : https://www.newshealth.biz/health-news/judge-rules-against-stem-cell-clinic/ A federal court has once again ruled against a stem cell clinic, siding with the FDA that fat-derived stem cell treatments are a “drug” and should be regulated as such. The 9th Circuit Court of Appeals determined that stromal vascular fraction (SVF) — a mixture of stem cells, other cells, and […]
Source link : https://www.newshealth.biz/health-news/autonomy-vs-safety-in-cognitive-impairment-decision-making/ As healthcare systems across Europe deal with an increasing prevalence of cognitive impairment, family doctors are emerging as key players in assessing and supporting patients’ decision-making capacities. This was a central theme here at the 29th WONCA Europe Conference, where the European Young Family Doctors Movement (EYFDM) presented insights from a […]
Source link : https://www.newshealth.biz/health-news/psychiatric-hospital-chains-charges-schizophrenia-drug-flops-bright-light-therapy/ Acadia Healthcare, a nationwide chain of psychiatric hospitals, faces new federal charges after it just agreed to a nearly $20 million settlement over accusations it defrauded government health insurers by holding patients longer than necessary. (New York Times) Compared with usual care, a primary care intervention across practices in Germany involving […]
Source link : https://www.newshealth.biz/health-news/excitement-for-brachytherapy-in-prostate-cancer/ Adding supplemental external beam radiotherapy (EBRT) did not improve outcomes in higher-risk cancer patients who had brachytherapy, according to the long-term results of two trials. Specifically, adding EBRT did not improve biochemical failure (BF) rate or prostate cancer specific mortality (PCSM) in patients who were implanted with brachytherapy palladium 103. The […]
Source link : https://www.newshealth.biz/health-news/aflibercept-for-rop-shows-sustained-efficacy-at-age-3/ TOPLINE: A 0.4 mg dose of aflibercept in infancy to treat retinopathy of prematurity (ROP) shows sustained efficacy and safety at 3 years of age, according to research presented at EURETINA 2024. No significant ocular or systemic safety concerns were identified during follow-up, and retinal vascularization appeared complete in 80% of […]
Source link : https://www.newshealth.biz/health-news/integrated-boost-can-be-standard-after-lumpectomy/ Hypofractionated (HF) whole-breast irradiation with simultaneous integrated boost (SIB) can be considered a standard of care for adjuvant radiotherapy after breast conserving surgery, new data suggests. David Krug, MD, with the University Hospital Schleswig-Holstein in Kiel, Germany, presented the findings of the primary analysis of the HYPOSIB Trial at the American […]
Source link : https://www.newshealth.biz/health-news/low-follow-up-of-urine-dipstick-tests-in-primary-care/ Only 1 in 15 urine dipstick tests showing proteinuria in the primary care setting are followed up with albuminuria quantification testing, according to investigators. These findings expose a broad gap in screening for chronic kidney disease (CKD), which is especially concerning since newer kidney-protecting agents are more effective when prescribed earlier […]
Source link : https://www.newshealth.biz/health-news/direct-brain-a-dopamine-infusion-promising-for-parkinsons/ PHILADELPHIA — Continuous intracerebroventricular administration of an anaerobic dopamine formulation (A-dopamine) appears safe in patients with Parkinson’s disease (PD) and may avoid complications associated with levodopa, results from a first in-human trial suggest. A-dopamine induced a dose-dependent improvement in motor symptoms in refractory patients with severe levodopa complications and had a […]
Source link : https://www.newshealth.biz/health-news/chemo-can-save-lives-in-high-risk-unilateral-retinoblastoma/ TOPLINE: Adjuvant chemotherapy after removal of the affected eye improves outcomes in children with unilateral retinoblastoma who have high-risk histopathologic features that predispose them to metastases and death. METHODOLOGY: A retrospective study compared outcomes in children with unilateral retinoblastoma with high-risk histopathologic features who received adjuvant chemotherapy following enucleation vs those […]
Source link : https://www.newshealth.biz/health-news/de-intensified-therapy-misses-mark-in-hpv-positive-oropharyngeal-cancer/ Two strategies to de-escalate treatment for human papillomavirus (HPV)-positive oropharyngeal cancer failed to show noninferiority versus standard care, which “reset the bar” for future trials of de-escalation, a randomized trial showed. Standard treatment with a 70-Gy dose of radiation therapy (RT) plus cisplatin led to a 2-year progression-free survival (PFS) of […]
Source link : https://www.newshealth.biz/health-news/late-abortion-doc-missed-warnings-in-listeria-outbreak-3-5b-for-healthcare-ceos/ Welcome to the latest edition of Investigative Roundup, highlighting some of the best investigative reporting on healthcare each week. ‘America’s Abortion Doctor’ Warren Hern, MD, PhD, MPH, one of the most high-profile abortion doctors in the country, began his career in reproductive medicine before Roe v. Wade and continues it today, […]
