Source link : https://www.newshealth.biz/health-news/stent-like-hybrid-on-track-for-lofty-long-term-goals-in-pci/ For percutaneous coronary intervention (PCI) on de novo lesions, the DynamX bioadaptor not only matched drug-eluting stents (DES) in early performance but seemed to keep stent-related events from accruing after 6 months, according to an interim analysis from INFINITY-SWEDEHEART. In this randomized trial, the novel bioadaptor met criteria for noninferiority in […]
Tag:Health
Source link : https://www.newshealth.biz/health-news/flu-viruses-are-made-to-move-through-mucus/ Proteins on the outside of influenza A viruses are key to breaching our bodies’ mucus barriers Kateryna Kon/Science Photo Library Before viruses can infect cells, they must first get to them, often by traversing layers of the body’s protective mucus. Understanding how evolution optimised the influenza A virus for this slimy […]
Source link : https://www.newshealth.biz/health-news/filgotinib-maintains-ra-efficacy-for-3-years-no-new-safety-issues/ Filgotinib, the rheumatoid arthritis (RA) oral drug that never made it to the U.S. market but is sold across Europe, Great Britain, and Japan, remained effective for 3 years for most registration trial participants who continued in a long-term extension study, researchers said. In the so-called FINCH 4 study, ACR20 responses […]
Source link : https://www.newshealth.biz/health-news/complement-inhibitor-shows-promise-for-rare-kidney-disorder/ SAN DIEGO — Intravenous ravulizumab (Ultomiris) yielded clinically meaningful reductions in IgA nephropathy-related proteinuria in a small, mid-stage trial. The 43 patients treated with ravulizumab had a 33.2% greater reduction in average urine protein to creatinine ratio (UPCR) compared with the 22 patients on placebo (P=0.0011), reported James Tumlin, MD, of […]
Source link : https://www.newshealth.biz/health-news/what-is-the-optimal-reliever-therapy-for-difficult-to-control-asthma/ BOSTON — Inhaled corticosteroids (ICS) combined either with formoterol (Foradil) or short-acting beta-agonists (SABA) for asthma treatment were associated with reduced risks of severe exacerbations compared with bronchodilator-only relievers, a meta-analysis showed. Compared with bronchodilator-only relievers, “high certainty” evidence showed that ICS-formoterol was associated with an absolute 10.3% lower risk of […]
Source link : https://www.newshealth.biz/health-news/obesity-may-raise-risk-of-long-covid-in-youth/ Elevated body mass index (BMI) in children and young adults was associated with an increased risk of post-acute sequelae of SARS-CoV-2 infection (PASC), or long COVID, a large retrospective cohort study suggested. Those with obesity had a 25.4% increased risk of long COVID (relative risk [RR] 1.25, 95% CI 1.06-1.48) and […]
Source link : https://www.newshealth.biz/health-news/flu-viruses-are-made-to-move-through-mucous/ Proteins on the outside of influenza A viruses are key to breaching our bodies’ mucous barriers Kateryna Kon/Science Photo Library Before viruses can infect cells, they must first get to them, often by traversing layers of the body’s protective mucous. Understanding how evolution optimised the influenza A virus for this slimy […]
Source link : https://www.newshealth.biz/health-news/study-medicares-competitive-bidding-program-not-a-danger-to-copd-oxygen-users/ The Medicare Competitive Bidding Program (CBP) appeared to reduce spending without impacting oxygen prescriptions for beneficiaries with chronic obstructive pulmonary disease (COPD), a study showed. Implementation of the CBP in two cohorts was not associated with a greater change in probability of a new oxygen prescription (difference in differences [DID] estimate […]
Source link : https://www.newshealth.biz/health-news/a-look-at-the-supreme-courts-upcoming-term/ Gostin is an expert in health law and policy. Radhakrishnan is a law fellow. In the last few years, the Supreme Court has significantly undermined public health powers related to pandemic threats, gun violence, and the environment, while upending decades-old precedents to severely limit reproductive rights and disempower health, safety, and […]
Source link : https://www.newshealth.biz/health-news/hospitals-ai-transcription-tool-invents-things-no-one-ever-said-researchers-say/ Tech behemoth OpenAI has touted its artificial intelligence-powered transcription tool Whisper as having near “human level robustness and accuracy.” But Whisper has a major flaw: It is prone to making up chunks of text or even entire sentences, according to interviews with more than a dozen software engineers, developers, and academic […]
Source link : https://www.newshealth.biz/health-news/more-evidence-avatar-therapy-quiets-auditory-hallucinations/ A novel digital treatment designed to reduce the frequency of auditory hallucinations and associated distress in patients with psychosis has been shown to be safe and effective, results from the largest study of avatar therapy to date show. The therapy allows patients to interact with a “digital embodiment” of the voice […]
Source link : https://www.newshealth.biz/health-news/remote-patient-monitoring-is-a-great-idea-but-whats-the-best-way-to-use-it/ Fred Pelzman is an associate professor of medicine at Weill Cornell, and has been a practicing internist for nearly 30 years. He is medical director of Weill Cornell Internal Medicine Associates. I am a huge fan of remote patient monitoring. As I’ve written about before, patients spend a tiny fraction of […]
Source link : https://www.newshealth.biz/health-news/daylight-saving-ends-next-weekend-how-to-prepare-for-the-potential-health-effects/ The good news: You will get a glorious extra hour of sleep. The bad: It’ll be dark as a pocket by late afternoon for the next few months in the U.S. Daylight saving time ends at 2 a.m. local time next Sunday, November 3, which means you should set your clock […]
Source link : https://www.newshealth.biz/health-news/fda-requests-more-info-on-pharmathers-ketamine-application/ The US Food and Drug Administration (FDA) has issued a complete response letter (CRL) to PharmaTher citing deficiencies in the company’s abbreviated new drug application for racemic ketamine (Ketarx), the company said. “The deficiencies cited in the CRL are classified as minor,” the company said in a statement. “The FDA requested […]
Source link : https://www.newshealth.biz/health-news/fertility-rate-in-england-and-wales-drops-to-new-low/ Getty Images Just over 591,000 babies were born in the UK last year – the lowest number in four decades Women in England and Wales had an average of 1.44 children between 2022 and 2023, the lowest rate on record. Only 591,072 babies were born in 2023, fewer than in any […]
Source link : https://www.newshealth.biz/health-news/weight-loss-drugs-dont-reduce-oocyte-retrieval/ The use of glucagon-like peptide 1 (GLP-1) agonists within a year had no apparent effect on the number of oocytes retrieved in controlled ovarian hyperstimulation (COH), based on data from 73 patients in a multicenter study. Obesity rates continue to rise in women of reproductive age and many women are using […]
Source link : https://www.newshealth.biz/health-news/fda-announces-recall-of-more-than-7000-bottles-of-duloxetine/ The US Food and Drug Administration (FDA) has announced a voluntary manufacturer-initiated recall of more than 7000 bottles of duloxetine delayed-release capsules due to unacceptable levels of a potential carcinogen. Duloxetine (Cymbalta) is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, chronic musculoskeletal pain, and […]
Source link : https://www.newshealth.biz/health-news/trump-and-eugenics-doctors-poised-to-strike-laced-pizza-sickens-dozens/ Note that some links may require registration or subscription. When former president Donald Trump talks about the “bad genes” of undocumented immigrants, experts hear rhetoric from the eugenics movement. (STAT) If elected to a second term, Trump said he would let Robert F. Kennedy Jr. “go wild” on health, medicine, and […]
Source link : https://www.newshealth.biz/health-news/maternal-bmi-and-eating-disorders-tied-to-mental-health-in-kids/ TOPLINE: Children of mothers who had obesity or eating disorders before or during pregnancy may face higher risks for neurodevelopmental and psychiatric disorders. METHODOLOGY: Researchers conducted a population-based cohort study to investigate the association of maternal eating disorders and high prepregnancy body mass index (BMI) with psychiatric disorder and neurodevelopmental diagnoses […]
Source link : https://www.newshealth.biz/health-news/pcps-less-likely-to-prescribe-nonantibiotic-options-for-uti/ While primary care physicians are generally comfortable prescribing vaginal estrogen therapy for recurrent urinary tract infections (UTIs), other nonantibiotic prophylactic options remain significantly underutilized, according to new research that highlights a crucial gap in antibiotic stewardship practices among primary care physicians. UTIs are the most common bacterial infection in women of […]
Source link : https://www.newshealth.biz/health-news/can-stem-cells-relieve-chronic-low-back-pain/ TOPLINE: Allogeneic bone marrow–derived mesenchymal stromal cells (BM-MSCs) are safe but do not show efficacy in treating intervertebral disc degeneration (IDD) in patients with chronic low back pain. METHODOLOGY: The RESPINE trial assessed the efficacy and safety of a single intradiscal injection of allogeneic BM-MSCs in the treatment of chronic low […]
Source link : https://www.newshealth.biz/health-news/should-pharmacists-lead-bp-control-teams/ Current efforts to control high blood pressure (BP) are failing in the United States and globally. The first World Health Organization (WHO) global report on hypertension found that, globally, only 54% of adults with hypertension are diagnosed, 42% get treatment, and just 21% have their hypertension controlled. In the United States, […]
Source link : https://www.newshealth.biz/health-news/us-veterans-may-face-nearly-triple-the-risk-for-skin-cancer/ US veterans were nearly three times more likely to develop skin cancer than the general population, according to a large cross-sectional analysis of recent national data. Sepideh Ashrafzadeh, MD “US veterans are known to have increased risk of cancers and cancer morbidity compared to the general US population,” one of the […]
Source link : https://www.newshealth.biz/health-news/can-we-repurpose-obesity-drugs-to-reverse-liver-disease/ Metabolic dysfunction–associated steatotic liver disease (MASLD) has become the most common liver disease worldwide, with a global prevalence of 32.4%. Its growth over the past three decades has occurred in tandem with increasing rates of obesity and type 2 diabetes — two cornerstones of MASLD. Higher rates of MASLD and metabolic […]
Source link : https://www.newshealth.biz/health-news/doctor-who-urinated-in-gosport-hospital-sink-struck-off/ Getty Images Two colleagues said they had seen Dr Graham Holmes urinating into a sink A doctor found to have urinated in a consultation room’s sink and failed to adhere to restrictions on his registration has been struck off. Graham Holmes worked as a locum consultant in Hampshire, Dorset, Greater Manchester […]