Source link : https://www.newshealth.biz/health-news/depression-anxiety-diagnoses-have-increased-among-young-people/ Diagnoses of depression and anxiety among kids, teens, and young adults increased from 2017 to 2021, especially during the COVID-19 pandemic, according to a cohort study in Southern California. Among 1.7 million participants, the overall incidence of depression diagnosed clinically increased by 55.6% (from 1.35% to 2.10%) over this time period, […]
Source link : https://www.newshealth.biz/health-news/autoimmune-diseases-and-premature-ovarian-insufficiency/ TOPLINE: Women with premature ovarian insufficiency (POI) have a 2.6 times higher prevalence of severe autoimmune diseases before diagnosis and a 2- to 3-fold increased risk for these diseases after diagnosis. METHODOLOGY: Researchers conducted a population-based registry study including 3972 women diagnosed with spontaneous POI between 1988 and 2017. A total […]
Source link : https://www.newshealth.biz/health-news/educate-to-reduce-unnecessary-antibiotic-prescriptions/ TOPLINE: Over 90% of patients with symptoms of bronchitis, sinus infections, sore throats, colds or flu, or diarrhea expect antibiotic prescriptions. Visiting a public clinic, lower levels of education, and a lack of knowledge about the risks of taking antibiotics were linked to higher expectations of receiving antibiotics. METHODOLOGY: Researchers conducted […]
Source link : https://www.newshealth.biz/health-news/creatine-popular-exercise-supplement-could-be-grown-in-edible-plants/ Creatine has only been made in a type of tobacco plant for now Sean Gallup/Getty Images Tobacco plants have been engineered to contain creatine, a compound that is mainly stored in our muscles as a source of energy and is a popular exercise supplement. Researchers are now testing the approach in […]
Source link : https://www.newshealth.biz/health-news/hs-symptoms-eased-by-semaglutide-aided-weight-loss/ People with hidradenitis suppurativa (HS) who have overweight or obesity may benefit from adjunctive treatment with the glucagon-like peptide 1 (GLP-1) receptor agonist semaglutide (Ozempic, Wegovy), suggests research presented at the annual meeting of the European Academy of Dermatology and Venereology (EADV). In a small, nonrandomized, observational, retrospective study, semaglutide-aided weight […]
Source link : https://www.newshealth.biz/health-news/how-prior-authorization-harms-care/ Fantine Giap, MD, sat across from a 21-year-old with a rare sarcoma at the base of her skull. Despite the large tumor, nestled in a sensitive area, the Boston-based radiation oncologist could envision a bright future for her patient. She and the other members of the patient’s care team had an […]
Source link : https://www.newshealth.biz/health-news/research-consortium-on-quest-to-improve-male-infertility-tx/ A study by researchers at two academic medical centers determined which infertile men may benefit from treatment with anastrozole. They found that those with azoospermia (no sperm in their ejaculate) rarely respond to the drug while those with baseline nonazoospermia, lower levels of luteinizing hormone and follicle-stimulating hormone, and higher levels […]
Source link : https://www.newshealth.biz/health-news/topical-jaki-shows-promise-for-frontal-fibrosing-alopecia/ AMSTERDAM — For frontal fibrosing alopecia (FFA), a disease with no approved therapies, topical delgocitinib attenuated inflammation and generated hair regrowth in women in a controlled phase 2a trial. “This is an exciting avenue for FFA if the data are recapitulated in a larger population. It could be an important new […]
Source link : https://www.newshealth.biz/health-news/new-biologic-tulisokibart-beats-placebo-in-uc-trial/ The experimental monoclonal antibody tulisokibart safely induced clinical remission in a phase 2 randomized trial of moderately to severely active ulcerative colitis (UC). In one cohort of 135 patients, the primary endpoint of clinical remission occurred in 26% of those given the novel antibody to tumor necrosis factor–like cytokine 1A (TL1A) […]
Source link : https://www.newshealth.biz/health-news/how-experts-see-this-covid-and-flu-season-unfolding/ Sept. 30, 2024 – What’s the outlook for COVID-19 and flu this fall and winter? It’ll probably be a lot like last year, experts say. “We currently expect this flu season to be comparable to last year’s season,” said Adrienne Keen, PhD, of the CDC’s Center for Forecasting and Outbreak Analytics. […]
Source link : https://www.newshealth.biz/health-news/systemic-treatment-may-reduce-need-for-brain-radiotherapy/ BARCELONA — The oncologist’s goal is to provide cancer patients with the most effective and least toxic treatment available. For patients with brain metastases, whole-brain radiotherapy after stereotactic radiosurgery significantly improves tumor control, but it also has greater adverse effects on cognitive function compared with stereotactic radiosurgery alone. At the European […]