Source link : https://www.newshealth.biz/health-news/humans-and-carbs-a-complicated-800000-year-relationship/ Trying to reduce your carbohydrate intake means going against nearly a million years of evolution. Humans are among a few species with multiple copies of certain genes that help us break down starch — carbs like potatoes, beans, corn, and grains — so that we can turn it into energy our […]
Source link : https://www.newshealth.biz/health-news/rising-stroke-rates-in-californians-with-scd/ TOPLINE: Stroke rates in Californians with sickle cell disease (SCD) have increased in both children and adults in the post-STOP era. The cumulative incidence of first ischemic stroke was 2.1% by age 20 and 13.5% by age 60. METHODOLOGY: Researchers analyzed data from the California Department of Health Care Access and […]
Source link : https://www.newshealth.biz/health-news/study-compares-methods-for-treating-recalcitrant-keloids/ Punch excision (PE) followed by immediate cryotherapy could be a viable and simpler alternative to core excision (CE) for the treatment of recalcitrant keloids, according to the results of a small retrospective study. Jinwoong Jung, MD The method “offers similar efficacy, faster healing, and fewer complications,” one of the study authors, […]
Source link : https://www.newshealth.biz/health-news/upadacitinib-effective-long-term-for-ad-in-adolescents/ TOPLINE: Long-term treatment with upadacitinib in adolescents with moderate to severe atopic dermatitis (AD) demonstrated sustained efficacy and an acceptable safety profile through 76 weeks across three phase 3 trials. METHODOLOGY: Researchers conducted three double-blind, placebo-controlled phase 3 randomized clinical trials (Measure Up 1, Measure Up 2, and AD Up) involving […]
Source link : https://www.newshealth.biz/health-news/empagliflozin-effects-subside-with-discontinuation/ SAN DIEGO — The significant kidney and cardiovascular benefits people with chronic kidney disease (CKD) show over 2 years of treatment with empagliflozin begin to subside within about a year after treatment discontinuation, suggesting the need for ongoing treatment. “We know that empagliflozin is safe we know it works and now […]
Source link : https://www.newshealth.biz/health-news/dupilumab-proves-effective-in-chronic-spontaneous-urticaria/ BOSTON — Add-on dupilumab (Dupixent) significantly reduced itching and urticaria in patients with chronic spontaneous urticaria (CSU) whose symptoms were uncontrolled with H1-antihistamine therapy. The phase III LIBERTY-CUPID study C showed that among children and adults randomized to receive either dupilumab or placebo added to standard-of-care (SoC) H1 antihistamines, those receiving […]
Source link : https://www.newshealth.biz/health-news/interim-align-data-atrasentan-cuts-proteinuria-in-iga-nephropathy/ SAN DIEGO — A novel drug significantly reduced IgA nephropathy-related proteinuria, according to interim findings of the ALIGN study. In the phase III trial, among 270 patients with the rare kidney disorder, those on atrasentan had a 36.1 percentage point (95% CI -44.6 to -26.4, PAmerican Society of Nephrology Kidney Week […]
Source link : https://www.newshealth.biz/health-news/this-was-not-a-rare-or-exceptional-circumstance-what-we-heard-this-week/ “It became clear to me that this was not a rare or exceptional circumstance, but that the overwhelming majority of youth receiving this care were happy with it.” — Kristina Olson, PhD, of Princeton University, reporting that most youth who received gender-affirming care had no regrets. “We really should be looking […]
Source link : https://www.newshealth.biz/health-news/mortality-rates-from-early-onset-crc-have-risen-considerably/ PHILADELPHIA — The mortality rate of early-onset colorectal cancer (EO-CRC) has increased considerably across the United States over the past two decades, with the effects most pronounced in those aged 20-44 years, according to a new analysis of the two largest US mortality databases. Data from the US Centers for Disease […]
Source link : https://www.newshealth.biz/health-news/pbm-math-big-chains-get-23-55-for-blood-pressure-rx-as-small-drugstores-get-1-51/ CUTHBERT, Ga. — While customers at Adams Family Pharmacy picked up their prescriptions on a hot summer day, some stopped in for coffee, ice cream, homemade cake, or cookies. It wasn’t a bake sale, but the sweets bring extra revenue as pharmacist and co-owner Nikki Bryant, PharmD, works to achieve profitability […]
Source link : https://www.newshealth.biz/health-news/going-beyond-hearing-aids-for-equal-care-access/ Huang is a family physician who is fluent in American Sign Language (ASL). As a physician who is hard of hearing, I was excited to learn about FDA’s authorization of Apple’s newest AirPods, which will come with the capability to convert into hearing aids. If the AirPods live up to their […]
Source link : https://www.newshealth.biz/health-news/dapagliflozin-safe-and-effective-in-ckd-stages-4-and-5/ SAN DIEGO — Dapagliflozin provides significant benefits in the treatment of chronic kidney disease (CKD) even when initiated in patients with the most severe stages of the disease who are typically excluded from clinical trials, new research shows. In patients with CKD stage 4-5, dapagliflozin plus integrated CKD care improved total […]
Source link : https://www.newshealth.biz/health-news/alternative-pathway-inhibition-makes-good-in-iga-nephropathy/ SAN DIEGO — There was a clinically meaningful reduction in proteinuria with iptacopan (Fabhalta), and a confirmed clinical benefit of alternative pathway inhibition, in a rare kidney disorder, according to an interim analysis of the APPLAUSE-IgAN study. In the phase III study, among the first 250 patients with IgA nephropathy who […]
Source link : https://www.newshealth.biz/health-news/did-cdc-recommend-a-second-dose-of-the-new-covid-vaccine-for-all-adults/ The 24-hour news cycle is just as important to medicine as it is to politics, finance, or sports. At MedPage Today, new information is posted daily, but keeping up can be a challenge. As an aid for our readers, and for a little amusement, here is a 10-question quiz based on […]
Source link : https://www.newshealth.biz/health-news/pediatric-febrile-uti-may-hurt-kidney-function/ SAN DIEGO — Antibiotic prophylaxis may help to protect kidneys of kids with vesicoureteral reflux during febrile urinary tract infections (UTIs), according to another look at the RIVUR trial. Among 188 children with this common congenital anomaly, more than one febrile UTI during the 2-year study period had an average eGFR […]
Source link : https://www.newshealth.biz/health-news/metformin-and-congenital-abnormalities-deprescribing-in-patients-with-dementia/ TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center in El Paso, look at the top medical stories of the week. This week’s topics include […]
Source link : https://www.newshealth.biz/health-news/aki-intervention-falls-short-of-improving-patient-outcomes/ SAN DIEGO — A strategy to improve the management of hospitalized patients with acute kidney injury (AKI) through rapid personalized recommendations made by a dedicated kidney action team facilitates testing and other measures, but ultimately falls short in improving clinical outcomes, a randomized, multicenter study shows. Although recommendations from a dedicated […]
Source link : https://www.newshealth.biz/health-news/im-a-black-trauma-surgeon-ending-gun-violence-demands-fighting-for-racial-justice/ Williams is a trauma surgeon. Eighteen months ago, we buried my cousin — shot dead in front of his house. In the heat of my congressional campaign, time to mourn conflicted with fundraising, meet-and-greets, and securing endorsements. On the campaign trail, running on a gun safety platform, I shared stories about […]
Source link : https://www.newshealth.biz/health-news/limited-kidney-benefits-with-finerenone-in-heart-failure/ SAN DIEGO — In patients with heart failure, treatment with finerenone provides some benefits in reducing the risk for macroalbuminuria. However, no significant changes are observed in estimated glomerular filtration rate (eGFR)-based kidney outcomes, an analysis of the recently published FINEARTS-HF trial shows. “Among patients with heart failure with mildly reduced […]
Source link : https://www.newshealth.biz/health-news/precision-medicine-approach-shows-promise-for-anaplastic-thyroid-cancer/ Two prospective trials of immunotherapy in thyroid cancer, one of them negative, provided support for precision-medicine approaches that include immunotherapy. A trial of atezolizumab (Tecentriq) and mutation-selected targeted agents led to better overall survival (OS) as compared with historical results in anaplastic thyroid carcinoma (ATC), reaching a maximum of 43 months […]
Source link : https://www.newshealth.biz/health-news/at-least-75-people-sickened-as-deadly-mcdonalds-e-coli-outbreak-expands/ A deadly outbreak of Escherichia coli poisoning tied to McDonald’s Quarter Pounders has expanded, with at least 75 people sick in 13 states, federal health officials said Friday. A total of 22 people have now been hospitalized, and two have developed a dangerous kidney disease complication, the CDC said. One person […]
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FDA Approves Novel Treatment for UTIs
Source link : https://www.newshealth.biz/health-news/fda-approves-novel-treatment-for-utis/ The FDA approved oral sulopenem etzadroxil and probenecid (Orlynvah) to treat uncomplicated urinary tract infections (uUTIs) caused by certain bacteria in women with limited or no alternative oral antibacterial treatment options, the agency said Friday. The drug is a combination of a penem antibacterial (sulopenem etzadroxil) and a renal tubular transport […]
Source link : https://www.newshealth.biz/health-news/upadacitinib-shows-long-term-benefits-in-teens-with-atopic-dermatitis/ Treatment with the Janus kinase (JAK) inhibitor upadacitinib (Rinvoq) showed a favorable long-term benefit-risk profile through 76 weeks in adolescents with moderate to severe atopic dermatitis, an analysis of three phase III randomized trials showed. At week 76 in the Measure Up 1, Measure Up 2, and AD Up trials, 84-89% […]
Source link : https://www.newshealth.biz/health-news/a-moral-code-ethical-dilemmas-in-medicine/ Listen and subscribe to Anamnesis by searching for MedPod Today on Apple and Spotify so you don’t miss the next episode. Amy Ho: Hey everyone and welcome back to Anamnesis by MedPage. Now, I’m Amy Ho: ER doctor, lover of stories, and your humble podcast host. We are back for another […]
Source link : https://www.newshealth.biz/health-news/algorithm-may-be-able-to-predict-hcc-risk-in-advanced-chronic-liver-disease/ A risk stratification algorithm may be able to predict which patients with advanced chronic liver disease are at risk of developing hepatocellular carcinoma (HCC), according to a large-scale multicenter study. Among more than 2,300 patients with advanced chronic liver disease, a six-parameter algorithm, known as PLEASE, indicated that patients stratified as […]
Source link : https://www.newshealth.biz/health-news/novel-research-details-incidence-of-ploidy-abnormalities/ DENVER — Genetic testing and algorithms revealed that over 1% of more than 96,000 blastocyst-stage embryos had ploidy abnormalities, or atypical numbers of chromosomes. In total, ploidy abnormalities were detected in 1.15% (CI 95% 1.0-1.2) of embryos after clinical pre-implantation genetic testing, of which 0.9% were triploidy (embryos with an extra […]