Source link : https://www.newshealth.biz/health-news/hypofractionated-radiation-safe-for-breast-reconstruction/ WASHINGTON, DC — Radiation oncologists can feel confident offering hypofractionated treatment regimens to treat breast cancer in patients who are planning breast reconstruction after mastectomy, following new findings presented at the American Society for Radiation Oncology (ASTRO) annual meeting. Over the past decade, radiation oncologists have moved toward hypofractionated regimens for […]
Source link : https://www.newshealth.biz/health-news/surgeon-operated-with-penknife-he-uses-to-cut-up-lunch/ BBC / Mark Norman Police are looking into at least 105 cases of alleged medical negligence at the NHS trust A surgeon at a crisis-hit NHS trust used a Swiss Army penknife to open up the chest of a patient because he claimed he could not find a sterile scalpel. University […]
Source link : https://www.newshealth.biz/health-news/the-places-with-the-worst-gp-shortages-in-england-revealed/ Getty Images Shortages of doctors mean the average GP in England has to care for 17% more patients than nine years ago, a BBC analysis shows. It means for every permanent GP there are more than 2,300 patients – a jump of nearly 350 since 2015, helping explain why access to […]
Source link : https://www.newshealth.biz/health-news/parkrun-events-could-boost-your-life-satisfaction/ A Parkrun event in Newcastle, UK Alan Harbottle/Alamy Taking part in Parkrun events – a free weekly activity where people are encouraged to walk or run for 5 kilometres – appears to improve life satisfaction. Parkrun is a charity that hosts events in 22 countries, including the UK, US and Australia. […]
Source link : https://www.newshealth.biz/health-news/no-improvement-in-lymphedema-with-hypofractionated-nodal-rt-for-breast-cancer/ Hypofractionated lymph node irradiation failed to reduce the frequency of lymphedema after treatment for invasive breast cancer, a randomized trial showed. A 3-week radiation therapy (RT) protocol led to a 29% incidence of perometry-assessed lymphedema as compared with 36% with a standard 5-week protocol (P=0.24). Analyses of lymphedema frequency by body […]
Source link : https://www.newshealth.biz/health-news/sharp-rise-in-heat-related-ed-visits-for-kids-in-texas/ ORLANDO — Heat-related emergency department (ED) visits soared over the last 12 years, a retrospective study at two large Texas-based children’s hospitals showed. As a proportion of total ED encounters, heat-related visits increased by 170% from 2012 (4.3 per 10,000) to 2023 (11.6 per 10,000, P=0.01), reported Taylor Merritt, MD, of […]
Source link : https://www.newshealth.biz/health-news/more-evidence-favors-a-shorter-course-of-post-mastectomy-rt/ Hypofractionated post-mastectomy radiation therapy (RT) with breast reconstruction proved noninferior to standard RT when it came to reconstruction complications, high-grade toxicity, and local control, according to results from a phase III trial. In the RT CHARM study, the reconstruction complication rate at 2 years was statistically no different, at 14% with […]
Source link : https://www.newshealth.biz/health-news/this-dad-didnt-know-his-lingering-cough-was-a-sign-of-heart-failure/ Share on PinterestFor weeks, Son Vang (center) thought his persistent cough was a lingering flu symptom. Then, a chest x-ray revealed he was experiencing heart failure. Image Provided by Son Vang After months of coughing and having the flu and pneumonia, Son Vang was hospitalized with heart failure. Over the course […]
Source link : https://www.newshealth.biz/health-news/elevating-family-medicine-is-key-for-new-aafp-president/ On September 25, family physician Jen Brull, MD, was sworn in as the new president of the American Academy of Family Physicians (AAFP). MedPage Today Washington Editor Joyce Frieden talked with Brull about what her priorities are and what challenges and opportunities she sees ahead. The interview, which was conducted online […]
Source link : https://www.newshealth.biz/health-news/hearing-loss-cognition-link-circadian-brain-changes-repetitive-head-impact-markers/ The severity of hearing loss in middle age was linked with several domains of cognitive impairment. (JAMA Network Open) Two Omani siblings who presented with early-onset parkinsonism had a mutation in SGIP1. (Cell Reports Medicine) An adaptive platform trial showed that neither memantine nor trazodone improved either functional outcome or mortality […]
Source link : https://www.newshealth.biz/health-news/simple-tips-to-get-more-in-your-diet/ Share on PinterestWhether through food or supplements, there are healthy ways to get more iron in your diet without relying on red meat. Clarkand Company/Getty Images Iron deficiency is linked to poorer brain health, heart failure, and other health concerns. A new study shows nearly 1 in 3 adults in the […]