Source link : https://www.newshealth.biz/health-news/personalized-breast-cancer-treatment-insights-into-hpv-in-men-exercise-and-cancer/ Surgical innovations for breast cancer have led to personalized treatment choices that are more complex than lumpectomy versus mastectomy. (Mayo Clinic) Using a breast cancer’s genetic signature to guide treatment showed promise for improving outcomes in a phase III trial. (The BMJ) Use of artificial intelligence guidance did not improve the […]
Source link : https://www.newshealth.biz/health-news/mhra-warns-of-weight-loss-drug-side-effects/ The Medicines and Healthcare products Regulatory Agency (MHRA) has reminded healthcare professionals to warn patients about common and serious side effects associated with glucagon-like peptide-1 receptor agonists (GLP-1RAs). Simultaneously, the House of Lords food, diet, and obesity committee declared a public health emergency on obesity and diet-related diseases and recommended a […]
Source link : https://www.newshealth.biz/health-news/stroke-survivors-with-afib-could-start-doacs-earlier/ It was safe to start direct oral anticoagulant (DOAC) therapy without delay after acute ischemic stroke in people with atrial fibrillation (Afib), according to the OPTIMAS randomized trial. Stroke survivors randomized to early or delayed DOAC initiation had the same 3.3% incidence of composite recurrent ischemic stroke, symptomatic intracranial hemorrhage, unclassifiable […]
Source link : https://www.newshealth.biz/health-news/kidney-transplant-trouble-spelled-out-for-newer-rejection-episode-categories/ SAN DIEGO — Kidney transplant patients who shifted into newly recognized microvascular inflammation categories under revised definitions had an intermediate risk of poor allograft outcomes, a large study showed. Researchers examined outcomes among more than 6,700 kidney transplant recipients, looking at two categories added in 2022 to the benchmark diagnostic framework […]
Source link : https://www.newshealth.biz/health-news/online-ivf-injection-training-boosts-patient-confidence/ DENVER — Online training about the details of in vitro fertilization (IVF) boosts patient confidence about managing the process more than in-person training, according to research presented on October 21 at the 2024 Scientific Conference & Expo of the American Society for Reproductive Medicine (ASRM). “It can take quite a bit […]
Source link : https://www.newshealth.biz/health-news/traumatic-fractures-surge-among-us-mountain-bikers/ TOPLINE: Mountain biking–related fractures have surged since 2013 in the United States, with wrist and radius or ulnar injuries being most common; adult men are at the highest risk for trunk fractures, and being thrown from the bike is the mechanism most likely to result in a fracture. METHODOLOGY: Researchers analyzed […]
Source link : https://www.newshealth.biz/health-news/europes-polio-free-status-is-not-a-done-deal/ The European Regional Commission for the Certification of Poliomyelitis Eradication (RCC) has warned that Europe’s long-held polio-free status could be at risk due to inadequately enforced and outdated action plans for potential outbreaks. Vaccine manufacturing premises are a specific concern. “While there is notable progress with implementation of the WHO Global […]
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Travel Nurses Still in Demand
Source link : https://www.newshealth.biz/health-news/travel-nurses-still-in-demand/ Ashly Doran has worked at seven hospitals in four states since she graduated from nursing school in 2020. No, she isn’t job-hopping. Her travel nursing assignments have ranged from level 1 trauma center emergency rooms in big cities to small medical-surgical units in the suburbs. After each 13-week assignment, Doran packs […]
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A Case of Broca’s Aphasia
Source link : https://www.newshealth.biz/health-news/a-case-of-brocas-aphasia/ Schwartz is a neurosurgeon. On Sept. 14, 2000, at the age of 72, Lester Schwartz, a psychoanalyst working in New York City, underwent a simple operation for a benign fatty tumor in his stomach. He woke up the next morning in the hospital and realized he had lost his ability to […]
Source link : https://www.newshealth.biz/health-news/new-data-on-doac-initiation-after-stroke-in-af-final-word/ Abu Dhabi, UAE — The long-standing debate as to when to start anticoagulation in patients with an acute ischemic stroke and atrial fibrillation (AF) looks as though it’s settled. Results of the OPTIMAS trial, the largest trial to address this question, showed that initiation of a direct oral anticoagulant (DOAC) within […]
Source link : https://www.newshealth.biz/health-news/glp-1s-may-protect-against-progression-to-cirrhosis-in-masld/ TOPLINE: For patients with metabolic dysfunction–associated steatotic liver disease (MASLD) and diabetes, treatment with a glucagon-like peptide 1 receptor agonist (GLP-1 RA) may protect against progression to cirrhosis and mortality; however, the protective benefits do not extend to patients who already have cirrhosis, a new study found. METHODOLOGY: GLP-1 RAs reduce […]
Source link : https://www.newshealth.biz/health-news/uncertainty-over-balloon-guide-catheter-use-for-mt-in-stroke/ Abu Dhabi, UAE — Use of a balloon guide catheter was associated with worse functional outcomes than use of a conventional guide catheter in stroke patients with large vessel anterior occlusions undergoing thrombectomy within 24 hours of symptom onset However, the PROTECT-MT trial was stopped early, and the small sample size […]
Source link : https://www.newshealth.biz/health-news/who-growth-curves-misclassify-inuit-children/ Using population-specific growth curves for Inuit children could promote the appropriate diagnosis of microcephaly and avoid overdiagnosis, according to a new study. Inuit children from Nunavut, Canada, may appear to have high rates of macrocephaly, based on World Health Organization (WHO) growth chart measurements. But in many cases, no pathology is […]
Source link : https://www.newshealth.biz/health-news/digital-tool-may-help-neurologists-assess-steroid-toxicity/ SAVANNAH, Ga. — A digital tool to help neurologists assess steroid toxicity in patients with myasthenia gravis (MG) demonstrated sensitivity in distinguishing between different doses and durations of steroid exposure in a retrospective, real-world study. The Glucocorticoid Toxicity Index-Metabolic Domains (GTI-MD), an abbreviated version of the GTI (Steritas), used weighted, standardized […]
Source link : https://www.newshealth.biz/health-news/veterans-affairs-hailed-as-a-bright-spot-in-als-care/ SAVANNAH, GEORGIA — Teamwork and transdisciplinary collaboration create an effective system of care for amyotrophic lateral sclerosis (ALS), ensuring improved health both for patients and clinicians alike, said one expert. In a plenary address on October 17 at the American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) 2024, Ileana Howard, MD, […]
Source link : https://www.newshealth.biz/health-news/can-vaccines-slash-global-antibiotic-use-who-says-yes/ Expanding vaccine use has the potential to reduce the administration of up to 2.5 billion doses of antimicrobials per year, making a significant contribution to the fight against antimicrobial resistance (AMR), one of the greatest public health challenges worldwide. This information is included in a new World Health Organization (WHO) report […]
Source link : https://www.newshealth.biz/health-news/onabotulinumtoxina-approved-for-treatment-of-platysma-bands/ The US Food and Drug Administration (FDA) has approved onabotulinumtoxinA (Botox Cosmetic) for temporary improvement in the appearance of moderate to severe platysma bands in adults. According to a press release from Allergan Aesthetics, which developed onabotulinumtoxinA, by injecting along the jawline and the vertical bands connecting the jaw and neck […]
Source link : https://www.newshealth.biz/health-news/pioneering-eyebrow-surgery-removes-large-brain-tumours/ BBC Doreen Adams said she was grateful to have been able to receive the new surgery Pioneering surgery to remove large brain tumours through the eyebrows of patients has been successfully carried out in Scotland. In what has been described as a “world first”, NHS Grampian said tumours the size of […]
Source link : https://www.newshealth.biz/health-news/old-line-rheum-drugs-lose-luster-in-jia/ Use of conventional synthetic drugs to treat juvenile idiopathic arthritis (JIA) fell by half during 2000-2022, as targeted therapies became increasingly popular, analysis of commercial insurance claims showed. Whereas 89.5% of new prescriptions for disease-modifying anti-rheumatic drugs (DMARDs) in 2000 were for old-line agents, by the end of the period such […]
Source link : https://www.newshealth.biz/health-news/no-evidence-of-human-to-human-h5n1-transmission-in-missouri-case/ There’s no evidence of human-to-human transmission of H5N1 bird flu among patients and healthcare workers in Missouri, the CDC said during a press briefing today. None of the six healthcare workers who developed respiratory symptoms after coming into contact with an H5N1-infected patient was infected with the virus; one tested negative […]
Source link : https://www.newshealth.biz/health-news/acip-votes-to-harmonize-dosing-and-interval-for-meningococcal-b-vaccines/ The CDC’s Advisory Committee on Immunization Practices (ACIP) on Thursday unanimously endorsed revising the dosing and interval of the meningococcal group B vaccine MenB-4C (Bexsero). In a 15-0 vote, ACIP recommended that MenB-4C be administered as a two-dose series at 0 and 6 months when given to healthy adolescents and young […]
Source link : https://www.newshealth.biz/health-news/use-of-lidocaine-during-vaginoscopic-hysteroscopy-guided-biopsy-reduced-pain/ DENVER — For women undergoing endometrial biopsy using vaginoscopic hysteroscopy, intrauterine lidocaine significantly decreased pain during and after the procedure, a double-blinded randomized trial showed. Women randomized to lidocaine reported significantly less pain using a visual analogue scale (VAS) at hysteroscope insertion; during the biopsy; and at 10, 30, and 60 […]
Source link : https://www.newshealth.biz/health-news/ozempic-linked-with-lower-risk-of-alzheimers-diagnosis/ Semaglutide was linked with reduced Alzheimer’s risk among people with diabetes. The drug outperformed seven other diabetes medications in an observational study. GLP-1 drugs may target multiple Alzheimer’s pathways, including inflammation. Semaglutide (Ozempic) was tied to a reduced risk of Alzheimer’s disease diagnoses in people with type 2 diabetes, observational data […]
Source link : https://www.newshealth.biz/health-news/glp-1-drugs-tied-to-reduced-risk-of-uterine-fibroids/ DENVER — In women with type 2 diabetes, use of GLP-1 receptor agonists was associated with a reduced risk of new-onset uterine fibroids compared with other antidiabetic agents, a retrospective cohort study suggested. Among patients who took at least two doses of medication, GLP-1 receptor agonists were associated with a significantly […]