Source link : https://www.newshealth.biz/health-news/the-ebb-and-flow-of-mentorship-in-medicine/ Lazarus is an adjunct professor of psychiatry. Reconnecting with former mentors can be both a nostalgic and enlightening experience, often offering insights into how our past influences have shaped our present. Recently, I decided to reach out to three physicians who played pivotal roles early in my career. Now in their […]
Source link : https://www.newshealth.biz/health-news/vr-headsets-in-cath-lab-icds-how-cardiologist-got-to-space/ A look at the feasibility of coronary angiography and angioplasty procedures using the Meta Quest 3 virtual reality (VR) headset. (European Heart Journal) FDA approved flurpiridaz F-18 (Flyrcado), a radiotracer for positron emission tomography myocardial perfusion imaging indicated for evaluation of myocardial ischemia and infarction in adults with known or suspected […]
Source link : https://www.newshealth.biz/health-news/neurocognitive-side-effects-of-brain-radiation-subside-for-many-analysis-shows/ Patients with brain metastases who experienced cognitive side effects following radiation therapy often fully regain cognitive function, according to a pooled analysis of three phase III trials. Of 288 patients who experienced neurocognitive failure after treatment, the pooled cumulative incidence of full cognitive recovery was about 38% at 6 months and […]
Source link : https://www.newshealth.biz/health-news/exercise-education-to-relieve-knee-oa-mixed-results-in-modeling-study/ Compared with usual care, an Australian modeling study found that a structured program of education and exercise for people with osteoarthritis (OA) of the knee wasn’t cost-effective over the long term across the entire population, though it did seem to be for those with little to no pain initially. The hypothetical […]
Source link : https://www.newshealth.biz/health-news/witnesses-in-or-give-harrowing-account-of-spleen-surgery-gone-wrong/ The Florida Department of Health has suspended the license of Thomas Shaknovsky, DO, who removed a patient’s liver instead of his spleen, contributing to his death. An emergency suspension order from the health department details how Shaknovsky severed William Bryan’s inferior vena cava, the vessel that connects the liver with the […]
Source link : https://www.newshealth.biz/health-news/fda-approves-ustekinumab-biosimilar-otulfi/ The US Food and Drug Administration has approved ustekinumab-aauz (Otulfi), a biosimilar that references Johnson & Johnson’s ustekinumab (Stelara). This is the fourth ustekinumab biosimilar approved in the United States. Like the reference product, ustekinumab-aauz is indicated for: Patients 6 years or older with moderate to severe plaque psoriasis who are […]
Source link : https://www.newshealth.biz/health-news/judge-strikes-down-georgias-6-week-abortion-ban/ A Georgia judge on Monday struck down the state’s abortion law, which took effect in 2022 and effectively prohibited abortions beyond about 6 weeks of pregnancy. Fulton County Superior Court Judge Robert McBurney wrote in his order that the law violates Georgia’s Constitution, finding that “liberty in Georgia includes in its […]
Source link : https://www.newshealth.biz/health-news/drug-free-obesity-capsule-cleared-fda-reviews-acromegaly-tx-stem-cells-reverse-t1d/ The FDA cleared a drug-free capsule for weight management in adults with a BMI of 25-40, said maker Epitomee Medical. Once swallowed, the capsule absorbs water in the stomach and creates a three-dimensional matrix to occupy volume, creating a sensation of fullness. Ascensia Diabetes Care said its 1-year Eversense 365 continuous […]
Source link : https://www.newshealth.biz/health-news/fake-online-pharmacies-sold-deadly-counterfeit-pills-prosecutors-say/ A network of illegal drug sellers based in the U.S., the Dominican Republic, and India packaged potentially deadly synthetic opioids into pills disguised as common prescription drugs and sold millions of them through fake online drugstores, federal prosecutors said Monday. At least nine people died of narcotics poisoning between August 2023 […]
Source link : https://www.newshealth.biz/health-news/food-retention-risk-low-for-glp-1-users-when-endoscopy-is-combined-with-colonoscopy/ Patients on GLP-1 receptor agonists had a low risk of food retention when an esophagogastroduodenoscopy (EGD) was combined with a colonoscopy, a small retrospective study found. Among more than 200 adults in the analysis, there were no instances of gastric food retention for the patients who underwent a combined EGD-colonoscopy, regardless […]
Source link : https://www.newshealth.biz/health-news/node-yield-trades-off-surgery-risks-in-thyroid-cancer/ Adequate lymph node yield for patients with papillary thyroid cancer is associated with longer operations, longer hospitalization, and higher risk of recurrent laryngeal nerve injury and hypocalcemia, according to results of a new retrospective database study. “The importance of adequate lymph node yield in papillary thyroid carcinoma surgery includes accurate staging […]