Source link : https://www.newshealth.biz/health-news/fda-warns-companies-over-products-made-with-amniotic-fluid/ The FDA has sent warning letters to two companies regarding their amniotic membrane- and fluid-derived PalinGen products, charging they should be regulated as drugs and biologics. One of the letters, addressed to Phoenix, Arizona-based Pinnacle Transplant Technologies’ president and chief executive officer Roger W. Rose, claimed the company distributed products derived […]
Source link : https://www.newshealth.biz/health-news/the-case-against-white-coats-addicted-to-nasal-spray-get-ready-for-a-shift-with-me/ The following contains links to social media websites including X, TikTok, Instagram, Facebook, and LinkedIn. “Just because I don’t wear a white coat doesn’t make me any less of a doctor,” said internist @dr.evab, advocating for comfort and confidence over traditional white coat uniforms. “Who says surgeons and anesthesiologists can’t get […]
Source link : https://www.newshealth.biz/health-news/uva-health-surgeons-sound-alarm-on-upcoding/ More light has been shed on allegations of a toxic work environment at the University of Virginia School of Medicine and UVA Health. About a year ago, surgeons had raised concerns that they were pressured by leadership to upcode in an effort to bring in more money, according to The Daily […]
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Doctors warn people not to ignore rash
Source link : https://www.newshealth.biz/health-news/doctors-warn-people-not-to-ignore-rash/ Getty Images Scabies can lead to secondary skin infections, if not treated. People are being told not to ignore an itchy rash, with GPs in England reporting a spike in scabies – the highly infectious skin infestation. The condition is caused by a mite which burrows under the skin to lay […]
Source link : https://www.newshealth.biz/health-news/emerging-fungal-infections-demand-all-out-approach/ As the number of drug-resistant and other troublesome tinea infections grows, perhaps the only certainty is that these are not the tinea subtypes that most providers studied in medical school. As dermatologists, public health officials, and infectious disease specialists scramble to raise awareness about prevention and treatment, challenges ranging from a […]
Source link : https://www.newshealth.biz/health-news/docs-covid-spending-bust-plastic-surgeon-faces-10m-suit-letby-loses-appeal/ Washington state dermatologist William Philip Werschler, MD, has been indicted on charges that he used $1.5 million in COVID relief funds to buy sports cars, real estate, and pay off personal debt. (KREM) A woman has filed a $10 million lawsuit against New York plastic surgeon Ammar Mahmoud, MD, alleging he […]
Source link : https://www.newshealth.biz/health-news/how-much-should-doctors-give-to-charity/ This question we are going to address today is a loaded and very personal one. The question is: How much should we give to charity? Everyone must determine the answer to this for themselves. However, one could argue that as high-income earners, doctors have a greater obligation. My wife Selenid and […]
Source link : https://www.newshealth.biz/health-news/medicaid-expansion-linked-to-better-survival-in-aggressive-breast-cancer/ Women with newly diagnosed hormone receptor (HR)-negative, HER2-positive breast cancer were more likely to receive timely treatment and have longer survival in states that participated in Medicaid expansion under the Affordable Care Act, a nationwide study showed. For over 31,000 women with this aggressive breast cancer, Medicaid expansion was associated with […]
Source link : https://www.newshealth.biz/health-news/50-years-after-city-halted-prison-medical-testing-families-seek-reparations/ Fifty years ago, Philadelphia prison officials ended a medical testing program that had allowed an Ivy League researcher to conduct human testing on incarcerated people, many of them Black, for decades. Now, survivors of the program and their descendants want reparations. Thousands of people at Holmesburg Prison were exposed to painful […]
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Potential Drivers of LCINS
Source link : https://www.newshealth.biz/health-news/potential-drivers-of-lcins/ The incidence of lung cancer in never-smokers (LCINS) is increasing, and experts think climate change may be driving this. LCINS differs histologically and epidemiologically from smoking-related cancers, occurring almost always as adenocarcinomas and mostly affecting women and individuals of Asian ancestry, according to a study published in Nature Reviews Clinical Oncology […]
Source link : https://www.newshealth.biz/health-news/electric-skin-patch-could-keep-wounds-free-of-infection/ Staphylococcus epidermidis bacteria can enter the body via skin wounds Scott Camazine/Alamy A patch that zaps the skin with electrical pulses could be used before or after surgery to prevent bacteria on the skin from causing blood poisoning, reducing our reliance on antibiotics. Staphylococcus epidermidis bacteria usually live harmlessly on human […]
Source link : https://www.newshealth.biz/health-news/epa-imposes-stricter-standards-to-protect-kids-from-lead-paint-exposure/ Two weeks after setting a nationwide deadline for removal of lead pipes, the Biden administration is imposing strict new limits on dust from lead-based paint in older homes and childcare facilities. A final rule announced Thursday by the Environmental Protection Agency (EPA) sets limits on lead dust on floors and window […]
Source link : https://www.newshealth.biz/health-news/more-evidence-ties-semaglutide-to-reduced-alzheimers-risk/ A new study provides real-world evidence to support the potential repurposing of glucagon-like peptide 1 receptor agonists (GLP-1 RAs), used to treat type 2 diabetes and obesity, for prevention of Alzheimer’s disease (AD). Adults with type 2 diabetes who were prescribed the GLP-1 RA semaglutide had a significantly lower risk for […]