Source link : https://www.newshealth.biz/health-news/aap-releases-first-guidance-on-outpatient-opioid-prescribing-for-youths/ ORLANDO — The American Academy of Pediatrics (AAP) rolled out its first clinical practice guideline detailing evidence-based approaches to safely prescribe opioids for children and adolescents with acute pain in outpatient settings. The guideline describes when opioids may be indicated to treat acute pain in the pediatric population, and how to […]
Source link : https://www.newshealth.biz/health-news/in-crohns-disease-early-anti-tnf-levels-may-be-crucial/ Among patients with Crohn’s disease, a multicenter prospective cohort study found that anti-TNF therapy failed to achieve remission at 3 years in about two-thirds of cases, and that high drug concentrations early in treatment are linked to greater probability of sustained remission. “The relationship between drug concentrations, immunogenicity and clinical response […]
Source link : https://www.newshealth.biz/health-news/new-guidelines-emphasize-liver-care-in-t2d-obesity/ MADRID — Individuals with type 2 diabetes and/or obesity plus one or more metabolic risk factors are at a higher risk for metabolic dysfunction–associated steatotic liver disease (MASLD) with fibrosis and progression to more severe liver disease, stated new European guidelines that provide recommendations for diagnosis and management. “The availability of […]
Source link : https://www.newshealth.biz/health-news/doctors-less-likely-to-support-broader-access-to-cannabis-than-pain-patients/ Physicians were less likely than chronic pain patients to support expanding access to cannabis for medical purposes, according to survey findings published in JAMA Network Open. Respondents included 1,000 physicians and 1,661 people with chronic pain practicing or living in states with medical cannabis programs. For example, physicians were less likely […]
Source link : https://www.newshealth.biz/health-news/ambulance-crews-faced-crucial-delays-putting-on-ppe-in-covid/ Mark Tilley Mark Tilley worked as an ambulance technician in south-east England through the first two waves of the pandemic Ambulance crews faced crucial delays trying to save dying patients in the pandemic because of the time it took to put on protective equipment, the Covid inquiry has been told. Ambulance […]
Source link : https://www.newshealth.biz/health-news/investigational-med-for-tourette-syndrome-promising/ PHILADELPHIA — The investigational agent ecopipam reduces tic severity in children and adolescents with Tourette syndrome (TS) without exacerbating common psychiatric comorbidities, results of a new analysis suggest. As previously reported, the first-in-class dopamine-1 (D1) receptor antagonist reduced the primary endpoint of tic severity scores by 30% compared with placebo among […]
Source link : https://www.newshealth.biz/health-news/vp-nominee-medical-records-breached-queen-elizabeths-cancer-galaxy-gas-whippets/ Note that some links may require registration or subscription. A number of Veterans Affairs employees improperly accessed the medical records of vice presidential nominees JD Vance and Tim Walz over the summer, investigators found. (Washington Post) This is how Walz’s state of Minnesota factors into presidential politics surrounding insulin prices. (KFF […]
Source link : https://www.newshealth.biz/health-news/steep-fall-in-young-smokers-in-past-decade/ Getty Images Fewer than one out of every 10 young adults in the UK smoke cigarettes – a steep drop from a quarter of 18-24-year-olds 12 years ago, according to official estimates. Smoking rates among UK adults have been falling over the past decade, with nearly 12%, or six million people, […]
Source link : https://www.newshealth.biz/health-news/does-metformin-therapy-impact-cvd-in-t2d-its-complicated/ MADRID — Metformin is taken every day by more than 200 million people worldwide. Its value as a glucose-lowering agent has been established for decades. But does metformin hold similar promise for reducing rates of cardiovascular disease (CVD)? This question was the focus of a thought-provoking presentation by Simon Griffin, MD, […]
Source link : https://www.newshealth.biz/health-news/ukraines-neurosurgeons-dont-just-perform-brain-surgery/ When Russia occupied and annexed Crimea in 2014, Ukraine’s neurosurgeons saw a grim preview of the full-scale war that was yet to come. “We lost not only very big neurosurgical departments and centers in Donetsk, Mariupol, and Luhansk but also specialists and the population served,” Mykola Guk, MD, PhD, DSc, an […]
Source link : https://www.newshealth.biz/health-news/avoiding-common-diagnostic-errors-in-primary-care/ Common complaints of abdominal pain, fever, shortness of breath, or rash can signal more serious disease that should be referred to specialty care or might be related to benign conditions. Combine the vague nature of many patients’ descriptions and the pressure of short visits, and clinicians have a recipe for all […]
Source link : https://www.newshealth.biz/health-news/daratumumab-quadruplet-supported-transplant-ineligible-mm/ In the treatment of patients with newly diagnosed multiple myeloma (MM) who are not eligible for stem cell transplant or are transplant-deferred, adding subcutaneous daratumumab to bortezomib/lenalidomide/dexamethasone (D-VRd) significantly improves minimal residual disease (MRD) outcomes among patients, the first results from the phase 3 CEPHEUS trial showed. “CEPHEUS is the first […]
Source link : https://www.newshealth.biz/health-news/durable-responses-seen-with-barzolvolimab-in-csu-trial/ AMSTERDAM — Patients with chronic spontaneous urticaria (CSU) experienced early and sustained improvements in symptom scores on treatment with barzolvolimab, during the 52-week follow-up of an ongoing phase 2 study. Moreover, in the study, barzolvolimab, an anti-KIT monoclonal antibody that inhibits the activation of and depletes mast cells, induced comparable responses […]
Source link : https://www.newshealth.biz/health-news/doctors-seek-additional-training-due-to-obesity-patient-boom/ Gitanjali Srivastava, MD, professor of medicine, pediatrics & surgery, and the medical director of Obesity Medicine at Vanderbilt University School of Medicine in Nashville, Tennessee, was nearly 10 years into practicing pediatric medicine when she graduated from the obesity medicine fellowship at Massachusetts General Hospital in Boston in 2013. “We were […]
Source link : https://www.newshealth.biz/health-news/hyperandrogenic-pcos-and-pregnancy-outcomes/ TOPLINE: Women with hyperandrogenic polycystic ovary syndrome (PCOS) have lower pregnancy (29.9%) and live birth rates (20.1%) than those with nonhyperandrogenic PCOS (40.2% and 33.1%, respectively). METHODOLOGY: Researchers conducted a retrospective cohort study of 1376 participants from the PPCOS I and II trials, all meeting National Institutes of Health diagnostic criteria […]
Source link : https://www.newshealth.biz/health-news/leaving-hospital-early-linked-with-higher-drug-overdose-risk/ Patients who leave the hospital against medical advice have a 10-fold higher risk for subsequent drug overdose in the following month, a new study indicates. Overall, 1 in 30 patients with an early discharge — and 1 in 12 patients with opioid use disorder who left early — experienced an overdose […]
Source link : https://www.newshealth.biz/health-news/experts-raise-doubts-about-medical-evidence-presented-in-court/ Cheshire Police Senior doctors and scientists have told the BBC they have concerns about how crucial evidence was presented to the jury at Lucy Letby’s trials. The BBC’s File on 4 has examined how expert witnesses helped to build the case against the former nurse. The programme raises concerns about how […]
Source link : https://www.newshealth.biz/health-news/estetrol-reduces-bone-turnover-markers-in-postmenopausal-women/ CHICAGO — The levels of two bone turnover markers were significantly lower at 3 months and 1 year in postmenopausal women who received estetrol (E4) than in patients who received placebo, according to a study presented on September 12 at The Menopause Society 2024 Annual Meeting. The findings suggest that “E4 […]
Source link : https://www.newshealth.biz/health-news/covid-19-raises-hypertension-and-kidney-disease-risk-in-t1d/ TOPLINE: For patients with type 1 diabetes (T1D), a positive test or hospitalization for COVID-19 increases the risk of developing hypertension, chronic kidney disease (CKD), and diabetic ketoacidosis (DKA). METHODOLOGY: Patients with preexisting T1D who acquire SARS-CoV-2 infection are at an increased risk for severe acute COVID-19 outcomes, but the long-term […]
Source link : https://www.newshealth.biz/health-news/nccrt-wins-in-escc-trial/ SAN DIEGO — Neoadjuvant concurrent chemoradiotherapy significantly improves survival outcomes over adjuvant sequential chemoradiotherapy (ASCRT) in patients with locally advanced esophageal squamous cell carcinoma, confirmed the first randomized trial to directly compare the two approaches. Yaoyao Zhu, MD, Department of Radiation Oncology, Shanghai Pulmonary Hospital, Shanghai, China, presented the new research […]
Source link : https://www.newshealth.biz/health-news/imrt-vs-proton-therapy-for-early-prostate-cancer/ For patients with intermediate- or low-risk localized prostate cancer, intensity-modulated radiation therapy (IMRT) and proton beam therapy are both safe and effective options, according to results of the phase 3 randomized controlled PARTIQoL trial. For patients with intermediate- or low-risk localized prostate cancer, intensity-modulated radiation therapy (IMRT) and proton beam therapy are […]