Source link : https://www.newshealth.biz/health-news/anatomy-of-a-suicide-crisis-life-after-abuse/ Lee is a psychiatry resident. Content warning: discussion of suicide & domestic violence. If you are in crisis, text or call 988. “Do you know what it is that I fear the most? When I yearn for something so much in a world so hopeless that it weakens my heart.” — […]
Source link : https://www.newshealth.biz/health-news/mutational-profile-can-help-guide-waldenstrom-treatment/ NEW YORK — In the wake of details about the molecular pathophysiology of Waldenström macroglobulinemia (WM), an expert gave an update on current and expanding options for treatment. Most importantly, determining the mutational status of patients with WM has become a first or early step in guiding first- and second-line therapies, […]
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CAR T Not a Clear Winner
Source link : https://www.newshealth.biz/health-news/car-t-not-a-clear-winner/ NEW YORK — In a three-way debate on whether to prioritize chimeric antigen receptor (CAR) T-cell therapy, bispecific antibodies (BsAbs), or one of the novel oral targeted therapies for relapsed/refractory follicular lymphoma (R/R FL), no expert conceded. Acknowledging that hers was the weakest position, even the specialist who defended novel targeted […]
Source link : https://www.newshealth.biz/health-news/blood-tests-for-alzheimers-are-hereare-clinicians-ready/ With the approval of anti-amyloid monoclonal antibodies to treat early-stage Alzheimer’s disease (AD), the need for accurate and early diagnosis is crucial. Blood-based biomarkers offer a promising alternative to amyloid PET scans and cerebrospinal fluid (CSF) analysis and are being increasingly used in clinical practice to support an AD diagnosis. Recently, […]
Source link : https://www.newshealth.biz/health-news/acip-recommends-pcv-for-adults-aged-50-years-or-older/ The US Centers for Disease Control and Prevention’s (CDC’s) Advisory Committee on Immunization Practices (ACIP) now recommends a pneumococcal conjugate vaccine (PCV) for all PCV-naive adults aged 50 years or older. The new recommendation, which passed with an ACIP member vote of 14 for and one against, expands the current age-based […]
Source link : https://www.newshealth.biz/health-news/a-dermatologists-tips-for-supporting-lgbtq-youth/ HUNTINGTON BEACH, Calif. — Dermatologists who believe they have little to offer LGBTQ children and adolescents beyond routine care, Markus Boos, MD, PhD, urges them to consider the potential impact they can have on these patients. Markus Boos, MD, PhD “Sometimes in dermatology we might say, ‘This gender care stuff, that’s […]
Source link : https://www.newshealth.biz/health-news/lucy-letby-loses-bid-to-appeal-against-conviction/ Convicted killer Lucy Letby’s bid to appeal against her latest conviction for the attempted murder of a baby girl has been dismissed by the Court of Appeal. Letby’s lawyers asked senior judges for approval to appeal against her most recent conviction, which followed a retrial in July for a charge of […]
Source link : https://www.newshealth.biz/health-news/uk-regulator-tells-doctors-to-watch-for-obesity-injection-misuse/ The UK’s drug safety regulator is asking doctors to be alert for patients who may be misusing obesity injections, such as Wegovy. It follows reports of some people who are not obese becoming sick, after using the jabs for weight loss. The Medicines and Healthcare products Regulatory Agency (MHRA) stresses that […]
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Mepivacaine Reduces IUD Placement Pain
Source link : https://www.newshealth.biz/health-news/mepivacaine-reduces-iud-placement-pain/ TOPLINE: Mepivacaine instillation significantly reduced pain during intrauterine device (IUD) placement in nulliparous women. More than 90% of women in the intervention group reported tolerable pain compared with 80% of those in the placebo group. METHODOLOGY: A multicenter, double-blind, randomized, placebo-controlled trial was conducted in 12 centers in Sweden, which involved […]
Source link : https://www.newshealth.biz/health-news/video-laryngoscopy-improves-success-rate-of-emergency-tracheal-intubation/ TOPLINE: In critically ill patients, video laryngoscopy offers superior glottic visualization, reduces the incidence of esophageal intubation, and improves the first-attempt success rate of emergency tracheal intubation in hospital but not in prehospital settings. METHODOLOGY: Researchers conducted a systematic review and meta-analysis of 26 randomized controlled trials with 5952 critically ill […]
Source link : https://www.newshealth.biz/health-news/fm-led-obstetric-units-achieve-lower-c-section-rates/ Labor and delivery centers run by family medicine (FM) healthcare providers have a lower cesarean delivery rate and better safety culture than centers led by obstetricians (OBs), based on observational data from Iowa hospitals. These findings show how FM providers backed up by general surgeons can deliver a high standard of […]
Source link : https://www.newshealth.biz/health-news/small-increase-in-breast-cancer-with-levonorgestrel-iud/ TOPLINE: The use of a levonorgestrel-releasing intrauterine system (LNG-IUS) is associated with an increased risk for breast cancer. An analysis by Danish researchers found 14 extra cases of breast cancer per 10,000 women using this type of an intrauterine device (IUD) vs women not using hormonal contraceptives. METHODOLOGY: The investigators used […]