Source link : https://www.newshealth.biz/health-news/race-adjustments-in-algorithms-boost-crc-risk-prediction/ TOPLINE: Accounting for racial disparities, including in the quality of family history data, enhanced the predictive performance of a colorectal cancer (CRC) risk prediction model. METHODOLOGY: The medical community is reevaluating the use of race adjustments in clinical algorithms due to concerns about the exacerbation of health disparities, especially as reported […]
Source link : https://www.newshealth.biz/health-news/altered-antibody-predicts-crohns-years-before-diagnosis/ TOPLINE: A unique glycosylation signature on circulating antibodies is detectable in blood up to 6 years before a diagnosis of Crohn’s disease and could serve as a biomarker of future development and a target for preventive strategies. METHODOLOGY: Evidence suggests that a preclinical period characterized by immunological changes precedes both symptom […]
Source link : https://www.newshealth.biz/health-news/heat-related-pediatric-ed-visits-more-than-double/ ORLANDO — Heat-related emergency department visits in children and teens more than doubled over the past decade in two Texas children’s hospitals, according to research presented at the at the American Academy of Pediatrics (AAP) 2024 National Conference. “Our study really highlights the adverse effects that can come from extreme heat, […]
Source link : https://www.newshealth.biz/health-news/fda-approves-dupilumab-as-add-on-for-copd/ The US Food and Drug Administration has approved dupilumab as an add-on maintenance therapy for adults whose chronic obstructive pulmonary disease (COPD) is inadequately controlled with inhaler therapy, according to a press release from manufacturer Regeneron. Dupilumab, a fully human monoclonal antibody sold under the brand name, Dupixent, inhibits the signaling […]
Source link : https://www.newshealth.biz/health-news/conversion-practices-tied-to-greater-symptoms-of-ptsd-suicidality/ Exposure to conversion practices was associated with increases in several mental health symptoms for sexual and gender minority individuals, according to a cross-sectional study. The analysis of more than 4,000 people revealed that self-reported exposure to both gender identity and sexual orientation conversion practices was linked with greater symptoms of post-traumatic […]
Source link : https://www.newshealth.biz/health-news/delgocitinib-approved-in-europe-for-chronic-hand-eczema/ The European Commission has approved the topical pan-JAK inhibitor delgocitinib for adults with moderate to severe hand eczema, for whom topical corticosteroids are inadequate or inappropriate, the manufacturer announced on September 23. The development is based on results from the phase 3 program of delgocitinib cream (Anzupgo), which includes the DELTA […]
Source link : https://www.newshealth.biz/health-news/mavacamten-shows-promise-in-heart-failure-with-normal-to-supranormal-ef/ There may be a future for cardiac myosin inhibitors in heart failure with preserved ejection fraction (HFpEF), according to the proof-of-concept EMBARK-HFpEF trial. An established cardiac myosin inhibitor for hypertrophic cardiomyopathy (HCM), mavacamten (Camzyos) showed potential for reducing myocardial wall stress and cardiomyocyte injury in 30 HFpEF patients with a left […]
Source link : https://www.newshealth.biz/health-news/which-viral-sleep-hacks-work-and-which-dont/ Share on PinterestSome viral ‘sleepmaxxing’ trends may help you get a better night’s sleep, while others can make insomnia worse. Sergey Mironov/Getty Images Sleepmaxxing is a social media trend that’s growing in popularity. The trend encompasses a range of advice, products, and practices aimed at improving sleep quality. Health experts say […]
Source link : https://www.newshealth.biz/health-news/falling-may-be-a-harbinger-of-dementia-in-older-adults/ Nearly 11% of older adults with an injurious fall were diagnosed with dementia 1 year later. Compared with other traumatic injuries, falls were tied to a 21% increased risk of a subsequent dementia diagnosis. Findings support cognitive screening for older adults who have a fall that involves an ED visit or […]
Source link : https://www.newshealth.biz/health-news/quality-of-life-similar-with-proton-beam-therapy-vs-imrt-for-prostate-cancer/ Patient-reported quality of life (QoL) was similar between proton beam therapy (PBT) and intensity-modulated radiation therapy (IMRT) among men with localized prostate cancer, the randomized PARTIQoL trial showed. At 24 months, the mean change in bowel function scores was -2.4 in the PBT group versus -2.2 in the IMRT group (P=0.84), […]
Source link : https://www.newshealth.biz/health-news/primary-care-intervention-might-reduce-suicide-attempts/ Following the launch of an integrated suicide prevention program across Washington state, researchers observed a 25% drop in the rate of attempted suicides in secondary analysis of a randomized stepped-wedged trial. Once a suicide screening and safety planning program was introduced to 19 primary care practices in the state, rates of […]
Source link : https://www.newshealth.biz/health-news/docs-concerned-states-abortion-pill-law-could-have-catastrophic-effects/ On Tuesday, Louisiana will become the first state in the U.S. to categorize two widely used abortion pills as “controlled dangerous substances.” Opponents argue the classification could have catastrophic impacts in a state that already has a near-total abortion ban and one of the highest maternal mortality rates in the nation. […]
Source link : https://www.newshealth.biz/health-news/the-disease-of-nine-months-caring-for-women-before-and-after-roe/ Hern is a physician specializing in abortion services. The woman sat across from me at my desk. She told me that she wanted to carry her pregnancy to term because she wanted so much to have a baby, but she couldn’t go on any longer. “I don’t feel pregnant. I feel […]
Source link : https://www.newshealth.biz/health-news/study-finds-more-heart-defects-in-kids-conceived-with-art/ Kids born via assisted reproductive technology (ART) had higher risk of congenital heart defects (CHDs), though the absolute risk difference was small, an observational Nordic study of 7.7 million children found. Major CHDs were detected in 1.84% of kids conceived after ART compared to 1.15% of spontaneously conceived kids (adjusted odds […]
Source link : https://www.newshealth.biz/health-news/case-strengthens-for-cardiac-myosin-inhibitor-in-sequoia-hcm/ Secondary efficacy analyses of the pivotal SEQUOIA-HCM trial continued to favor aficamten, supporting a potential role for another cardiac myosin inhibitor in obstructive hypertrophic cardiomyopathy (HCM). In these randomized trial analyses, aficamten significantly improved the following outcomes compared with placebo: Relief from limiting symptoms (71% vs 42% ≥1 improvement in New […]
Source link : https://www.newshealth.biz/health-news/newborns-fed-breast-milk-exclusively-in-hospital-had-lower-asthma-risk/ ORLANDO — Infants who exclusively received breast milk throughout their birth hospitalization were less likely to be diagnosed with asthma in early childhood, a database analysis suggested. Among nearly 10,000 children, bivariate analysis showed that exclusive human milk or mother’s milk was associated with a 41% lower odds of asthma in […]
Source link : https://www.newshealth.biz/health-news/in-diagnosing-knee-pain-sometimes-more-is-more/ Interim results from a randomized trial show that middle-aged patients with knee pain and suspected meniscal tears can benefit from MRI scans even in relatively simple cases. MRI findings from 760 such patients showed that 61 (8%) had issues other than plain meniscal tears that, in normal clinical practice, would alter […]
Source link : https://www.newshealth.biz/health-news/subjective-smell-improvement-after-endoscopic-sinus-surgery/ Subjective — but not objective — olfactory improvements in patients who underwent endoscopic sinus surgery for chronic rhinosinusitis with nasal polyps were maintained up to 6 months after surgery, according to results of a new study. The literature regarding olfactory improvement after endoscopic sinus surgery in these patients is conflicting, ranging […]
Source link : https://www.newshealth.biz/health-news/shared-reading-should-start-in-infancy-aap-says/ ORLANDO — The American Academy of Pediatrics (AAP) recommended that pediatricians encourage parents and caregivers to read aloud with their children beginning in infancy, according to an updated statement on literacy promotion, the first since 2014. Pre-publication releases of the policy statement and an accompanying technical report that touted the benefits […]
Source link : https://www.newshealth.biz/health-news/h-pylori-testing-did-not-reduce-gastric-cancer-incidence-mortality/ An invitation to undergo screening for Helicobacter pylori stool antigen did not reduce rates of gastric cancer incidence or mortality, according to results from a Taiwanese randomized trial. Among participants who underwent H. pylori testing along with a fecal immunochemical test (FIT) for colorectal cancer screening, the gastric cancer incidence rate […]
Source link : https://www.newshealth.biz/health-news/flipping-panel-management-on-its-head/ Fred Pelzman is an associate professor of medicine at Weill Cornell, and has been a practicing internist for nearly 30 years. He is medical director of Weill Cornell Internal Medicine Associates. In medicine, we are frequently inundated with reports on how we as a provider are doing, as well as more […]
Source link : https://www.newshealth.biz/health-news/aap-guidelines-for-safe-prescriptions/ The American Academy of Pediatrics (AAP) published its first clinical practical guidelines on opioid prescriptions for children with acute pain, outlining 12 evidence-based recommendations for safely and appropriately treating pain in young patients. The guidelines have been published alongside a technical report in Pediatrics and presented at the group’s 2024 annual meeting. […]
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